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Journal Article
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint., Swaminathan, Srividya, Huang ChuanXin, Geng Huimin, Chen Zhengshan, Harvey Richard, Kang Huining, Ng Carina, Titz Björn, Hurtz Christian, Sadiyah Mohammed Firas, et al. , Nat Med, 2013 Aug, Volume 19, Issue 8, p.1014-22, (2013)
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition., Duy, Cihangir, Hurtz Christian, Shojaee Seyedmehdi, Cerchietti Leandro, Geng Huimin, Swaminathan Srividya, Klemm Lars, Kweon Soo-Mi, Nahar Rahul, Braig Melanie, et al. , Nature, 2011 May 19, Volume 473, Issue 7347, p.384-8, (2011)
BCL6 is critical for the development of a diverse primary B cell repertoire., Duy, Cihangir, J Yu Jessica, Nahar Rahul, Swaminathan Srividya, Kweon Soo-Mi, Polo Jose M., Valls Ester, Klemm Lars, Shojaee Seyedmehdi, Cerchietti Leandro, et al. , J Exp Med, 2010 Jun 07, Volume 207, Issue 6, p.1209-21, (2010)
BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms., Parekh, Samir, Polo Jose M., Shaknovich Rita, Juszczynski Przemyslaw, Lev Paola, Ranuncolo Stella M., Yin Yingnan, Klein Ulf, Cattoretti Giorgio, Favera Riccardo Dalla, et al. , Blood, 2007 Sep 15, Volume 110, Issue 6, p.2067-74, (2007)
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia., Hurtz, Christian, Hatzi Katerina, Cerchietti Leandro, Braig Melanie, Park Eugene, Kim Yong-mi, Herzog Sebastian, Ramezani-Rad Parham, Jumaa Hassan, Müller Martin C., et al. , J Exp Med, 2011 Oct 24, Volume 208, Issue 11, p.2163-74, (2011)
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis., Hatzi, Katerina, and Melnick Ari , Trends Mol Med, 2014 Jun, Volume 20, Issue 6, p.343-52, (2014)
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling., Guryanova, Olga A., Shank Kaitlyn, Spitzer Barbara, Luciani Luisa, Koche Richard P., Garrett-Bakelman Francine E., Ganzel Chezi, Durham Benjamin H., Mohanty Abhinita, Hoermann Gregor, et al. , Nat Med, 2016 Dec, Volume 22, Issue 12, p.1488-1495, (2016)
The epichaperome is an integrated chaperome network that facilitates tumour survival., Rodina, Anna, Wang Tai, Yan Pengrong, Gomes Erica DaGama, Dunphy Mark P. S., Pillarsetty Nagavarakishore, Koren John, Gerecitano John F., Taldone Tony, Zong Hongliang, et al. , Nature, 2016 Oct 20, Volume 538, Issue 7625, p.397-401, (2016)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia., Van der Meulen, Joni, Sanghvi Viraj, Mavrakis Konstantinos, Durinck Kaat, Fang Fang, Matthijssens Filip, Rondou Pieter, Rosen Monica, Pieters Tim, Vandenberghe Peter, et al. , Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)
Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., Buchner, Maike, Park Eugene, Geng Huimin, Klemm Lars, Flach Johanna, Passegué Emmanuelle, Schjerven Hilde, Melnick Ari, Paietta Elisabeth, Kopanja Dragana, et al. , Nat Commun, 2015 Mar 10, Volume 6, p.6471, (2015)
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms., Huang, ChuanXin, Hatzi Katerina, and Melnick Ari , Nat Immunol, 2013 Apr, Volume 14, Issue 4, p.380-8, (2013)
Mechanisms of action of BCL6 during germinal center B cell development., Huang, ChuanXin, and Melnick Ari , Sci China Life Sci, 2015 Dec, Volume 58, Issue 12, p.1226-32, (2015)
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program., Park, Sun-Mi, Gönen Mithat, Vu Ly, Minuesa Gerard, Tivnan Patrick, Barlowe Trevor S., Taggart James, Lu Yuheng, Deering Raquel P., Hacohen Nir, et al. , J Clin Invest, 2015 Mar 02, Volume 125, Issue 3, p.1286-98, (2015)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival., Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al. , Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment., Will, Britta, Vogler Thomas O., Bartholdy Boris, Garrett-Bakelman Francine, Mayer Jillian, Barreyro Laura, Pandolfi Ashley, Todorova Tihomira I., Okoye-Okafor Ujunwa C., Stanley Robert F., et al. , Nat Immunol, 2013 May, Volume 14, Issue 5, p.437-45, (2013)
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo., Cerchietti, Leandro C., Ghetu Alexandru F., Zhu Xiao, Da Silva Gustavo F., Zhong Shijun, Matthews Marilyn, Bunting Karen L., Polo Jose M., Farès Christophe, Arrowsmith Cheryl H., et al. , Cancer Cell, 2010 Apr 13, Volume 17, Issue 4, p.400-11, (2010)
SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia., Ramezani-Rad, Parham, Geng Huimin, Hurtz Christian, Chan Lai N., Chen Zhengshan, Jumaa Hassan, Melnick Ari, Paietta Elisabeth, Carroll William L., Willman Cheryl L., et al. , Blood, 2013 Jan 03, Volume 121, Issue 1, p.148-55, (2013)