Found 31 results
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Journal Article
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein., Melnick, A, Carlile G W., McConnell M J., Polinger A, Hiebert S W., and Licht J D. , Blood, 2000 Dec 01, Volume 96, Issue 12, p.3939-47, (2000)
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms., Parekh, Samir, Polo Jose M., Shaknovich Rita, Juszczynski Przemyslaw, Lev Paola, Ranuncolo Stella M., Yin Yingnan, Klein Ulf, Cattoretti Giorgio, Favera Riccardo Dalla, et al. , Blood, 2007 Sep 15, Volume 110, Issue 6, p.2067-74, (2007)
Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors., Melnick, Ari, Carlile Graeme, K Ahmad Farid, Kiang Chih-Li, Corcoran Connie, Bardwell Vivian, Prive Gilbert G., and Licht Jonathan D. , Mol Cell Biol, 2002 Mar, Volume 22, Issue 6, p.1804-18, (2002)
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia., Melnick, A, and Licht J D. , Blood, 1999 May 15, Volume 93, Issue 10, p.3167-215, (1999)
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation., Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al. , Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization., Gomes, Ana P., Ilter Didem, Low Vivien, Rosenzweig Adam, Shen Zih-Jie, Schild Tanya, Rivas Martín A., Er Ekrem E., McNally Dylan R., Mutvei Anders P., et al. , Cancer Cell, 2019 Oct 14, Volume 36, Issue 4, p.402-417.e13, (2019)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein., Melnick, A M., Westendorf J J., Polinger A, Carlile G W., Arai S, Ball H J., Lutterbach B, Hiebert S W., and Licht J D. , Mol Cell Biol, 2000 Mar, Volume 20, Issue 6, p.2075-86, (2000)
ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein., Chevallier, Nathalie, Corcoran Connie M., Lennon Christine, Hyjek Elizabeth, Chadburn Amy, Bardwell Vivian J., Licht Jonathan D., and Melnick Ari , Blood, 2004 Feb 15, Volume 103, Issue 4, p.1454-63, (2004)
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis., Velichutina, Irina, Shaknovich Rita, Geng Huimin, Johnson Nathalie A., Gascoyne Randy D., Melnick Ari M., and Elemento Olivier , Blood, 2010 Dec 09, Volume 116, Issue 24, p.5247-55, (2010)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT., Takahashi, Shinichiro, McConnell Melanie J., Harigae Hideo, Kaku Mitsuo, Sasaki Takeshi, Melnick Ari M., and Licht Jonathan D. , Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis., Murphy, Mark W., Sarver Aaron L., Rice Daren, Hatzi Katerina, Ye Kenny, Melnick Ari, Heckert Leslie L., Zarkower David, and Bardwell Vivian J. , Proc Natl Acad Sci U S A, 2010 Jul 27, Volume 107, Issue 30, p.13360-5, (2010)
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia., Kawahara, Masahiro, Pandolfi Ashley, Bartholdy Boris, Barreyro Laura, Will Britta, Roth Michael, Okoye-Okafor Ujunwa C., Todorova Tihomira I., Figueroa Maria E., Melnick Ari, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.194-208, (2012)
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 Jun 14, Volume 7, p.11889, (2016)
In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions., Melnick, A, Ahmad K F., Arai S, Polinger A, Ball H, Borden K L., Carlile G W., Prive G G., and Licht J D. , Mol Cell Biol, 2000 Sep, Volume 20, Issue 17, p.6550-67, (2000)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
Kaiso-deficient mice show resistance to intestinal cancer., Prokhortchouk, Anna, Sansom Owen, Selfridge Jim, Caballero Isabel M., Salozhin Sergey, Aithozhina Dana, Cerchietti Leandro, Meng Fan Guo, Augenlicht Leonard H., Mariadason John M., et al. , Mol Cell Biol, 2006 Jan, Volume 26, Issue 1, p.199-208, (2006)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain., K Ahmad, Farid, Melnick Ari, Lax Stuart, Bouchard Denis, Liu Jun, Kiang Chih-Li, Mayer Sebastian, Takahashi Shinichiro, Licht Jonathan D., and Prive Gilbert G. , Mol Cell, 2003 Dec, Volume 12, Issue 6, p.1551-64, (2003)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
A molecular roadmap of reprogramming somatic cells into iPS cells., Polo, Jose M., Anderssen Endre, Walsh Ryan M., Schwarz Benjamin A., Nefzger Christian M., Lim Sue Mei, Borkent Marti, Apostolou Effie, Alaei Sara, Cloutier Jennifer, et al. , Cell, 2012 Dec 21, Volume 151, Issue 7, p.1617-32, (2012)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF., Hoatlin, M E., Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, et al. , Blood, 1999 Dec 01, Volume 94, Issue 11, p.3737-47, (1999)