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Melnick Lab

Publications

2020

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers., D. Bezdan; K. Grigorev; C. Meydan; F.A.Pelissie Vatter; M. Cioffi; V. Rao; M. MacKay; K. Nakahira; P. Burnham; E. Afshinnekoo; C. Westover; D. Butler; C. Mozsary; T. Donahoe; J. Foox; T. Mishra; S. Lucotti; B.K. Rana; A.M. Melnick; H. Zhang; I. Matei; D. Kelsen; K. Yu; D.C. Lyden; L. Taylor; S.M. Bailey; M.P. Snyder; F.E. Garrett-Bakelman; S. Ossowski; I. De Vlaminck; C.E. Mason, iScience, 2020 Dec 18, 23, 12, p.101844, (2020) PubMed
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML., S. Li; X. Chen; J. Wang; C. Meydan; J.L. Glass; A.H. Shih; R. Delwel; R.L. Levine; C.E. Mason; A.M. Melnick, Cancer Discov, 2020 12, 10, 12, p.1934-1949, (2020) PubMed
Clonal Hematopoiesis Before, During, and After Human Spaceflight., N. Mencia-Trinchant; M.J. MacKay; C. Chin; E. Afshinnekoo; J. Foox; C. Meydan; D. Butler; C. Mozsary; N.A. Vernice; C. Darby; M.C. Schatz; S.M. Bailey; A.M. Melnick; M.L. Guzman; K. Bolton; L.Z. Braunstein; F. Garrett-Bakelman; R.L. Levine; D.C. Hassane; C.E. Mason, Cell Rep, 2020 12 08, 33, 10, p.108458, (2020) PubMed
The therapeutic landscape for cells engineered with chimeric antigen receptors., M. MacKay; E. Afshinnekoo; J. Rub; C. Hassan; M. Khunte; N. Baskaran; B. Owens; L. Liu; G.J. Roboz; M.L. Guzman; A.M. Melnick; S. Wu; C.E. Mason, Nat Biotechnol, 2020 02, 38, 2, p.233-244, (2020) PubMed
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate., L. Venturutti; M. Teater; A. Zhai; A. Chadburn; L. Babiker; D. Kim; W. Béguelin; T.C. Lee; Y. Kim; C.R. Chin; W.T. Yewdell; B. Raught; J.M. Phillip; Y. Jiang; L.M. Staudt; M.R. Green; J. Chaudhuri; O. Elemento; P. Farinha; A.P. Weng; M.D. Nissen; C. Steidl; R.D. Morin; D.W. Scott; G.G. Prive; A.M. Melnick, Cell, 2020 07 23, 182, 2, p.297-316.e27, (2020) PubMed
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., M.S. Fabre; N.M. Stanton; T.L. Slatter; S. Lee; D. Senanayake; R.M.A. Gordon; L. Castro; M.R. Rowe; A. Taha; J.A. Royds; N. Hung; A.M. Melnick; M.J. McConnell, PLoS One, 2020, 15, 4, p.e0231470, (2020) PubMed
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage., C.S. Chu; J.C. Hellmuth; R. Singh; H.Y. Ying; L. Skrabanek; M.R. Teater; A.S. Doane; O. Elemento; A.M. Melnick; R.G. Roeder, Mol Cell, 2020 12 03, 80, 5, p.845-861.e10, (2020) PubMed
The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs., L. Venturutti; A.M. Melnick, Blood, 2020 11 12, 136, 20, p.2263-2274, (2020) PubMed

2019

Peptide-based covalent inhibitors of MALT1 paracaspase., J.M. Hatcher; G. Du; L. Fontan; I. Us; Q. Qiao; S. Chennamadhavuni; J. Shao; H. Wu; A. Melnick; N.S. Gray; D.A. Scott, Bioorg Med Chem Lett, 2019 06 01, 29, 11, p.1336-1339, (2019) PubMed
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., X. Lu; C.S. Chu; T. Fang; V. Rayon-Estrada; F. Fang; A. Patke; Y. Qian; S.H. Clarke; A.M. Melnick; Y. Zhang; N. Papavasiliou; R.G. Roeder, Cell Rep, 2019 07 09, 28, 2, p.472-485.e5, (2019) PubMed