Found 17 results
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Journal Article
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q., Zhou, Li, Opalinska Joanna, Sohal Davendra, Yu Yiting, Mo Yongkai, Bhagat Tushar, Abdel-Wahab Omar, Fazzari Melissa, Figueroa Maria, Alencar Cristina, et al. , J Biol Chem, 2011 Jul 15, Volume 286, Issue 28, p.25211-23, (2011)
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900., Gönen, Mithat, Sun Zhuoxin, Figueroa Maria E., Patel Jay P., Abdel-Wahab Omar, Racevskis Janis, Ketterling Rhett P., Fernandez Hugo, Rowe Jacob M., Tallman Martin S., et al. , Blood, 2012 Sep 13, Volume 120, Issue 11, p.2297-306, (2012)
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL., Pastore, Alessandro, Gaiti Federico, Lu Sydney X., Brand Ryan M., Kulm Scott, Chaligne Ronan, Gu Hongcang, Huang Kevin Y., Stamenova Elena K., Béguelin Wendy, et al. , Nat Commun, 2019 Apr 23, Volume 10, Issue 1, p.1874, (2019)
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia., Rampal, Raajit, Alkalin Altuna, Madzo Jozef, Vasanthakumar Aparna, Pronier Elodie, Patel Jay, Li Yushan, Ahn Jihae, Abdel-Wahab Omar, Shih Alan, et al. , Cell Rep, 2014 Dec 11, Volume 9, Issue 5, p.1841-1855, (2014)
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling., Guryanova, Olga A., Shank Kaitlyn, Spitzer Barbara, Luciani Luisa, Koche Richard P., Garrett-Bakelman Francine E., Ganzel Chezi, Durham Benjamin H., Mohanty Abhinita, Hoermann Gregor, et al. , Nat Med, 2016 Dec, Volume 22, Issue 12, p.1488-1495, (2016)
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis., Béguelin, Wendy, Teater Matt, Gearhart Micah D., Fernández María Teresa Cal, Goldstein Rebecca L., Cardenas Mariano G., Hatzi Katerina, Rosen Monica, Shen Hao, Corcoran Connie M., et al. , Cancer Cell, 2016 Aug 08, Volume 30, Issue 2, p.197-213, (2016)
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation., Béguelin, Wendy, Popovic Relja, Teater Matt, Jiang Yanwen, Bunting Karen L., Rosen Monica, Shen Hao, Yang Shao Ning, Wang Ling, Ezponda Teresa, et al. , Cancer Cell, 2013 May 13, Volume 23, Issue 5, p.677-92, (2013)
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia., Chung, Stephen S., Kim Eunhee, Park Jae H., Chung Young Rock, Lito Piro, Teruya-Feldstein Julie, Hu Wenhuo, Béguelin Wendy, Monette Sebastien, Duy Cihangir, et al. , Sci Transl Med, 2014 May 28, Volume 6, Issue 238, p.238ra71, (2014)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
Loss of BAP1 function leads to EZH2-dependent transformation., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2015 Nov, Volume 21, Issue 11, p.1344-9, (2015)
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia., Patel, Jay P., Gönen Mithat, Figueroa Maria E., Fernandez Hugo, Sun Zhuoxin, Racevskis Janis, Van Vlierberghe Pieter, Dolgalev Igor, Thomas Sabrena, Aminova Olga, et al. , N Engl J Med, 2012 Mar 22, Volume 366, Issue 12, p.1079-89, (2012)
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML., Duy, Cihangir, Teater Matt, Garrett-Bakelman Francine E., Lee Tak C., Meydan Cem, Glass Jacob L., Li Meng, Hellmuth Johannes C., Mohammad Helai P., Smitheman Kimberly N., et al. , Cancer Discov, 2019 Jul, Volume 9, Issue 7, p.872-889, (2019)
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis., Busque, Lambert, Patel Jay P., Figueroa Maria E., Vasanthakumar Aparna, Provost Sylvie, Hamilou Zineb, Mollica Luigina, Li Juan, Viale Agnes, Heguy Adriana, et al. , Nat Genet, 2012 Nov, Volume 44, Issue 11, p.1179-81, (2012)
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2016 Jun 07, Volume 22, Issue 6, p.578-9, (2016)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Moran-Crusio, Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, et al. , Cancer Cell, 2011 Jul 12, Volume 20, Issue 1, p.11-24, (2011)