Found 19 results
Filters: Keyword is Gene Expression Regulation  [Clear All Filters]
Journal Article
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein., Melnick, A, Carlile G W., McConnell M J., Polinger A, Hiebert S W., and Licht J D. , Blood, 2000 Dec 01, Volume 96, Issue 12, p.3939-47, (2000)
BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt., Juszczynski, Przemyslaw, Chen Linfeng, O'Donnell Evan, Polo Jose M., Ranuncolo Stella M., Dalla-Favera Riccardo, Melnick Ari, and Shipp Margaret A. , Blood, 2009 Dec 17, Volume 114, Issue 26, p.5315-21, (2009)
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis., Barish, Grant D., Yu Ruth T., Karunasiri Malith S., Becerra Diana, Kim Jason, Tseng Tiffany W., Tai Li-Jung, Leblanc Matthias, Diehl Cody, Cerchietti Leandro, et al. , Cell Metab, 2012 Apr 04, Volume 15, Issue 4, p.554-62, (2012)
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis., Hatzi, Katerina, and Melnick Ari , Trends Mol Med, 2014 Jun, Volume 20, Issue 6, p.343-52, (2014)
CtBP is an essential corepressor for BCL6 autoregulation., Mendez, Lourdes M., Polo Jose M., J Yu Jessica, Krupski Melissa, B Ding Belinda, Melnick Ari, and B Ye Hilda , Mol Cell Biol, 2008 Apr, Volume 28, Issue 7, p.2175-86, (2008)
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation., Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al. , Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)
DNMT1-interacting RNAs block gene-specific DNA methylation., Di Ruscio, Annalisa, Ebralidze Alexander K., Benoukraf Touati, Amabile Giovanni, Goff Loyal A., Terragni Jolyon, Figueroa Maria Eugenia, Pontes Lorena Lobo De Fi, Alberich-Jorda Meritxell, Zhang Pu, et al. , Nature, 2013 Nov 21, Volume 503, Issue 7476, p.371-6, (2013)
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia., Meyer, Sara E., Qin Tingting, Muench David E., Masuda Kohei, Venkatasubramanian Meenakshi, Orr Emily, Suarez Lauren, Gore Steven D., Delwel Ruud, Paietta Elisabeth, et al. , Cancer Discov, 2016 May, Volume 6, Issue 5, p.501-15, (2016)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT., Takahashi, Shinichiro, McConnell Melanie J., Harigae Hideo, Kaku Mitsuo, Sasaki Takeshi, Melnick Ari M., and Licht Jonathan D. , Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
An integrative genomic and epigenomic approach for the study of transcriptional regulation., Figueroa, Maria E., Reimers Mark, Thompson Reid F., Ye Kenny, Li Yushan, Selzer Rebecca R., Fridriksson Jakob, Paietta Elisabeth, Wiernik Peter, Green Roland D., et al. , PLoS One, 2008 Mar 26, Volume 3, Issue 3, p.e1882, (2008)
Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response., Agirre, Xabier, Meydan Cem, Jiang Yanwen, Garate Leire, Doane Ashley S., Li Zhuoning, Verma Akanksha, Paiva Bruno, Martín-Subero José I., Elemento Olivier, et al. , Nat Commun, 2019 Feb 18, Volume 10, Issue 1, p.821, (2019)
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain., K Ahmad, Farid, Melnick Ari, Lax Stuart, Bouchard Denis, Liu Jun, Kiang Chih-Li, Mayer Sebastian, Takahashi Shinichiro, Licht Jonathan D., and Prive Gilbert G. , Mol Cell, 2003 Dec, Volume 12, Issue 6, p.1551-64, (2003)
Mechanisms of action of BCL6 during germinal center B cell development., Huang, ChuanXin, and Melnick Ari , Sci China Life Sci, 2015 Dec, Volume 58, Issue 12, p.1226-32, (2015)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF., Hoatlin, M E., Zhi Y, Ball H, Silvey K, Melnick A, Stone S, Arai S, Hawe N, Owen G, Zelent A, et al. , Blood, 1999 Dec 01, Volume 94, Issue 11, p.3737-47, (1999)
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells., Polo, Jose M., Ci Weimin, Licht Jonathan D., and Melnick Ari , Blood, 2008 Aug 01, Volume 112, Issue 3, p.644-51, (2008)
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly., Qiao, Qi, Yang Chenghua, Zheng Chao, Fontan Lorena, David Liron, Yu Xiong, Bracken Clay, Rosen Monica, Melnick Ari, Egelman Edward H., et al. , Mol Cell, 2013 Sep 26, Volume 51, Issue 6, p.766-79, (2013)