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Found 16 results
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Melnick, Ari M
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2021
H1 histones control the epigenetic landscape by local chromatin compaction.
,
Willcockson, Michael A.
,
Healton Sean E.
,
Weiss Cary N.
,
Bartholdy Boris A.
,
Botbol Yair
,
Mishra Laxmi N.
,
Sidhwani Dhruv S.
,
Wilson Tommy J.
,
Pinto Hugo B.
,
Maron Maxim I.
, et al.
, Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
2020
Clonal Hematopoiesis Before, During, and After Human Spaceflight.
,
Mencia-Trinchant, Nuria
,
MacKay Matthew J.
,
Chin Christopher
,
Afshinnekoo Ebrahim
,
Foox Jonathan
,
Meydan Cem
,
Butler Daniel
,
Mozsary Christopher
,
Vernice Nicholas A.
,
Darby Charlotte
, et al.
, Cell Rep, 2020 Dec 08, Volume 33, Issue 10, p.108458, (2020)
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy.
,
Fabre, Marie-Sophie
,
Stanton Nicole M.
,
Slatter Tania L.
,
Lee Samuel
,
Senanayake Dinindu
,
Gordon Rosemary M. A.
,
M Castro Leticia
,
Rowe Matthew R.
,
Taha Ahmad
,
Royds Janice A.
, et al.
, PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML.
,
Li, Sheng
,
Chen Xiaowen
,
Wang Jiahui
,
Meydan Cem
,
Glass Jacob L.
,
Shih Alan H.
,
Delwel Ruud
,
Levine Ross L.
,
Mason Christopher E.
, and
Melnick Ari M.
, Cancer Discov, 2020 Dec, Volume 10, Issue 12, p.1934-1949, (2020)
2019
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress.
,
Fernando, Tharu M.
,
Marullo Rossella
,
Gresely Benet Pera
,
Phillip Jude M.
,
Yang Shao Ning
,
Lundell-Smith Geoffrey
,
Torregroza Ingrid
,
Ahn Haelee
,
Evans Todd
,
Gyorffy Balazs
, et al.
, Cancer Discov, 2019 May, Volume 9, Issue 5, p.662-679, (2019)
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization.
,
Gomes, Ana P.
,
Ilter Didem
,
Low Vivien
,
Rosenzweig Adam
,
Shen Zih-Jie
,
Schild Tanya
,
Rivas Martín A.
,
Er Ekrem E.
,
McNally Dylan R.
,
Mutvei Anders P.
, et al.
, Cancer Cell, 2019 Oct 14, Volume 36, Issue 4, p.402-417.e13, (2019)
Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells.
,
Purwada, Alberto
,
Shah Shivem B.
,
Béguelin Wendy
,
August Avery
,
Melnick Ari M.
, and
Singh Ankur
, Biomaterials, 2019 Apr, Volume 198, p.27-36, (2019)
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
,
Garrett-Bakelman, Francine E.
,
Darshi Manjula
,
Green Stefan J.
,
Gur Ruben C.
,
Lin Ling
,
Macias Brandon R.
,
McKenna Miles J.
,
Meydan Cem
,
Mishra Tejaswini
,
Nasrini Jad
, et al.
, Science, 2019 Apr 12, Volume 364, Issue 6436, (2019)
2017
CD99 is a therapeutic target on disease stem cells in myeloid malignancies.
,
Chung, Stephen S.
,
Eng William S.
,
Hu Wenhuo
,
Khalaj Mona
,
Garrett-Bakelman Francine E.
,
Tavakkoli Montreh
,
Levine Ross L.
,
Carroll Martin
,
Klimek Virginia M.
,
Melnick Ari M.
, et al.
, Sci Transl Med, 2017 Jan 25, Volume 9, Issue 374, (2017)
2016
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
,
Li, Sheng
,
Garrett-Bakelman Francine E.
,
Chung Stephen S.
,
Sanders Mathijs A.
,
Hricik Todd
,
Rapaport Franck
,
Patel Jay
,
Dillon Richard
,
Vijay Priyanka
,
Brown Anna L.
, et al.
, Nat Med, 2016 Jul, Volume 22, Issue 7, p.792-9, (2016)
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.
,
Cardenas, Mariano G.
,
Yu Wenbo
,
Béguelin Wendy
,
Teater Matthew R.
,
Geng Huimin
,
Goldstein Rebecca L.
,
Oswald Erin
,
Hatzi Katerina
,
Yang Shao-Ning
,
Cohen Joanna
, et al.
, J Clin Invest, 2016 Sep 01, Volume 126, Issue 9, p.3351-62, (2016)
2015
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.
,
Van der Meulen, Joni
,
Sanghvi Viraj
,
Mavrakis Konstantinos
,
Durinck Kaat
,
Fang Fang
,
Matthijssens Filip
,
Rondou Pieter
,
Rosen Monica
,
Pieters Tim
,
Vandenberghe Peter
, et al.
, Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)
VII. Are lymphomas driven by epigenetic lesions?
,
Boss, Isaac W.
, and
Melnick Ari M.
, Hematol Oncol, 2015 Jun, Volume 33 Suppl 1, p.42-5, (2015)
2013
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
,
Lin, Pei-Chun
,
Chiu Ya-Lin
,
Banerjee Samprit
,
Park Kyung
,
Mosquera Juan Miguel
,
Giannopoulou Eugenia
,
Alves Pedro
,
Tewari Ashutosh K.
,
Gerstein Mark B.
,
Beltran Himisha
, et al.
, Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1232-44, (2013)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.
,
Nischal, Sangeeta
,
Bhattacharyya Sanchari
,
Christopeit Maximilian
,
Yu Yiting
,
Zhou Li
,
Bhagat Tushar D.
,
Sohal Davendra
,
Will Britta
,
Mo Yongkai
,
Suzuki Masako
, et al.
, Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
2012
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis.
,
Barish, Grant D.
,
Yu Ruth T.
,
Karunasiri Malith S.
,
Becerra Diana
,
Kim Jason
,
Tseng Tiffany W.
,
Tai Li-Jung
,
Leblanc Matthias
,
Diehl Cody
,
Cerchietti Leandro
, et al.
, Cell Metab, 2012 Apr 04, Volume 15, Issue 4, p.554-62, (2012)