The Melnick lab is based in New York City at the Sandra and Edward Meyer Cancer Center of the Weill Cornell Medical College and NewYork-Presbyterian Hospital.
The Melnick lab's mission is to investigate the molecular underpinnings of cancer, and devise new treatments that combine lab and clinical innovations to directly benefit patients.
Our aim is to understand the mechanisms through which transcriptional and epigenetic regulation occur during normal differentiation and how these processes become disrupted in human leukemias and lymphomas and to use this information to develop specific and potent therapeutic strategies.
- The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs.
- Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML.
- Targeted detection and quantitation of histone modifications from 1,000 cells.
- Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage.
"Basic research is what I'm doing when I don't know what I'm doing." - Werner Von Braun