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Journal Article
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis., Teater, Matt, Dominguez Pilar M., Redmond David, Chen Zhengming, Ennishi Daisuke, Scott David W., Cimmino Luisa, Ghione Paola, Chaudhuri Jayanta, Gascoyne Randy D., et al. , Nat Commun, 2018 Jan 15, Volume 9, Issue 1, p.222, (2018)
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress., Fernando, Tharu M., Marullo Rossella, Gresely Benet Pera, Phillip Jude M., Yang Shao Ning, Lundell-Smith Geoffrey, Torregroza Ingrid, Ahn Haelee, Evans Todd, Gyorffy Balazs, et al. , Cancer Discov, 2019 May, Volume 9, Issue 5, p.662-679, (2019)
BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection., Zhu, Bibo, Zhang Ruixuan, Li Chaofan, Jiang Li, Xiang Min, Ye Zhenqing, Kita Hirohito, Melnick Ari M., Dent Alexander L., and Sun Jie , Proc Natl Acad Sci U S A, 2019 Jun 11, Volume 116, Issue 24, p.11888-11893, (2019)
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia., Hurtz, Christian, Hatzi Katerina, Cerchietti Leandro, Braig Melanie, Park Eugene, Kim Yong-mi, Herzog Sebastian, Ramezani-Rad Parham, Jumaa Hassan, Müller Martin C., et al. , J Exp Med, 2011 Oct 24, Volume 208, Issue 11, p.2163-74, (2011)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia., Rampal, Raajit, Alkalin Altuna, Madzo Jozef, Vasanthakumar Aparna, Pronier Elodie, Patel Jay, Li Yushan, Ahn Jihae, Abdel-Wahab Omar, Shih Alan, et al. , Cell Rep, 2014 Dec 11, Volume 9, Issue 5, p.1841-1855, (2014)
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID., Dominguez, Pilar M., Teater Matt, Chambwe Nyasha, Kormaksson Matthias, Redmond David, Ishii Jennifer, Vuong Bao, Chaudhuri Jayanta, Melnick Ari, Vasanthakumar Aparna, et al. , Cell Rep, 2015 Sep 29, Volume 12, Issue 12, p.2086-98, (2015)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis., Pronier, Elodie, Bowman Robert L., Ahn Jihae, Glass Jacob, Kandoth Cyriac, Merlinsky Tiffany R., Whitfield Justin T., Durham Benjamin H., Gruet Antoine, Somasundara Amritha Varshini H., et al. , Blood, 2018 Sep 20, Volume 132, Issue 12, p.1265-1278, (2018)
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis., Murphy, Mark W., Sarver Aaron L., Rice Daren, Hatzi Katerina, Ye Kenny, Melnick Ari, Heckert Leslie L., Zarkower David, and Bardwell Vivian J. , Proc Natl Acad Sci U S A, 2010 Jul 27, Volume 107, Issue 30, p.13360-5, (2010)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis., Hatzi, Katerina, Geng Huimin, Doane Ashley S., Meydan Cem, LaRiviere Reed, Cardenas Mariano, Duy Cihangir, Shen Hao, Vidal Maria Nieves Cal, Baslan Timour, et al. , Nat Immunol, 2019 Jan, Volume 20, Issue 1, p.86-96, (2019)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 Jun 14, Volume 7, p.11889, (2016)
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms., Huang, ChuanXin, Hatzi Katerina, and Melnick Ari , Nat Immunol, 2013 Apr, Volume 14, Issue 4, p.380-8, (2013)
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., Li, Meng, Chiang Ying-Ling, Lyssiotis Costas A., Teater Matthew R., Hong Jun Young, Shen Hao, Wang Ling, Hu Jing, Jing Hui, Chen Zhengming, et al. , Cancer Cell, 2019 Jun 10, Volume 35, Issue 6, p.916-931.e9, (2019)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC., Nahar, Rahul, Ramezani-Rad Parham, Mossner Maximilian, Duy Cihangir, Cerchietti Leandro, Geng Huimin, Dovat Sinisa, Jumaa Hassan, B Ye Hilda, Melnick Ari, et al. , Blood, 2011 Oct 13, Volume 118, Issue 15, p.4174-8, (2011)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival., Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al. , Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment., Will, Britta, Vogler Thomas O., Bartholdy Boris, Garrett-Bakelman Francine, Mayer Jillian, Barreyro Laura, Pandolfi Ashley, Todorova Tihomira I., Okoye-Okafor Ujunwa C., Stanley Robert F., et al. , Nat Immunol, 2013 May, Volume 14, Issue 5, p.437-45, (2013)
Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease., Paz, Katelyn, Flynn Ryan, Du Jing, Qi Jun, Luznik Leo, Maillard Ivan, MacDonald Kelli P., Hill Geoffrey R., Serody Jonathan S., Murphy William J., et al. , Blood, 2019 Jan 03, Volume 133, Issue 1, p.94-99, (2019)
Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation., Rivas, Martín A., Meydan Cem, Chin Christopher R., Challman Matt F., Kim Daleum, Bhinder Bhavneet, Kloetgen Andreas, Viny Aaron D., Teater Matt R., McNally Dylan R., et al. , Nat Immunol, 2021 Feb, Volume 22, Issue 2, p.240-253, (2021)
TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate., Venturutti, Leandro, Teater Matt, Zhai Andrew, Chadburn Amy, Babiker Leena, Kim Daleum, Béguelin Wendy, Lee Tak C., Kim Youngjun, Chin Christopher R., et al. , Cell, 2020 Jul 23, Volume 182, Issue 2, p.297-316.e27, (2020)
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis., Dominguez, Pilar M., Ghamlouch Hussein, Rosikiewicz Wojciech, Kumar Parveen, Béguelin Wendy, Fontan Lorena, Rivas Martín A., Pawlikowska Patrycja, Armand Marine, Mouly Enguerran, et al. , Cancer Discov, 2018 Dec, Volume 8, Issue 12, p.1632-1653, (2018)
Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage., Chu, Chi-Shuen, Hellmuth Johannes C., Singh Rajat, Ying Hsia-Yuan, Skrabanek Lucy, Teater Matthew R., Doane Ashley S., Elemento Olivier, Melnick Ari M., and Roeder Robert G. , Mol Cell, 2020 Dec 03, Volume 80, Issue 5, p.845-861.e10, (2020)