Found 20 results
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Journal Article
Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers., Bezdan, Daniela, Grigorev Kirill, Meydan Cem, Vatter Fanny A. Pelissie, Cioffi Michele, Rao Varsha, MacKay Matthew, Nakahira Kiichi, Burnham Philip, Afshinnekoo Ebrahim, et al. , iScience, 2020 Dec 18, Volume 23, Issue 12, p.101844, (2020)
Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence., Duy, Cihangir, Li Meng, Teater Matt, Meydan Cem, Garrett-Bakelman Francine E., Lee Tak C., Chin Christopher R., Durmaz Ceyda, Kawabata Kimihito C., Dhimolea Eugen, et al. , Cancer Discov, 2021 Jun, Volume 11, Issue 6, p.1542-1561, (2021)
Clonal Hematopoiesis Before, During, and After Human Spaceflight., Mencia-Trinchant, Nuria, MacKay Matthew J., Chin Christopher, Afshinnekoo Ebrahim, Foox Jonathan, Meydan Cem, Butler Daniel, Mozsary Christopher, Vernice Nicholas A., Darby Charlotte, et al. , Cell Rep, 2020 Dec 08, Volume 33, Issue 10, p.108458, (2020)
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 May, Volume 7, Issue 5, p.494-505, (2017)
Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity., Kunimoto, Hiroyoshi, Meydan Cem, Nazir Abbas, Whitfield Justin, Shank Kaitlyn, Rapaport Franck, Maher Rebecca, Pronier Elodie, Meyer Sara C., Garrett-Bakelman Francine E., et al. , Cancer Cell, 2018 Jan 08, Volume 33, Issue 1, p.44-59.e8, (2018)
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas., Jiang, Yanwen, Ortega-Molina Ana, Geng Huimin, Ying Hsia-Yuan, Hatzi Katerina, Parsa Sara, McNally Dylan, Wang Ling, Doane Ashley S., Agirre Xabier, et al. , Cancer Discov, 2017 Jan, Volume 7, Issue 1, p.38-53, (2017)
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis., Viny, Aaron D., Ott Christopher J., Spitzer Barbara, Rivas Martín, Meydan Cem, Papalexi Efthymia, Yelin Dana, Shank Kaitlyn, Reyes Jaime, Chiu April, et al. , J Exp Med, 2015 Oct 19, Volume 212, Issue 11, p.1819-32, (2015)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 Aug, Volume 7, Issue 8, p.868-883, (2017)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis., Hatzi, Katerina, Geng Huimin, Doane Ashley S., Meydan Cem, LaRiviere Reed, Cardenas Mariano, Duy Cihangir, Shen Hao, Vidal Maria Nieves Cal, Baslan Timour, et al. , Nat Immunol, 2019 Jan, Volume 20, Issue 1, p.86-96, (2019)
is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response., Agirre, Xabier, Meydan Cem, Jiang Yanwen, Garate Leire, Doane Ashley S., Li Zhuoning, Verma Akanksha, Paiva Bruno, Martín-Subero José I., Elemento Olivier, et al. , Nat Commun, 2019 Feb 18, Volume 10, Issue 1, p.821, (2019)
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., Béguelin, Wendy, Teater Matt, Meydan Cem, Hoehn Kenneth B., Phillip Jude M., Soshnev Alexey A., Venturutti Leandro, Rivas Martín A., Calvo-Fernández María T., Gutierrez Johana, et al. , Cancer Cell, 2020 May 11, Volume 37, Issue 5, p.655-673.e11, (2020)
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., Garrett-Bakelman, Francine E., Darshi Manjula, Green Stefan J., Gur Ruben C., Lin Ling, Macias Brandon R., McKenna Miles J., Meydan Cem, Mishra Tejaswini, Nasrini Jad, et al. , Science, 2019 Apr 12, Volume 364, Issue 6436, (2019)
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML., Duy, Cihangir, Teater Matt, Garrett-Bakelman Francine E., Lee Tak C., Meydan Cem, Glass Jacob L., Li Meng, Hellmuth Johannes C., Mohammad Helai P., Smitheman Kimberly N., et al. , Cancer Discov, 2019 Jul, Volume 9, Issue 7, p.872-889, (2019)
Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions., Butler, Daniel J., Mozsary Christopher, Meydan Cem, Danko David, Foox Jonathan, Rosiene Joel, Shaiber Alon, Afshinnekoo Ebrahim, MacKay Matthew, Sedlazeck Fritz J., et al. , bioRxiv, 2020 May 01, (2020)
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation., Rivas, Martín A., Meydan Cem, Chin Christopher R., Challman Matt F., Kim Daleum, Bhinder Bhavneet, Kloetgen Andreas, Viny Aaron D., Teater Matt R., McNally Dylan R., et al. , Nat Immunol, 2021 Feb, Volume 22, Issue 2, p.240-253, (2021)
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML., Li, Sheng, Chen Xiaowen, Wang Jiahui, Meydan Cem, Glass Jacob L., Shih Alan H., Delwel Ruud, Levine Ross L., Mason Christopher E., and Melnick Ari M. , Cancer Discov, 2020 Dec, Volume 10, Issue 12, p.1934-1949, (2020)