Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization., Gomes, Ana P., Ilter Didem, Low Vivien, Rosenzweig Adam, Shen Zih-Jie, Schild Tanya, Rivas Martín A., Er Ekrem E., McNally Dylan R., Mutvei Anders P., et al. , Cancer Cell, 2019 Oct 14, Volume 36, Issue 4, p.402-417.e13, (2019)

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 Jun 14, Volume 7, p.11889, (2016)

Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers., Agirre, Xabier, Castellano Giancarlo, Pascual Marien, Heath Simon, Kulis Marta, Segura Victor, Bergmann Anke, Esteve Anna, Merkel Angelika, Raineri Emanuele, et al. , Genome Res, 2015 Apr, Volume 25, Issue 4, p.478-87, (2015)

Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)

DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation., Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al. , Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)

Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)

PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex., Vu, Ly P., Perna Fabiana, Wang Lan, Voza Francesca, Figueroa Maria E., Tempst Paul, Erdjument-Bromage Hediye, Gao Rui, Chen Sisi, Paietta Elisabeth, et al. , Cell Rep, 2013 Dec 26, Volume 5, Issue 6, p.1625-38, (2013)

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis., Sun, Xiao-Jian, Wang Zhanxin, Wang Lan, Jiang Yanwen, Kost Nils, T Soong David, Chen Wei-Yi, Tang Zhanyun, Nakadai Tomoyoshi, Elemento Olivier, et al. , Nature, 2013 Aug 01, Volume 500, Issue 7460, p.93-7, (2013)

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)

H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia., Kawahara, Masahiro, Pandolfi Ashley, Bartholdy Boris, Barreyro Laura, Will Britta, Roth Michael, Okoye-Okafor Ujunwa C., Todorova Tihomira I., Figueroa Maria E., Melnick Ari, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.194-208, (2012)

A molecular roadmap of reprogramming somatic cells into iPS cells., Polo, Jose M., Anderssen Endre, Walsh Ryan M., Schwarz Benjamin A., Nefzger Christian M., Lim Sue Mei, Borkent Marti, Apostolou Effie, Alaei Sara, Cloutier Jennifer, et al. , Cell, 2012 Dec 21, Volume 151, Issue 7, p.1617-32, (2012)

EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis., Velichutina, Irina, Shaknovich Rita, Geng Huimin, Johnson Nathalie A., Gascoyne Randy D., Melnick Ari M., and Elemento Olivier , Blood, 2010 Dec 09, Volume 116, Issue 24, p.5247-55, (2010)

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis., Murphy, Mark W., Sarver Aaron L., Rice Daren, Hatzi Katerina, Ye Kenny, Melnick Ari, Heckert Leslie L., Zarkower David, and Bardwell Vivian J. , Proc Natl Acad Sci U S A, 2010 Jul 27, Volume 107, Issue 30, p.13360-5, (2010)

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)

Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)

Sequential transcription factor targeting for diffuse large B-cell lymphomas., Cerchietti, Leandro C., Polo Jose M., Da Silva Gustavo F., Farinha Pedro, Shaknovich Rita, Gascoyne Randy D., Dowdy Steven F., and Melnick Ari , Cancer Res, 2008 May 01, Volume 68, Issue 9, p.3361-9, (2008)

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms., Parekh, Samir, Polo Jose M., Shaknovich Rita, Juszczynski Przemyslaw, Lev Paola, Ranuncolo Stella M., Yin Yingnan, Klein Ulf, Cattoretti Giorgio, Favera Riccardo Dalla, et al. , Blood, 2007 Sep 15, Volume 110, Issue 6, p.2067-74, (2007)

Kaiso-deficient mice show resistance to intestinal cancer., Prokhortchouk, Anna, Sansom Owen, Selfridge Jim, Caballero Isabel M., Salozhin Sergey, Aithozhina Dana, Cerchietti Leandro, Meng Fan Guo, Augenlicht Leonard H., Mariadason John M., et al. , Mol Cell Biol, 2006 Jan, Volume 26, Issue 1, p.199-208, (2006)

ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein., Chevallier, Nathalie, Corcoran Connie M., Lennon Christine, Hyjek Elizabeth, Chadburn Amy, Bardwell Vivian J., Licht Jonathan D., and Melnick Ari , Blood, 2004 Feb 15, Volume 103, Issue 4, p.1454-63, (2004)

The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT., Takahashi, Shinichiro, McConnell Melanie J., Harigae Hideo, Kaku Mitsuo, Sasaki Takeshi, Melnick Ari M., and Licht Jonathan D. , Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)

Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain., K Ahmad, Farid, Melnick Ari, Lax Stuart, Bouchard Denis, Liu Jun, Kiang Chih-Li, Mayer Sebastian, Takahashi Shinichiro, Licht Jonathan D., and Prive Gilbert G. , Mol Cell, 2003 Dec, Volume 12, Issue 6, p.1551-64, (2003)

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors., Melnick, Ari, Carlile Graeme, K Ahmad Farid, Kiang Chih-Li, Corcoran Connie, Bardwell Vivian, Prive Gilbert G., and Licht Jonathan D. , Mol Cell Biol, 2002 Mar, Volume 22, Issue 6, p.1804-18, (2002)

AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein., Melnick, A, Carlile G W., McConnell M J., Polinger A, Hiebert S W., and Licht J D. , Blood, 2000 Dec 01, Volume 96, Issue 12, p.3939-47, (2000)