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Publications

2018

Untangling the Role of Polycomb Complexes in Chemotherapy Resistance., C. Duy; A. Melnick, Cancer Discov, 2018 11, 8, 11, p.1348-1351, (2018) PubMed

2017

The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target., M.G. Cardenas; E. Oswald; W. Yu; F. Xue; A.D. MacKerell; A.M. Melnick, Clin Cancer Res, 2017 Feb 15, 23, 4, p.885-893, (2017) PubMed

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., R.D. Gascoyne; B. Nadel; L. Pasqualucci; J. Fitzgibbon; J.E. Payton; A. Melnick; O. Weigert; K. Tarte; J.G. Gribben; J.W. Friedberg; J.F. Seymour; F. Cavalli; E. Zucca, Hematol Oncol, 2017 Dec, 35, 4, p.397-407, (2017) PubMed

The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells., L.P. Vu; B.F. Pickering; Y. Cheng; S. Zaccara; D. Nguyen; G. Minuesa; T. Chou; A. Chow; Y. Saletore; M. MacKay; J. Schulman; C. Famulare; M. Patel; V.M. Klimek; F.E. Garrett-Bakelman; A. Melnick; M. Carroll; C.E. Mason; S.R. Jaffrey; M.G. Kharas, Nat Med, 2017 Nov, 23, 11, p.1369-1376, (2017) PubMed

Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury., Y. Li; X. Huang; S. Huang; H. He; T. Lei; F. Saaoud; X.Q. Yu; A. Melnick; A. Kumar; C.J. Papasian; D. Fan; M. Fu, Signal Transduct Target Ther, 2017, 2, , p.17066, (2017) PubMed

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., J.L. Glass; D. Hassane; B.J. Wouters; H. Kunimoto; R. Avellino; F.E. Garrett-Bakelman; O.A. Guryanova; R. Bowman; S. Redlich; A.M. Intlekofer; C. Meydan; T. Qin; M. Fall; A. Alonso; M.L. Guzman; P.J.M. Valk; C.B. Thompson; R. Levine; O. Elemento; R. Delwel; A. Melnick; M.E. Figueroa, Cancer Discov, 2017 08, 7, 8, p.868-883, (2017) PubMed

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model., W. Du; R. Goldstein; Y. Jiang; O. Aly; L. Cerchietti; A. Melnick; O. Elemento, Cancer Res, 2017 04 15, 77, 8, p.1818-1830, (2017) PubMed

DNA Methylation-Based Biomarkers., L. Cerchietti; A. Melnick, J Clin Oncol, 2017 03, 35, 7, p.793-795, (2017) PubMed

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells., E. Valls; C. Lobry; H. Geng; L. Wang; M. Cardenas; M. Rivas; L. Cerchietti; P. Oh; S.Ning Yang; E. Oswald; C.W. Graham; Y. Jiang; K. Hatzi; X. Agirre; E. Perkey; Z. Li; W. Tam; K. Bhatt; J.P. Leonard; P.A. Zweidler-McKay; I. Maillard; O. Elemento; W. Ci; I. Aifantis; A. Melnick, Cancer Discov, 2017 05, 7, 5, p.506-521, (2017) PubMed

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., W. Béguelin; M.A. Rivas; M.T.Calvo Fernández; M. Teater; A. Purwada; D. Redmond; H. Shen; M.F. Challman; O. Elemento; A. Singh; A.M. Melnick, Nat Commun, 2017 10 12, 8, 1, p.877, (2017) PubMed