Found 7 results
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Journal Article
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis., Pronier, Elodie, Bowman Robert L., Ahn Jihae, Glass Jacob, Kandoth Cyriac, Merlinsky Tiffany R., Whitfield Justin T., Durham Benjamin H., Gruet Antoine, Somasundara Amritha Varshini H., et al. , Blood, 2018 Sep 20, Volume 132, Issue 12, p.1265-1278, (2018)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Sasaki, Masato, Knobbe Christiane B., Munger Joshua C., Lind Evan F., Brenner Dirk, Brüstle Anne, Harris Isaac S., Holmes Roxanne, Wakeham Andrew, Haight Jillian, et al. , Nature, 2012 Aug 30, Volume 488, Issue 7413, p.656-9, (2012)
is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Moran-Crusio, Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, et al. , Cancer Cell, 2011 Jul 12, Volume 20, Issue 1, p.11-24, (2011)