Found 11 results
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Journal Article
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia., Akalin, Altuna, Garrett-Bakelman Francine E., Kormaksson Matthias, Busuttil Jennifer, Zhang Lu, Khrebtukova Irina, Milne Thomas A., Huang Yongsheng, Biswas Debabrata, Hess Jay L., et al. , PLoS Genet, 2012, Volume 8, Issue 6, p.e1002781, (2012)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia., Li, Sheng, Garrett-Bakelman Francine E., Chung Stephen S., Sanders Mathijs A., Hricik Todd, Rapaport Franck, Patel Jay, Dillon Richard, Vijay Priyanka, Brown Anna L., et al. , Nat Med, 2016 Jul, Volume 22, Issue 7, p.792-9, (2016)
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia., Figueroa, Maria E., Lugthart Sanne, Li Yushan, Erpelinck-Verschueren Claudia, Deng Xutao, Christos Paul J., Schifano Elizabeth, Booth James, van Putten Wim, Skrabanek Lucy, et al. , Cancer Cell, 2010 Jan 19, Volume 17, Issue 1, p.13-27, (2010)
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia., Meyer, Sara E., Qin Tingting, Muench David E., Masuda Kohei, Venkatasubramanian Meenakshi, Orr Emily, Suarez Lauren, Gore Steven D., Delwel Ruud, Paietta Elisabeth, et al. , Cancer Discov, 2016 May, Volume 6, Issue 5, p.501-15, (2016)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 Aug, Volume 7, Issue 8, p.868-883, (2017)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia., Ribeiro, Ana Flávia Ti, Pratcorona Marta, Erpelinck-Verschueren Claudia, Rockova Veronika, Sanders Mathijs, Abbas Saman, Figueroa Maria E., Zeilemaker Annelieke, Melnick Ari, Löwenberg Bob, et al. , Blood, 2012 Jun 14, Volume 119, Issue 24, p.5824-31, (2012)
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML., Li, Sheng, Chen Xiaowen, Wang Jiahui, Meydan Cem, Glass Jacob L., Shih Alan H., Delwel Ruud, Levine Ross L., Mason Christopher E., and Melnick Ari M. , Cancer Discov, 2020 Dec, Volume 10, Issue 12, p.1934-1949, (2020)
Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling., Taskesen, Erdogan, Havermans Marije, van Lom Kirsten, Sanders Mathijs A., van Norden Yvette, Bindels Eric, Hoogenboezem Remco, Reinders Marcel J. T., Figueroa Maria E., Valk Peter J. M., et al. , Blood, 2014 May 22, Volume 123, Issue 21, p.3327-35, (2014)