Publications

2016

The epichaperome is an integrated chaperome network that facilitates tumour survival., A. Rodina; T. Wang; P. Yan; E.DaGama Gomes; M.P.S. Dunphy; N. Pillarsetty; J. Koren; J.F. Gerecitano; T. Taldone; H. Zong; E. Caldas-Lopes; M. Alpaugh; A. Corben; M. Riolo; B. Beattie; C. Pressl; R.I. Peter; C. Xu; R. Trondl; H.J. Patel; F. Shimizu; A. Bolaender; C. Yang; P. Panchal; M.F. Farooq; S. Kishinevsky; S. Modi; O. Lin; F. Chu; S. Patil; H. Erdjument-Bromage; P. Zanzonico; C. Hudis; L. Studer; G.J. Roboz; E. Cesarman; L. Cerchietti; R. Levine; A. Melnick; S.M. Larson; J.S. Lewis; M.L. Guzman; G. Chiosis, Nature, 2016 Oct 20, 538, 7625, p.397-401, (2016) PubMed

Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., F.E. Garrett-Bakelman; A.M. Melnick, Epigenomics, 2016 07, 8, 7, p.945-57, (2016) PubMed

General Biomarker Recommendations for Lymphoma., L. Rimsza; Y. Fedoriw; L.M. Staudt; A. Melnick; R. Gascoyne; M. Crump; L. Baizer; K. Fu; E. Hsi; J.W.C. Chan; L. McShane; J.P. Leonard; B.S. Kahl; R.F. Little; J.W. Friedberg; L. Kostakoglu, J Natl Cancer Inst, 2016 12, 108, 12, p., (2016) PubMed

A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia., M.R. Luskin; P.A. Gimotty; C. Smith; A.W. Loren; M.E. Figueroa; J. Harrison; Z. Sun; M.S. Tallman; E.M. Paietta; M.R. Litzow; A.M. Melnick; R.L. Levine; H.F. Fernandez; S.M. Luger; M. Carroll; S.R. Master; G.B.W. Wertheim, JCI Insight, 2016 Jun 16, 1, 9, p., (2016) PubMed

Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"., L.M. LaFave; W. Béguelin; R. Koche; M. Teater; B. Spitzer; A. Chramiec; E. Papalexi; M.D. Keller; T. Hricik; K. Konstantinoff; J.B. Micol; B. Durham; S.K. Knutson; J.E. Campbell; G. Blum; X. Shi; E.H. Doud; A.V. Krivtsov; Y.Rock Chung; I. Khodos; E. de Stanchina; O. Ouerfelli; P.S. Adusumilli; P.M. Thomas; N.L. Kelleher; M. Luo; H. Keilhack; O. Abdel-Wahab; A. Melnick; S.A. Armstrong; R.L. Levine, Nat Med, 2016 06 07, 22, 6, p.578-9, (2016) PubMed

DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia., S.E. Meyer; T. Qin; D.E. Muench; K. Masuda; M. Venkatasubramanian; E. Orr; L. Suarez; S.D. Gore; R. Delwel; E. Paietta; M.S. Tallman; H. Fernandez; A. Melnick; M.M. Le Beau; S. Kogan; N. Salomonis; M.E. Figueroa; L. Grimes, Cancer Discov, 2016 05, 6, 5, p.501-15, (2016) PubMed

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas., B. Culjkovic-Kraljacic; T.M. Fernando; R. Marullo; N. Calvo-Vidal; A. Verma; S.N. Yang; F. Tabbò; M. Gaudiano; H. Zahreddine; R.L. Goldstein; J. Patel; T. Taldone; G. Chiosis; M. Ladetto; P. Ghione; R. Machiorlatti; O. Elemento; G. Inghirami; A. Melnick; K.L.B. Borden; L. Cerchietti, Blood, 2016 Feb 18, 127, 7, p.858-68, (2016) PubMed

Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma., N.S. Saba; D. Liu; S.E.M. Herman; C. Underbayev; X. Tian; D. Behrend; M.A. Weniger; M. Skarzynski; J. Gyamfi; L. Fontan; A. Melnick; C. Grant; M. Roschewski; A. Navarro; S. Beà; S. Pittaluga; K. Dunleavy; W.H. Wilson; A. Wiestner, Blood, 2016 07 07, 128, 1, p.82-92, (2016) PubMed

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas., J. Bayliss; P. Mukherjee; C. Lu; S.U. Jain; C. Chung; D. Martinez; B. Sabari; A.S. Margol; P. Panwalkar; A. Parolia; M. Pekmezci; R.C. McEachin; M. Cieslik; B. Tamrazi; B.A. Garcia; G. La Rocca; M. Santi; P.W. Lewis; C. Hawkins; A. Melnick; D. Allis; C.B. Thompson; A.M. Chinnaiyan; A.R. Judkins; S. Venneti, Sci Transl Med, 2016 11 23, 8, 366, p.366ra161, (2016) PubMed

Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia., S. Li; F.E. Garrett-Bakelman; S.S. Chung; M.A. Sanders; T. Hricik; F. Rapaport; J. Patel; R. Dillon; P. Vijay; A.L. Brown; A.E. Perl; J. Cannon; L. Bullinger; S. Luger; M. Becker; I.D. Lewis; L.Bik To; R. Delwel; B. Löwenberg; H. Döhner; K. Döhner; M.L. Guzman; D.C. Hassane; G.J. Roboz; D. Grimwade; P.J.M. Valk; R.J. D'Andrea; M. Carroll; C.Y. Park; D. Neuberg; R. Levine; A.M. Melnick; C.E. Mason, Nat Med, 2016 07, 22, 7, p.792-9, (2016) PubMed