Publications

2021

Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence., C. Duy; M. Li; M. Teater; C. Meydan; F.E. Garrett-Bakelman; T.C. Lee; C.R. Chin; C. Durmaz; K.C. Kawabata; E. Dhimolea; C.S. Mitsiades; H. Doehner; R.J. D'Andrea; M.W. Becker; E.M. Paietta; C.E. Mason; M. Carroll; A.M. Melnick, Cancer Discov, 2021 Jun, 11, 6, p.1542-1561, (2021) PubMed

Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation., M.A. Rivas; C. Meydan; C.R. Chin; M.F. Challman; D. Kim; B. Bhinder; A. Kloetgen; A.D. Viny; M.R. Teater; D.R. McNally; A.S. Doane; W. Béguelin; M.Teresa Cal Fernández; H. Shen; X. Wang; R.L. Levine; Z. Chen; A. Tsirigos; O. Elemento; C.E. Mason; A.M. Melnick, Nat Immunol, 2021 Feb, 22, 2, p.240-253, (2021) PubMed

H1 histones control the epigenetic landscape by local chromatin compaction., M.A. Willcockson; S.E. Healton; C.N. Weiss; B.A. Bartholdy; Y. Botbol; L.N. Mishra; D.S. Sidhwani; T.J. Wilson; H.B. Pinto; M.I. Maron; K.A. Skalina; L.Norwood Toro; J. Zhao; C.H. Lee; H. Hou; N. Yusufova; C. Meydan; A. Osunsade; Y. David; E. Cesarman; A.M. Melnick; S. Sidoli; B.A. Garcia; W. Edelmann; F. Macian; A.I. Skoultchi, Nature, 2021 Jan, 589, 7841, p.293-298, (2021) PubMed

An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities., R. Flümann; T. Rehkämper; P. Nieper; P. Pfeiffer; A. Holzem; S. Klein; S. Bhatia; M. Kochanek; I. Kisis; B.W. Pelzer; H. Ahlert; J. Hauer; Ada Palma Guerreiro; J.A. Ryan; M. Reimann; A. Riabinska; J. Wiederstein; M. Krüger; M. Deckert; J. Altmüller; A.R. Klatt; L.P. Frenzel; L. Pasqualucci; W. Béguelin; A.M. Melnick; S. Sander; M. Montesinos-Rongen; A. Brunn; P. Lohneis; R. Büttner; H. Kashkar; A. Borkhardt; A. Letai; T. Persigehl; M. Peifer; C.A. Schmitt; H.Christian Reinhardt; G. Knittel, Blood Cancer Discov, 2021 Jan, 2, 1, p.70-91, (2021) PubMed

Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture., N. Yusufova; A. Kloetgen; M. Teater; A. Osunsade; J.M. Camarillo; C.R. Chin; A.S. Doane; B.J. Venters; S. Portillo-Ledesma; J. Conway; J.M. Phillip; O. Elemento; D.W. Scott; W. Béguelin; J.D. Licht; N.L. Kelleher; L.M. Staudt; A.I. Skoultchi; M.C. Keogh; E. Apostolou; C.E. Mason; M. Imielinski; T. Schlick; Y. David; A. Tsirigos; D. Allis; A.A. Soshnev; E. Cesarman; A.M. Melnick, Nature, 2021 Jan, 589, 7841, p.299-305, (2021) PubMed

2020

The therapeutic landscape for cells engineered with chimeric antigen receptors., M. MacKay; E. Afshinnekoo; J. Rub; C. Hassan; M. Khunte; N. Baskaran; B. Owens; L. Liu; G.J. Roboz; M.L. Guzman; A.M. Melnick; S. Wu; C.E. Mason, Nat Biotechnol, 2020 Feb, 38, 2, p.233-244, (2020) PubMed

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions., D.J. Butler; C. Mozsary; C. Meydan; D. Danko; J. Foox; J. Rosiene; A. Shaiber; E. Afshinnekoo; M. MacKay; F.J. Sedlazeck; N.A. Ivanov; M. Sierra; D. Pohle; M. Zietz; U. Gisladottir; V. Ramlall; C.D. Westover; K. Ryon; B. Young; C. Bhattacharya; P. Ruggiero; B.W. Langhorst; N. Tanner; J. Gawrys; D. Meleshko; D. Xu; P.A.D. Steel; A.J. Shemesh; J. Xiang; J. Thierry-Mieg; D. Thierry-Mieg; R.E. Schwartz; A. Iftner; D. Bezdan; J. Sipley; L. Cong; A. Craney; P. Velu; A.M. Melnick; I. Hajirasouliha; S.M. Horner; T. Iftner; M. Salvatore; M. Loda; L.F. Westblade; M. Cushing; S. Levy; S. Wu; N. Tatonetti; M. Imielinski; H. Rennert; C.E. Mason, bioRxiv, 2020 May 01, , , p., (2020) PubMed

Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage., C.S. Chu; J.C. Hellmuth; R. Singh; H.Y. Ying; L. Skrabanek; M.R. Teater; A.S. Doane; O. Elemento; A.M. Melnick; R.G. Roeder, Mol Cell, 2020 Dec 03, 80, 5, p.845-861.e10, (2020) PubMed

The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs., L. Venturutti; A.M. Melnick, Blood, 2020 Nov 12, 136, 20, p.2263-2274, (2020) PubMed

Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., W. Béguelin; M. Teater; C. Meydan; K.B. Hoehn; J.M. Phillip; A.A. Soshnev; L. Venturutti; M.A. Rivas; M.T. Calvo-Fernández; J. Gutierrez; J.M. Camarillo; K. Takata; K. Tarte; N.L. Kelleher; C. Steidl; C.E. Mason; O. Elemento; D. Allis; S.H. Kleinstein; A.M. Melnick, Cancer Cell, 2020 May 11, 37, 5, p.655-673.e11, (2020) PubMed