Publications

2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., F.E. Garrett-Bakelman; M. Darshi; S.J. Green; R.C. Gur; L. Lin; B.R. Macias; M.J. McKenna; C. Meydan; T. Mishra; J. Nasrini; B.D. Piening; L.F. Rizzardi; K. Sharma; J.H. Siamwala; L. Taylor; M.Hotz Vitaterna; M. Afkarian; E. Afshinnekoo; S. Ahadi; A. Ambati; M. Arya; D. Bezdan; C.M. Callahan; S. Chen; A.M.K. Choi; G.E. Chlipala; K. Contrepois; M. Covington; B.E. Crucian; I. De Vivo; D.F. Dinges; D.J. Ebert; J.I. Feinberg; J.A. Gandara; K.A. George; J. Goutsias; G.S. Grills; A.R. Hargens; M. Heer; R.P. Hillary; A.N. Hoofnagle; V.Y.H. Hook; G. Jenkinson; P. Jiang; A. Keshavarzian; S.S. Laurie; B. Lee-McMullen; S.B. Lumpkins; M. MacKay; M.G. Maienschein-Cline; A.M. Melnick; T.M. Moore; K. Nakahira; H.H. Patel; R. Pietrzyk; V. Rao; R. Saito; D.N. Salins; J.M. Schilling; D.D. Sears; C.K. Sheridan; M.B. Stenger; R. Tryggvadottir; A.E. Urban; T. Vaisar; B. Van Espen; J. Zhang; M.G. Ziegler; S.R. Zwart; J.B. Charles; C.E. Kundrot; G.B.I. Scott; S.M. Bailey; M. Basner; A.P. Feinberg; S.M.C. Lee; C.E. Mason; E. Mignot; B.K. Rana; S.M. Smith; M.P. Snyder; F.W. Turek, Science, 2019 Apr 12, 364, 6436, p., (2019) PubMed

Germinal center-derived lymphomas: The darkest side of humoral immunity., C. Mlynarczyk; L. Fontan; A. Melnick, Immunol Rev, 2019 Mar, 288, 1, p.214-239, (2019) PubMed

MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., X. Lu; C.S. Chu; T. Fang; V. Rayon-Estrada; F. Fang; A. Patke; Y. Qian; S.H. Clarke; A.M. Melnick; Y. Zhang; N. Papavasiliou; R.G. Roeder, Cell Rep, 2019 Jul 09, 28, 2, p.472-485.e5, (2019) PubMed

Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization., A.P. Gomes; D. Ilter; V. Low; A. Rosenzweig; Z.J. Shen; T. Schild; M.A. Rivas; E.E. Er; D.R. McNally; A.P. Mutvei; J. Han; Y.H. Ou; P. Cavaliere; E. Mullarky; M. Nagiec; S. Shin; S.O. Yoon; N. Dephoure; J. Massagué; A.M. Melnick; L.C. Cantley; J.K. Tyler; J. Blenis, Cancer Cell, 2019 Oct 14, 36, 4, p.402-417.e13, (2019) PubMed

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition., D. Ennishi; K. Takata; W. Béguelin; G. Duns; A. Mottok; P. Farinha; A. Bashashati; S. Saberi; M. Boyle; B. Meissner; S. Ben-Neriah; B.W. Woolcock; A. Telenius; D. Lai; M. Teater; R. Kridel; K.J. Savage; L.H. Sehn; R.D. Morin; M.A. Marra; S.P. Shah; J.M. Connors; R.D. Gascoyne; D.W. Scott; A.M. Melnick; C. Steidl, Cancer Discov, 2019 Apr, 9, 4, p.546-563, (2019) PubMed

Role of chromosomal architecture in germinal center B cells and lymphomagenesis., M.A. Rivas; A.M. Melnick, Curr Opin Hematol, 2019 Jul, 26, 4, p.294-302, (2019) PubMed

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas., M. Pascual; M. Mena-Varas; E.Francisco Robles; M.J. Garcia-Barchino; C. Panizo; S. Hervas-Stubbs; D. Alignani; A. Sagardoy; J.Ignacio Martinez-Ferrandis; K.L. Bunting; S. Meier; X. Sagaert; D. Bagnara; E. Guruceaga; O. Blanco; J. Celay; A. Martínez-Baztan; N. Casares; J.José Lasarte; T. MacCarthy; A. Melnick; J.Angel Martínez-Climent; S. Roa, Blood, 2019 May 30, 133, 22, p.2401-2412, (2019) PubMed

Emerging epigenetic-modulating therapies in lymphoma., D. Sermer; L. Pasqualucci; H.G. Wendel; A. Melnick; A. Younes, Nat Rev Clin Oncol, 2019 Aug, 16, 8, p.494-507, (2019) PubMed

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., M. Li; Y.L. Chiang; C.A. Lyssiotis; M.R. Teater; J.Young Hong; H. Shen; L. Wang; J. Hu; H. Jing; Z. Chen; N. Jain; C. Duy; S.J. Mistry; L. Cerchietti; J.R. Cross; L.C. Cantley; M.R. Green; H. Lin; A.M. Melnick, Cancer Cell, 2019 Jun 10, 35, 6, p.916-931.e9, (2019) PubMed

Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells., A. Purwada; S.B. Shah; W. Béguelin; A. August; A.M. Melnick; A. Singh, Biomaterials, 2019 Apr, 198, , p.27-36, (2019) PubMed