Publications

2020

Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., W. Béguelin; M. Teater; C. Meydan; K.B. Hoehn; J.M. Phillip; A.A. Soshnev; L. Venturutti; M.A. Rivas; M.T. Calvo-Fernández; J. Gutierrez; J.M. Camarillo; K. Takata; K. Tarte; N.L. Kelleher; C. Steidl; C.E. Mason; O. Elemento; D. Allis; S.H. Kleinstein; A.M. Melnick, Cancer Cell, 2020 May 11, 37, 5, p.655-673.e11, (2020) PubMed

Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage., C.S. Chu; J.C. Hellmuth; R. Singh; H.Y. Ying; L. Skrabanek; M.R. Teater; A.S. Doane; O. Elemento; A.M. Melnick; R.G. Roeder, Mol Cell, 2020 Dec 03, 80, 5, p.845-861.e10, (2020) PubMed

The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs., L. Venturutti; A.M. Melnick, Blood, 2020 Nov 12, 136, 20, p.2263-2274, (2020) PubMed

The therapeutic landscape for cells engineered with chimeric antigen receptors., M. MacKay; E. Afshinnekoo; J. Rub; C. Hassan; M. Khunte; N. Baskaran; B. Owens; L. Liu; G.J. Roboz; M.L. Guzman; A.M. Melnick; S. Wu; C.E. Mason, Nat Biotechnol, 2020 Feb, 38, 2, p.233-244, (2020) PubMed

TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate., L. Venturutti; M. Teater; A. Zhai; A. Chadburn; L. Babiker; D. Kim; W. Béguelin; T.C. Lee; Y. Kim; C.R. Chin; W.T. Yewdell; B. Raught; J.M. Phillip; Y. Jiang; L.M. Staudt; M.R. Green; J. Chaudhuri; O. Elemento; P. Farinha; A.P. Weng; M.D. Nissen; C. Steidl; R.D. Morin; D.W. Scott; G.G. Prive; A.M. Melnick, Cell, 2020 Jul 23, 182, 2, p.297-316.e27, (2020) PubMed

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., M.S. Fabre; N.M. Stanton; T.L. Slatter; S. Lee; D. Senanayake; R.M.A. Gordon; L. Castro; M.R. Rowe; A. Taha; J.A. Royds; N. Hung; A.M. Melnick; M.J. McConnell, PLoS One, 2020, 15, 4, p.e0231470, (2020) PubMed

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers., D. Bezdan; K. Grigorev; C. Meydan; F.A.Pelissie Vatter; M. Cioffi; V. Rao; M. MacKay; K. Nakahira; P. Burnham; E. Afshinnekoo; C. Westover; D. Butler; C. Mozsary; T. Donahoe; J. Foox; T. Mishra; S. Lucotti; B.K. Rana; A.M. Melnick; H. Zhang; I. Matei; D. Kelsen; K. Yu; D.C. Lyden; L. Taylor; S.M. Bailey; M.P. Snyder; F.E. Garrett-Bakelman; S. Ossowski; I. De Vlaminck; C.E. Mason, iScience, 2020 Dec 18, 23, 12, p.101844, (2020) PubMed

Targeted detection and quantitation of histone modifications from 1,000 cells., N.A. Abshiru; J.W. Sikora; J.M. Camarillo; J.A. Morris; P.D. Compton; T. Lee; Y. Neelamraju; S. Haddox; C. Sheridan; M. Carroll; L.D. Cripe; M.S. Tallman; E.M. Paietta; A.M. Melnick; P.M. Thomas; F.E. Garrett-Bakelman; N.L. Kelleher, PLoS One, 2020, 15, 10, p.e0240829, (2020) PubMed

2019

BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress., T.M. Fernando; R. Marullo; B.Pera Gresely; J.M. Phillip; S.Ning Yang; G. Lundell-Smith; I. Torregroza; H. Ahn; T. Evans; B. Gyorffy; G.G. Prive; M. Hirano; A.M. Melnick; L. Cerchietti, Cancer Discov, 2019 May, 9, 5, p.662-679, (2019) PubMed

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML., C. Duy; M. Teater; F.E. Garrett-Bakelman; T.C. Lee; C. Meydan; J.L. Glass; M. Li; J.C. Hellmuth; H.P. Mohammad; K.N. Smitheman; A.H. Shih; O. Abdel-Wahab; M.S. Tallman; M.L. Guzman; D. Muench; L. Grimes; G.J. Roboz; R.G. Kruger; C.L. Creasy; E.M. Paietta; R.L. Levine; M. Carroll; A.M. Melnick, Cancer Discov, 2019 Jul, 9, 7, p.872-889, (2019) PubMed