Found 18 results
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Journal Article
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity., De, Subhajyoti, Shaknovich Rita, Riester Markus, Elemento Olivier, Geng Huimin, Kormaksson Matthias, Jiang Yanwen, Woolcock Bruce, Johnson Nathalie, Polo Jose M., et al. , PLoS Genet, 2013, Volume 9, Issue 1, p.e1003137, (2013)
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR., Ranuncolo, Stella Maris, Polo Jose M., Dierov Jamil, Singer Michael, Kuo Tracy, Greally John, Green Roland, Carroll Martin, and Melnick Ari , Nat Immunol, 2007 Jul, Volume 8, Issue 7, p.705-14, (2007)
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL., Pastore, Alessandro, Gaiti Federico, Lu Sydney X., Brand Ryan M., Kulm Scott, Chaligne Ronan, Gu Hongcang, Huang Kevin Y., Stamenova Elena K., Béguelin Wendy, et al. , Nat Commun, 2019 Apr 23, Volume 10, Issue 1, p.1874, (2019)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 Oct 12, Volume 8, Issue 1, p.877, (2017)
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis., Velichutina, Irina, Shaknovich Rita, Geng Huimin, Johnson Nathalie A., Gascoyne Randy D., Melnick Ari M., and Elemento Olivier , Blood, 2010 Dec 09, Volume 116, Issue 24, p.5247-55, (2010)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT., Takahashi, Shinichiro, McConnell Melanie J., Harigae Hideo, Kaku Mitsuo, Sasaki Takeshi, Melnick Ari M., and Licht Jonathan D. , Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)
Genetic and epigenetic inactivation of controls mTORC1 and response to EZH2 inhibition in follicular lymphoma., Oricchio, Elisa, Katanayeva Natalya, Donaldson Maria Christine, Sungalee Stephanie, Pasion Joyce P., Béguelin Wendy, Battistello Elena, Sanghvi Viraj R., Jiang Man, Jiang Yanwen, et al. , Sci Transl Med, 2017 Jun 28, Volume 9, Issue 396, (2017)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture., Yusufova, Nevin, Kloetgen Andreas, Teater Matt, Osunsade Adewola, Camarillo Jeannie M., Chin Christopher R., Doane Ashley S., Venters Bryan J., Portillo-Ledesma Stephanie, Conway Joseph, et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.299-305, (2021)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)
The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 Jul, Volume 23, Issue 4, p.377-84, (2016)
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting., Schafer, Eric, Irizarry Rafael, Negi Sandeep, McIntyre Emily, Small Donald, Figueroa Maria E., Melnick Ari, and Brown Patrick , Blood, 2010 Jun 10, Volume 115, Issue 23, p.4798-809, (2010)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Moran-Crusio, Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, et al. , Cancer Cell, 2011 Jul 12, Volume 20, Issue 1, p.11-24, (2011)
The theoretical basis of transcriptional therapy of cancer: can it be put into practice?, Melnick, Ari M., Adelson Kerin, and Licht Jonathan D. , J Clin Oncol, 2005 Jun 10, Volume 23, Issue 17, p.3957-70, (2005)