Found 57 results
Filters: Keyword is Epigenesis, Genetic  [Clear All Filters]
2017
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.494-505, (2017)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 08, Volume 7, Issue 8, p.868-883, (2017)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 10 12, Volume 8, Issue 1, p.877, (2017)
Genetic and epigenetic inactivation of controls mTORC1 and response to EZH2 inhibition in follicular lymphoma., Oricchio, Elisa, Katanayeva Natalya, Donaldson Maria Christine, Sungalee Stephanie, Pasion Joyce P., Béguelin Wendy, Battistello Elena, Sanghvi Viraj R., Jiang Man, Jiang Yanwen, et al. , Sci Transl Med, 2017 06 28, Volume 9, Issue 396, (2017)
2016
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia., Li, Sheng, Garrett-Bakelman Francine E., Chung Stephen S., Sanders Mathijs A., Hricik Todd, Rapaport Franck, Patel Jay, Dillon Richard, Vijay Priyanka, Brown Anna L., et al. , Nat Med, 2016 07, Volume 22, Issue 7, p.792-9, (2016)
Genetic and epigenetic heterogeneity in acute myeloid leukemia., Li, Sheng, Mason Christopher E., and Melnick Ari , Curr Opin Genet Dev, 2016 02, Volume 36, p.100-6, (2016)
A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations., Han, Dali, Lu Xingyu, Shih Alan H., Nie Ji, You Qiancheng, Xu Meng Michelle, Melnick Ari M., Levine Ross L., and He Chuan , Mol Cell, 2016 08 18, Volume 63, Issue 4, p.711-719, (2016)
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas., Bayliss, Jill, Mukherjee Piali, Lu Chao, Jain Siddhant U., Chung Chan, Martinez Daniel, Sabari Benjamin, Margol Ashley S., Panwalkar Pooja, Parolia Abhijit, et al. , Sci Transl Med, 2016 11 23, Volume 8, Issue 366, p.366ra161, (2016)
The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 07, Volume 23, Issue 4, p.377-84, (2016)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region., Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al. , Immunity, 2016 09 20, Volume 45, Issue 3, p.497-512, (2016)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., Garrett-Bakelman, Francine E., and Melnick Ari M. , Epigenomics, 2016 07, Volume 8, Issue 7, p.945-57, (2016)