Found 172 results
Filters: Author is Melnick, Ari  [Clear All Filters]
2020
Epigenetic Mechanisms in Leukemias and Lymphomas., Duy, Cihangir, Béguelin Wendy, and Melnick Ari , Cold Spring Harb Perspect Med, 2020 Dec 01, Volume 10, Issue 12, (2020)
2018
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis., Teater, Matt, Dominguez Pilar M., Redmond David, Chen Zhengming, Ennishi Daisuke, Scott David W., Cimmino Luisa, Ghione Paola, Chaudhuri Jayanta, Gascoyne Randy D., et al. , Nat Commun, 2018 Jan 15, Volume 9, Issue 1, p.222, (2018)
Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity., Kunimoto, Hiroyoshi, Meydan Cem, Nazir Abbas, Whitfield Justin, Shank Kaitlyn, Rapaport Franck, Maher Rebecca, Pronier Elodie, Meyer Sara C., Garrett-Bakelman Francine E., et al. , Cancer Cell, 2018 Jan 08, Volume 33, Issue 1, p.44-59.e8, (2018)
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis., Pronier, Elodie, Bowman Robert L., Ahn Jihae, Glass Jacob, Kandoth Cyriac, Merlinsky Tiffany R., Whitfield Justin T., Durham Benjamin H., Gruet Antoine, Somasundara Amritha Varshini H., et al. , Blood, 2018 Sep 20, Volume 132, Issue 12, p.1265-1278, (2018)
Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design., Cheng, Huimin, Linhares Brian M., Yu Wenbo, Cardenas Mariano G., Ai Yong, Jiang Wenjuan, Winkler Alyssa, Cohen Sandra, Melnick Ari, MacKerell Alexander, et al. , J Med Chem, 2018 Sep 13, Volume 61, Issue 17, p.7573-7588, (2018)
MEF2C Phosphorylation Is Required for Chemotherapy Resistance in Acute Myeloid Leukemia., Brown, Fiona C., Still Eric, Koche Richard P., Yim Christina Y., Takao Sumiko, Cifani Paolo, Reed Casie, Gunasekera Shehana, Ficarro Scott B., Romanienko Peter, et al. , Cancer Discov, 2018 Apr, Volume 8, Issue 4, p.478-497, (2018)
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia., Maes, Tamara, Mascaró Cristina, Tirapu Iñigo, Estiarte Angels, Ciceri Filippo, Lunardi Serena, Guibourt Nathalie, Perdones Alvaro, Lufino Michele M. P., Somervaille Tim C. P., et al. , Cancer Cell, 2018 Mar 12, Volume 33, Issue 3, p.495-511.e12, (2018)
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth., Fontan, Lorena, Qiao Qi, Hatcher John M., Casalena Gabriella, Us Ilkay, Teater Matt, Durant Matt, Du Guangyan, Xia Min, Bilchuk Natalia, et al. , J Clin Invest, 2018 Oct 01, Volume 128, Issue 10, p.4397-4412, (2018)
Untangling the Role of Polycomb Complexes in Chemotherapy Resistance., Duy, Cihangir, and Melnick Ari , Cancer Discov, 2018 Nov, Volume 8, Issue 11, p.1348-1351, (2018)
2017
BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells., Valls, Ester, Lobry Camille, Geng Huimin, Wang Ling, Cardenas Mariano, Rivas Martín, Cerchietti Leandro, Oh Philmo, Yang Shao Ning, Oswald Erin, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.506-521, (2017)
Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury., Li, Yong, Huang Xuan, Huang Shengping, He Hui, Lei Tianhua, Saaoud Fatma, Yu Xiao-Qiang, Melnick Ari, Kumar Anil, Papasian Christopher J., et al. , Signal Transduct Target Ther, 2017, Volume 2, p.17066, (2017)
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.494-505, (2017)
DNA Methylation-Based Biomarkers., Cerchietti, Leandro, and Melnick Ari , J Clin Oncol, 2017 03, Volume 35, Issue 7, p.793-795, (2017)
Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model., Du, Wei, Goldstein Rebecca, Jiang Yanwen, Aly Omar, Cerchietti Leandro, Melnick Ari, and Elemento Olivier , Cancer Res, 2017 04 15, Volume 77, Issue 8, p.1818-1830, (2017)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 08, Volume 7, Issue 8, p.868-883, (2017)
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., Gascoyne, Randy D., Nadel Bertrand, Pasqualucci Laura, Fitzgibbon Jude, Payton Jacqueline E., Melnick Ari, Weigert Oliver, Tarte Karin, Gribben John G., Friedberg Jonathan W., et al. , Hematol Oncol, 2017 Dec, Volume 35, Issue 4, p.397-407, (2017)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 12 15, Volume 77, Issue 24, p.7038-7048, (2017)
The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells., Vu, Ly P., Pickering Brian F., Cheng Yuanming, Zaccara Sara, Nguyen Diu, Minuesa Gerard, Chou Timothy, Chow Arthur, Saletore Yogesh, MacKay Matthew, et al. , Nat Med, 2017 Nov, Volume 23, Issue 11, p.1369-1376, (2017)