Found 72 results
Filters: Keyword is DNA-Binding Proteins  [Clear All Filters]
2015
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms., Hatzi, Katerina, J Nance Philip, Kroenke Mark A., Bothwell Marcella, Haddad Elias K., Melnick Ari, and Crotty Shane , J Exp Med, 2015 Apr 06, Volume 212, Issue 4, p.539-53, (2015)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)
Mechanisms of action of BCL6 during germinal center B cell development., Huang, ChuanXin, and Melnick Ari , Sci China Life Sci, 2015 Dec, Volume 58, Issue 12, p.1226-32, (2015)
Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia., Geng, Huimin, Hurtz Christian, Lenz Kyle B., Chen Zhengshan, Baumjohann Dirk, Thompson Sarah, Goloviznina Natalya A., Chen Wei-Yi, Huan Jianya, LaTocha Dorian, et al. , Cancer Cell, 2015 Mar 09, Volume 27, Issue 3, p.409-25, (2015)
2014
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers., Huang, ChuanXin, Gonzalez David G., Cote Christine M., Jiang Yanwen, Hatzi Katerina, Teater Matt, Dai Kezhi, Hla Timothy, Haberman Ann M., and Melnick Ari , Cell Rep, 2014 Sep 11, Volume 8, Issue 5, p.1497-508, (2014)
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis., Hatzi, Katerina, and Melnick Ari , Trends Mol Med, 2014 Jun, Volume 20, Issue 6, p.343-52, (2014)
Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation., Huang, ChuanXin, Geng Huimin, Boss Isaac, Wang Ling, and Melnick Ari , Blood, 2014 Feb 13, Volume 123, Issue 7, p.1012-20, (2014)
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas., Jiang, Yanwen, Redmond David, Nie Kui, Eng Ken W., Clozel Thomas, Martin Peter, Tan Leonard Hc, Melnick Ari M., Tam Wayne, and Elemento Olivier , Genome Biol, 2014 Aug 15, Volume 15, Issue 8, p.432, (2014)
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia., Rampal, Raajit, Alkalin Altuna, Madzo Jozef, Vasanthakumar Aparna, Pronier Elodie, Patel Jay, Li Yushan, Ahn Jihae, Abdel-Wahab Omar, Shih Alan, et al. , Cell Rep, 2014 Dec 11, Volume 9, Issue 5, p.1841-1855, (2014)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma., Green, Michael R., Vicente-Dueñas Carolina, Romero-Camarero Isabel, Liu Chih Long, Dai Bo, González-Herrero Inés, García-Ramírez Idoia, Alonso-Escudero Esther, Iqbal Javeed, Chan Wing C., et al. , Nat Commun, 2014 Jun 02, Volume 5, p.3904, (2014)