Publications

2015

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program., S.M. Park; M. Gönen; L. Vu; G. Minuesa; P. Tivnan; T.S. Barlowe; J. Taggart; Y. Lu; R.P. Deering; N. Hacohen; M.E. Figueroa; E. Paietta; H.F. Fernandez; M.S. Tallman; A. Melnick; R. Levine; C. Leslie; C.J. Lengner; M.G. Kharas, J Clin Invest, 2015 Mar 02, 125, 3, p.1286-98, (2015) PubMed

Mechanisms of action of BCL6 during germinal center B cell development., C.X. Huang; A. Melnick, Sci China Life Sci, 2015 Dec, 58, 12, p.1226-32, (2015) PubMed

A roadmap for discovery and translation in lymphoma., D.M. Weinstock; R. Dalla-Favera; R.D. Gascoyne; J.P. Leonard; R. Levy; I.S. Lossos; A.M. Melnick; G.S. Nowakowski; O.W. Press; K.J. Savage; M.A. Shipp; L.M. Staudt, Blood, 2015 Mar 26, 125, 13, p.2175-7, (2015) PubMed

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., R.L. Goldstein; S.Ning Yang; T. Taldone; B. Chang; J. Gerecitano; K. Elenitoba-Johnson; R. Shaknovich; W. Tam; J.P. Leonard; G. Chiosis; L. Cerchietti; A. Melnick, J Clin Invest, 2015 Nov 03, 125, 12, p.4559-71, (2015) PubMed

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Y.F. Tian; H. Ahn; R.S. Schneider; S.Ning Yang; L. Roman-Gonzalez; A.M. Melnick; L. Cerchietti; A. Singh, Biomaterials, 2015 Dec, 73, , p.110-9, (2015) PubMed

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., K.M. Noh; H. Wang; H.R. Kim; W. Wenderski; F. Fang; C.H. Li; S. Dewell; S.H. Hughes; A.M. Melnick; D.J. Patel; H. Li; D. Allis, Mol Cell, 2015 Jul 02, 59, 1, p.89-103, (2015) PubMed

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., A.H. Shih; Y. Jiang; C. Meydan; K. Shank; S. Pandey; L. Barreyro; I. Antony-Debre; A. Viale; N. Socci; Y. Sun; A. Robertson; M. Cavatore; E. de Stanchina; T. Hricik; F. Rapaport; B. Woods; C. Wei; M. Hatlen; M. Baljevic; S.D. Nimer; M. Tallman; E. Paietta; L. Cimmino; I. Aifantis; U. Steidl; C. Mason; A. Melnick; R.L. Levine, Cancer Cell, 2015 Apr 13, 27, 4, p.502-15, (2015) PubMed

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., M. Buchner; E. Park; H. Geng; L. Klemm; J. Flach; E. Passegué; H. Schjerven; A. Melnick; E. Paietta; D. Kopanja; P. Raychaudhuri; M. Müschen, Nat Commun, 2015 Mar 10, 6, , p.6471, (2015) PubMed

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers., X. Agirre; G. Castellano; M. Pascual; S. Heath; M. Kulis; V. Segura; A. Bergmann; A. Esteve; A. Merkel; E. Raineri; L. Agueda; J. Blanc; D. Richardson; L. Clarke; A. Datta; N. Russiñol; A.C. Queirós; R. Beekman; J.R. Rodríguez-Madoz; E. San José-Enériz; F. Fang; N.C. Gutiérrez; J.M. García-Verdugo; M.I. Robson; E.C. Schirmer; E. Guruceaga; J.H.A. Martens; M. Gut; M.J. Calasanz; P. Flicek; R. Siebert; E. Campo; J.F. San Miguel; A. Melnick; H.G. Stunnenberg; I.G. Gut; F. Prosper; J.I. Martín-Subero, Genome Res, 2015 Apr, 25, 4, p.478-87, (2015) PubMed

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma., Y. Jiang; K. Nie; D. Redmond; A.M. Melnick; W. Tam; O. Elemento, J Vis Exp, 2015 Dec 28, , 106, p.e53215, (2015) PubMed