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Journal Article
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q., Zhou, Li, Opalinska Joanna, Sohal Davendra, Yu Yiting, Mo Yongkai, Bhagat Tushar, Abdel-Wahab Omar, Fazzari Melissa, Figueroa Maria, Alencar Cristina, et al. , J Biol Chem, 2011 Jul 15, Volume 286, Issue 28, p.25211-23, (2011)
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress., Fernando, Tharu M., Marullo Rossella, Gresely Benet Pera, Phillip Jude M., Yang Shao Ning, Lundell-Smith Geoffrey, Torregroza Ingrid, Ahn Haelee, Evans Todd, Gyorffy Balazs, et al. , Cancer Discov, 2019 May, Volume 9, Issue 5, p.662-679, (2019)
BCL6 is critical for the development of a diverse primary B cell repertoire., Duy, Cihangir, J Yu Jessica, Nahar Rahul, Swaminathan Srividya, Kweon Soo-Mi, Polo Jose M., Valls Ester, Klemm Lars, Shojaee Seyedmehdi, Cerchietti Leandro, et al. , J Exp Med, 2010 Jun 07, Volume 207, Issue 6, p.1209-21, (2010)
BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection., Zhu, Bibo, Zhang Ruixuan, Li Chaofan, Jiang Li, Xiang Min, Ye Zhenqing, Kita Hirohito, Melnick Ari M., Dent Alexander L., and Sun Jie , Proc Natl Acad Sci U S A, 2019 Jun 11, Volume 116, Issue 24, p.11888-11893, (2019)
CD99 is a therapeutic target on disease stem cells in myeloid malignancies., Chung, Stephen S., Eng William S., Hu Wenhuo, Khalaj Mona, Garrett-Bakelman Francine E., Tavakkoli Montreh, Levine Ross L., Carroll Martin, Klimek Virginia M., Melnick Ari M., et al. , Sci Transl Med, 2017 Jan 25, Volume 9, Issue 374, (2017)
HDAC4 promotes growth of colon cancer cells via repression of p21., Wilson, Andrew J., Byun Do-Sun, Nasser Shannon, Murray Lucas B., Ayyanar Kanyalakshmi, Arango Diego, Figueroa Maria, Melnick Ari, Kao Gary D., Augenlicht Leonard H., et al. , Mol Biol Cell, 2008 Oct, Volume 19, Issue 10, p.4062-75, (2008)
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells., Ha, Kyungsoo, Fiskus Warren, Choi Dong Soon, Bhaskara Srividya, Cerchietti Leandro, Devaraj Santhana G. T., Shah Bhavin, Sharma Sunil, Chang Jenny C., Melnick Ari M., et al. , Oncotarget, 2014 Jul 30, Volume 5, Issue 14, p.5637-50, (2014)
How Biophysical Forces Regulate Human B Cell Lymphomas., Apoorva, F, Loiben Alexander M., Shah Shivem B., Purwada Alberto, Fontan Lorena, Goldstein Rebecca, Kirby Brian J., Melnick Ari M., Cosgrove Benjamin D., and Singh Ankur , Cell Rep, 2018 Apr 10, Volume 23, Issue 2, p.499-511, (2018)
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species., Zong, Hongliang, Gozman Alexander, Caldas-Lopes Eloisi, Taldone Tony, Sturgill Eric, Brennan Sarah, Ochiana Stefan O., Gomes-DaGama Erica M., Sen Siddhartha, Rodina Anna, et al. , Cell Rep, 2015 Dec 15, Volume 13, Issue 10, p.2159-73, (2015)
Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes., Ruan, Jia, Luo Min, Wang Chunjie, Fan Lei, Yang Shao Ning, Cardenas Mariano, Geng Huimin, Leonard John P., Melnick Ari, Cerchietti Leandro, et al. , Blood, 2013 Jun 27, Volume 121, Issue 26, p.5192-202, (2013)
Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Tian, Ye F., Ahn Haelee, Schneider Rebecca S., Yang Shao Ning, Roman-Gonzalez Lidia, Melnick Ari M., Cerchietti Leandro, and Singh Ankur , Biomaterials, 2015 Dec, Volume 73, p.110-9, (2015)
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 Dec 15, Volume 77, Issue 24, p.7038-7048, (2017)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia., Maes, Tamara, Mascaró Cristina, Tirapu Iñigo, Estiarte Angels, Ciceri Filippo, Lunardi Serena, Guibourt Nathalie, Perdones Alvaro, Lufino Michele M. P., Somervaille Tim C. P., et al. , Cancer Cell, 2018 Mar 12, Volume 33, Issue 3, p.495-511.e12, (2018)
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma., Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al. , Blood, 2016 Jul 07, Volume 128, Issue 1, p.82-92, (2016)
Reprogramming specific gene expression pathways in B-cell lymphomas., Melnick, Ari , Cell Cycle, 2005 Feb, Volume 4, Issue 2, p.239-41, (2005)
SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells., Hammerich-Hille, Stephanie, Kaipparettu Benny A., Tsimelzon Anna, Creighton Chad J., Jiang Shiming, Polo Jose M., Melnick Ari, Meyer Rene, and Oesterreich Steffi , J Biol Chem, 2010 Feb 05, Volume 285, Issue 6, p.3608-3616, (2010)
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies., Nayar, Utthara, Lu Pin, Goldstein Rebecca L., Vider Jelena, Ballon Gianna, Rodina Anna, Taldone Tony, Erdjument-Bromage Hediye, Chomet Max, Blasberg Ronald, et al. , Blood, 2013 Oct 17, Volume 122, Issue 16, p.2837-47, (2013)