Found 132 results
Filters: Keyword is Animals  [Clear All Filters]
2021
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities., Flümann, Ruth, Rehkämper Tim, Nieper Pascal, Pfeiffer Pauline, Holzem Alessandra, Klein Sebastian, Bhatia Sanil, Kochanek Moritz, Kisis Ilmars, Pelzer Benedikt W., et al. , Blood Cancer Discov, 2021 01, Volume 2, Issue 1, p.70-91, (2021)
Chemotherapy Induces Senescence-Like Resilient Cells Capable of Initiating AML Recurrence., Duy, Cihangir, Li Meng, Teater Matt, Meydan Cem, Garrett-Bakelman Francine E., Lee Tak C., Chin Christopher R., Durmaz Ceyda, Kawabata Kimihito C., Dhimolea Eugen, et al. , Cancer Discov, 2021 06, Volume 11, Issue 6, p.1542-1561, (2021)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 01, Volume 589, Issue 7841, p.293-298, (2021)
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture., Yusufova, Nevin, Kloetgen Andreas, Teater Matt, Osunsade Adewola, Camarillo Jeannie M., Chin Christopher R., Doane Ashley S., Venters Bryan J., Portillo-Ledesma Stephanie, Conway Joseph, et al. , Nature, 2021 01, Volume 589, Issue 7841, p.299-305, (2021)
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation., Rivas, Martín A., Meydan Cem, Chin Christopher R., Challman Matt F., Kim Daleum, Bhinder Bhavneet, Kloetgen Andreas, Viny Aaron D., Teater Matt R., McNally Dylan R., et al. , Nat Immunol, 2021 02, Volume 22, Issue 2, p.240-253, (2021)
2020
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., Béguelin, Wendy, Teater Matt, Meydan Cem, Hoehn Kenneth B., Phillip Jude M., Soshnev Alexey A., Venturutti Leandro, Rivas Martín A., Calvo-Fernández María T., Gutierrez Johana, et al. , Cancer Cell, 2020 05 11, Volume 37, Issue 5, p.655-673.e11, (2020)
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., Fabre, Marie-Sophie, Stanton Nicole M., Slatter Tania L., Lee Samuel, Senanayake Dinindu, Gordon Rosemary M. A., M Castro Leticia, Rowe Matthew R., Taha Ahmad, Royds Janice A., et al. , PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)
Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma., Mondello, Patrizia, Tadros Saber, Teater Matt, Fontan Lorena, Chang Aaron Y., Jain Neeraj, Yang Haopeng, Singh Shailbala, Ying Hsia-Yuan, Chu Chi-Shuen, et al. , Cancer Discov, 2020 03, Volume 10, Issue 3, p.440-459, (2020)
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate., Venturutti, Leandro, Teater Matt, Zhai Andrew, Chadburn Amy, Babiker Leena, Kim Daleum, Béguelin Wendy, Lee Tak C., Kim Youngjun, Chin Christopher R., et al. , Cell, 2020 07 23, Volume 182, Issue 2, p.297-316.e27, (2020)
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage., Chu, Chi-Shuen, Hellmuth Johannes C., Singh Rajat, Ying Hsia-Yuan, Skrabanek Lucy, Teater Matthew R., Doane Ashley S., Elemento Olivier, Melnick Ari M., and Roeder Robert G. , Mol Cell, 2020 12 03, Volume 80, Issue 5, p.845-861.e10, (2020)
2019
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress., Fernando, Tharu M., Marullo Rossella, Gresely Benet Pera, Phillip Jude M., Yang Shao Ning, Lundell-Smith Geoffrey, Torregroza Ingrid, Ahn Haelee, Evans Todd, Gyorffy Balazs, et al. , Cancer Discov, 2019 05, Volume 9, Issue 5, p.662-679, (2019)
BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection., Zhu, Bibo, Zhang Ruixuan, Li Chaofan, Jiang Li, Xiang Min, Ye Zhenqing, Kita Hirohito, Melnick Ari M., Dent Alexander L., and Sun Jie , Proc Natl Acad Sci U S A, 2019 06 11, Volume 116, Issue 24, p.11888-11893, (2019)
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization., Gomes, Ana P., Ilter Didem, Low Vivien, Rosenzweig Adam, Shen Zih-Jie, Schild Tanya, Rivas Martín A., Er Ekrem E., McNally Dylan R., Mutvei Anders P., et al. , Cancer Cell, 2019 10 14, Volume 36, Issue 4, p.402-417.e13, (2019)
Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells., Purwada, Alberto, Shah Shivem B., Béguelin Wendy, August Avery, Melnick Ari M., and Singh Ankur , Biomaterials, 2019 04, Volume 198, p.27-36, (2019)
An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming?, Li, Meng, and Melnick Ari M. , Cancer Discov, 2019 Sep, Volume 9, Issue 9, p.1158-1160, (2019)
Germinal center-derived lymphomas: The darkest side of humoral immunity., Mlynarczyk, Coraline, Fontan Lorena, and Melnick Ari , Immunol Rev, 2019 03, Volume 288, Issue 1, p.214-239, (2019)
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis., Hatzi, Katerina, Geng Huimin, Doane Ashley S., Meydan Cem, LaRiviere Reed, Cardenas Mariano, Duy Cihangir, Shen Hao, Vidal Maria Nieves Cal, Baslan Timour, et al. , Nat Immunol, 2019 01, Volume 20, Issue 1, p.86-96, (2019)
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition., Ennishi, Daisuke, Takata Katsuyoshi, Béguelin Wendy, Duns Gerben, Mottok Anja, Farinha Pedro, Bashashati Ali, Saberi Saeed, Boyle Merrill, Meissner Barbara, et al. , Cancer Discov, 2019 04, Volume 9, Issue 4, p.546-563, (2019)
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., Lu, Xiangdong, Chu Chi-Shuen, Fang Terry, Rayon-Estrada Violeta, Fang Fang, Patke Alina, Qian Ye, Clarke Stephen H., Melnick Ari M., Zhang Yi, et al. , Cell Rep, 2019 07 09, Volume 28, Issue 2, p.472-485.e5, (2019)
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., Li, Meng, Chiang Ying-Ling, Lyssiotis Costas A., Teater Matthew R., Hong Jun Young, Shen Hao, Wang Ling, Hu Jing, Jing Hui, Chen Zhengming, et al. , Cancer Cell, 2019 06 10, Volume 35, Issue 6, p.916-931.e9, (2019)
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas., Pascual, Marien, Mena-Varas Maria, Robles Eloy Francisco, Garcia-Barchino Maria-Jose, Panizo Carlos, Hervas-Stubbs Sandra, Alignani Diego, Sagardoy Ainara, Martinez-Ferrandis Jose Ignacio, Bunting Karen L., et al. , Blood, 2019 05 30, Volume 133, Issue 22, p.2401-2412, (2019)
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML., Duy, Cihangir, Teater Matt, Garrett-Bakelman Francine E., Lee Tak C., Meydan Cem, Glass Jacob L., Li Meng, Hellmuth Johannes C., Mohammad Helai P., Smitheman Kimberly N., et al. , Cancer Discov, 2019 07, Volume 9, Issue 7, p.872-889, (2019)
Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease., Paz, Katelyn, Flynn Ryan, Du Jing, Qi Jun, Luznik Leo, Maillard Ivan, MacDonald Kelli P., Hill Geoffrey R., Serody Jonathan S., Murphy William J., et al. , Blood, 2019 01 03, Volume 133, Issue 1, p.94-99, (2019)