Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation., Rivas, Martín A., Meydan Cem, Chin Christopher R., Challman Matt F., Kim Daleum, Bhinder Bhavneet, Kloetgen Andreas, Viny Aaron D., Teater Matt R., McNally Dylan R., et al. , Nat Immunol, 2021 02, Volume 22, Issue 2, p.240-253, (2021)

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., Fabre, Marie-Sophie, Stanton Nicole M., Slatter Tania L., Lee Samuel, Senanayake Dinindu, Gordon Rosemary M. A., M Castro Leticia, Rowe Matthew R., Taha Ahmad, Royds Janice A., et al. , PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)

Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma., Mondello, Patrizia, Tadros Saber, Teater Matt, Fontan Lorena, Chang Aaron Y., Jain Neeraj, Yang Haopeng, Singh Shailbala, Ying Hsia-Yuan, Chu Chi-Shuen, et al. , Cancer Discov, 2020 03, Volume 10, Issue 3, p.440-459, (2020)

Germinal center-derived lymphomas: The darkest side of humoral immunity., Mlynarczyk, Coraline, Fontan Lorena, and Melnick Ari , Immunol Rev, 2019 03, Volume 288, Issue 1, p.214-239, (2019)

Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., Li, Meng, Chiang Ying-Ling, Lyssiotis Costas A., Teater Matthew R., Hong Jun Young, Shen Hao, Wang Ling, Hu Jing, Jing Hui, Chen Zhengming, et al. , Cancer Cell, 2019 06 10, Volume 35, Issue 6, p.916-931.e9, (2019)

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity., Kunimoto, Hiroyoshi, Meydan Cem, Nazir Abbas, Whitfield Justin, Shank Kaitlyn, Rapaport Franck, Maher Rebecca, Pronier Elodie, Meyer Sara C., Garrett-Bakelman Francine E., et al. , Cancer Cell, 2018 01 08, Volume 33, Issue 1, p.44-59.e8, (2018)

How Biophysical Forces Regulate Human B Cell Lymphomas., Apoorva, F, Loiben Alexander M., Shah Shivem B., Purwada Alberto, Fontan Lorena, Goldstein Rebecca, Kirby Brian J., Melnick Ari M., Cosgrove Benjamin D., and Singh Ankur , Cell Rep, 2018 Apr 10, Volume 23, Issue 2, p.499-511, (2018)

Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth., Fontan, Lorena, Qiao Qi, Hatcher John M., Casalena Gabriella, Us Ilkay, Teater Matt, Durant Matt, Du Guangyan, Xia Min, Bilchuk Natalia, et al. , J Clin Invest, 2018 10 01, Volume 128, Issue 10, p.4397-4412, (2018)

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.494-505, (2017)

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model., Du, Wei, Goldstein Rebecca, Jiang Yanwen, Aly Omar, Cerchietti Leandro, Melnick Ari, and Elemento Olivier , Cancer Res, 2017 04 15, Volume 77, Issue 8, p.1818-1830, (2017)

Untangling the Web of Lymphoma Somatic Mutations., Teater, Matt, and Melnick Ari , Cell, 2017 10 05, Volume 171, Issue 2, p.270-272, (2017)

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 06 14, Volume 7, p.11889, (2016)

The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 07, Volume 23, Issue 4, p.377-84, (2016)

miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis., Kozloski, Goldi A., Jiang Xiaoyu, Bhatt Shruti, Ruiz Jose, Vega Francisco, Shaknovich Rita, Melnick Ari, and Lossos Izidore S. , Blood, 2016 06 09, Volume 127, Issue 23, p.2856-66, (2016)

Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma., Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al. , Blood, 2016 07 07, Volume 128, Issue 1, p.82-92, (2016)

PTEN opposes negative selection and enables oncogenic transformation of pre-B cells., Shojaee, Seyedmehdi, Chan Lai N., Buchner Maike, Cazzaniga Valeria, Cosgun Kadriye Nehir, Geng Huimin, Qiu Yi Hua, von Minden Marcus Dühren, Ernst Thomas, Hochhaus Andreas, et al. , Nat Med, 2016 Apr, Volume 22, Issue 4, p.379-87, (2016)

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species., Zong, Hongliang, Gozman Alexander, Caldas-Lopes Eloisi, Taldone Tony, Sturgill Eric, Brennan Sarah, Ochiana Stefan O., Gomes-DaGama Erica M., Sen Siddhartha, Rodina Anna, et al. , Cell Rep, 2015 Dec 15, Volume 13, Issue 10, p.2159-73, (2015)

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., Buchner, Maike, Park Eugene, Geng Huimin, Klemm Lars, Flach Johanna, Passegué Emmanuelle, Schjerven Hilde, Melnick Ari, Paietta Elisabeth, Kopanja Dragana, et al. , Nat Commun, 2015 Mar 10, Volume 6, p.6471, (2015)

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Tian, Ye F., Ahn Haelee, Schneider Rebecca S., Yang Shao Ning, Roman-Gonzalez Lidia, Melnick Ari M., Cerchietti Leandro, and Singh Ankur , Biomaterials, 2015 Dec, Volume 73, p.110-9, (2015)

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al. , J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia., Geng, Huimin, Hurtz Christian, Lenz Kyle B., Chen Zhengshan, Baumjohann Dirk, Thompson Sarah, Goloviznina Natalya A., Chen Wei-Yi, Huan Jianya, LaTocha Dorian, et al. , Cancer Cell, 2015 Mar 09, Volume 27, Issue 3, p.409-25, (2015)

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters., Hatzi, Katerina, Jiang Yanwen, Huang ChuanXin, Garrett-Bakelman Francine, Gearhart Micah D., Giannopoulou Eugenia G., Zumbo Paul, Kirouac Kevin, Bhaskara Srividya, Polo Jose M., et al. , Cell Rep, 2013 Aug 15, Volume 4, Issue 3, p.578-88, (2013)

Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes., Ruan, Jia, Luo Min, Wang Chunjie, Fan Lei, Yang Shao Ning, Cardenas Mariano, Geng Huimin, Leonard John P., Melnick Ari, Cerchietti Leandro, et al. , Blood, 2013 Jun 27, Volume 121, Issue 26, p.5192-202, (2013)

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia., Figueroa, Maria E., Chen Shann-Ching, Andersson Anna K., Phillips Letha A., Li Yushan, Sotzen Jason, Kundu Mondira, Downing James R., Melnick Ari, and Mullighan Charles G. , J Clin Invest, 2013 Jul, Volume 123, Issue 7, p.3099-111, (2013)

Molecular pathways: targeting MALT1 paracaspase activity in lymphoma., Fontan, Lorena, and Melnick Ari , Clin Cancer Res, 2013 Dec 15, Volume 19, Issue 24, p.6662-8, (2013)