Melnick Lab

Publications

2019

MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., X. Lu; C.S. Chu; T. Fang; V. Rayon-Estrada; F. Fang; A. Patke; Y. Qian; S.H. Clarke; A.M. Melnick; Y. Zhang; N. Papavasiliou; R.G. Roeder, Cell Rep, 2019 07 09, 28, 2, p.472-485.e5, (2019) PubMed

Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells., A. Purwada; S.B. Shah; W. Béguelin; A. August; A.M. Melnick; A. Singh, Biomaterials, 2019 04, 198, , p.27-36, (2019) PubMed

The Impact of Heterogeneity on Single-Cell Sequencing., S.L. Goldman; M. MacKay; E. Afshinnekoo; A.M. Melnick; S. Wu; C.E. Mason, Front Genet, 2019, 10, , p.8, (2019) PubMed

An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming?, M. Li; A.M. Melnick, Cancer Discov, 2019 Sep, 9, 9, p.1158-1160, (2019) PubMed

Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis., K. Hatzi; H. Geng; A.S. Doane; C. Meydan; R. LaRiviere; M. Cardenas; C. Duy; H. Shen; M.Nieves Cal Vidal; T. Baslan; H.P. Mohammad; R.G. Kruger; R. Shaknovich; A.M. Haberman; G. Inghirami; S.W. Lowe; A.M. Melnick, Nat Immunol, 2019 01, 20, 1, p.86-96, (2019) PubMed

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL., A. Pastore; F. Gaiti; S.X. Lu; R.M. Brand; S. Kulm; R. Chaligne; H. Gu; K.Y. Huang; E.K. Stamenova; W. Béguelin; Y. Jiang; R.C. Schulman; K.T. Kim; A. Alonso; J.N. Allan; R.R. Furman; A. Gnirke; C.J. Wu; A.M. Melnick; A. Meissner; B.E. Bernstein; O. Abdel-Wahab; D.A. Landau, Nat Commun, 2019 04 23, 10, 1, p.1874, (2019) PubMed

Germinal center-derived lymphomas: The darkest side of humoral immunity., C. Mlynarczyk; L. Fontan; A. Melnick, Immunol Rev, 2019 03, 288, 1, p.214-239, (2019) PubMed

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., F.E. Garrett-Bakelman; M. Darshi; S.J. Green; R.C. Gur; L. Lin; B.R. Macias; M.J. McKenna; C. Meydan; T. Mishra; J. Nasrini; B.D. Piening; L.F. Rizzardi; K. Sharma; J.H. Siamwala; L. Taylor; M.Hotz Vitaterna; M. Afkarian; E. Afshinnekoo; S. Ahadi; A. Ambati; M. Arya; D. Bezdan; C.M. Callahan; S. Chen; A.M.K. Choi; G.E. Chlipala; K. Contrepois; M. Covington; B.E. Crucian; I. De Vivo; D.F. Dinges; D.J. Ebert; J.I. Feinberg; J.A. Gandara; K.A. George; J. Goutsias; G.S. Grills; A.R. Hargens; M. Heer; R.P. Hillary; A.N. Hoofnagle; V.Y.H. Hook; G. Jenkinson; P. Jiang; A. Keshavarzian; S.S. Laurie; B. Lee-McMullen; S.B. Lumpkins; M. MacKay; M.G. Maienschein-Cline; A.M. Melnick; T.M. Moore; K. Nakahira; H.H. Patel; R. Pietrzyk; V. Rao; R. Saito; D.N. Salins; J.M. Schilling; D.D. Sears; C.K. Sheridan; M.B. Stenger; R. Tryggvadottir; A.E. Urban; T. Vaisar; B. Van Espen; J. Zhang; M.G. Ziegler; S.R. Zwart; J.B. Charles; C.E. Kundrot; G.B.I. Scott; S.M. Bailey; M. Basner; A.P. Feinberg; S.M.C. Lee; C.E. Mason; E. Mignot; B.K. Rana; S.M. Smith; M.P. Snyder; F.W. Turek, Science, 2019 04 12, 364, 6436, p., (2019) PubMed

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., M. Li; Y.L. Chiang; C.A. Lyssiotis; M.R. Teater; J.Young Hong; H. Shen; L. Wang; J. Hu; H. Jing; Z. Chen; N. Jain; C. Duy; S.J. Mistry; L. Cerchietti; J.R. Cross; L.C. Cantley; M.R. Green; H. Lin; A.M. Melnick, Cancer Cell, 2019 06 10, 35, 6, p.916-931.e9, (2019) PubMed

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease., K. Paz; R. Flynn; J. Du; J. Qi; L. Luznik; I. Maillard; K.P. MacDonald; G.R. Hill; J.S. Serody; W.J. Murphy; P.T. Sage; A.H. Sharpe; D. Miklos; C.S. Cutler; J. Koreth; J.H. Antin; R.J. Soiffer; J. Ritz; J.E. Bradner; A.M. Melnick; B.R. Blazar, Blood, 2019 01 03, 133, 1, p.94-99, (2019) PubMed