Found 23 results
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Journal Article
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein., Melnick, A, Carlile G W., McConnell M J., Polinger A, Hiebert S W., and Licht J D. , Blood, 2000 Dec 01, Volume 96, Issue 12, p.3939-47, (2000)
BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms., Parekh, Samir, Polo Jose M., Shaknovich Rita, Juszczynski Przemyslaw, Lev Paola, Ranuncolo Stella M., Yin Yingnan, Klein Ulf, Cattoretti Giorgio, Favera Riccardo Dalla, et al. , Blood, 2007 Sep 15, Volume 110, Issue 6, p.2067-74, (2007)
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900., Gönen, Mithat, Sun Zhuoxin, Figueroa Maria E., Patel Jay P., Abdel-Wahab Omar, Racevskis Janis, Ketterling Rhett P., Fernandez Hugo, Rowe Jacob M., Tallman Martin S., et al. , Blood, 2012 Sep 13, Volume 120, Issue 11, p.2297-306, (2012)
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas., Culjkovic-Kraljacic, Biljana, Fernando Tharu M., Marullo Rossella, Calvo-Vidal Nieves, Verma Akanksha, Yang ShaoNing, Tabbò Fabrizio, Gaudiano Marcello, Zahreddine Hiba, Goldstein Rebecca L., et al. , Blood, 2016 Feb 18, Volume 127, Issue 7, p.858-68, (2016)
CtBP is an essential corepressor for BCL6 autoregulation., Mendez, Lourdes M., Polo Jose M., J Yu Jessica, Krupski Melissa, B Ding Belinda, Melnick Ari, and B Ye Hilda , Mol Cell Biol, 2008 Apr, Volume 28, Issue 7, p.2175-86, (2008)
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia., Melnick, A, and Licht J D. , Blood, 1999 May 15, Volume 93, Issue 10, p.3167-215, (1999)
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas., Jiang, Yanwen, Redmond David, Nie Kui, Eng Ken W., Clozel Thomas, Martin Peter, Tan Leonard Hc, Melnick Ari M., Tam Wayne, and Elemento Olivier , Genome Biol, 2014 Aug 15, Volume 15, Issue 8, p.432, (2014)
Epigenomic evolution in diffuse large B-cell lymphomas., Pan, Heng, Jiang Yanwen, Boi Michela, Tabbò Fabrizio, Redmond David, Nie Kui, Ladetto Marco, Chiappella Annalisa, Cerchietti Leandro, Shaknovich Rita, et al. , Nat Commun, 2015 Apr 20, Volume 6, p.6921, (2015)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models., Caldas-Lopes, Eloisi, Cerchietti Leandro, Ahn James H., Clement Cristina C., Robles Ana I., Rodina Anna, Moulick Kamalika, Taldone Tony, Gozman Alexander, Guo Yunke, et al. , Proc Natl Acad Sci U S A, 2009 May 19, Volume 106, Issue 20, p.8368-73, (2009)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
Molecular pathways: targeting MALT1 paracaspase activity in lymphoma., Fontan, Lorena, and Melnick Ari , Clin Cancer Res, 2013 Dec 15, Volume 19, Issue 24, p.6662-8, (2013)
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia., Ribeiro, Ana Flávia Ti, Pratcorona Marta, Erpelinck-Verschueren Claudia, Rockova Veronika, Sanders Mathijs, Abbas Saman, Figueroa Maria E., Zeilemaker Annelieke, Melnick Ari, Löwenberg Bob, et al. , Blood, 2012 Jun 14, Volume 119, Issue 24, p.5824-31, (2012)
SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia., Ramezani-Rad, Parham, Geng Huimin, Hurtz Christian, Chan Lai N., Chen Zhengshan, Jumaa Hassan, Melnick Ari, Paietta Elisabeth, Carroll William L., Willman Cheryl L., et al. , Blood, 2013 Jan 03, Volume 121, Issue 1, p.148-55, (2013)
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth., Fontan, Lorena, Qiao Qi, Hatcher John M., Casalena Gabriella, Us Ilkay, Teater Matt, Durant Matt, Du Guangyan, Xia Min, Bilchuk Natalia, et al. , J Clin Invest, 2018 Oct 01, Volume 128, Issue 10, p.4397-4412, (2018)
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly., Qiao, Qi, Yang Chenghua, Zheng Chao, Fontan Lorena, David Liron, Yu Xiong, Bracken Clay, Rosen Monica, Melnick Ari, Egelman Edward H., et al. , Mol Cell, 2013 Sep 26, Volume 51, Issue 6, p.766-79, (2013)
SYK inhibition and response prediction in diffuse large B-cell lymphoma., Cheng, Shuhua, Coffey Greg, X Zhang Hannah, Shaknovich Rita, Song Zibo, Lu Pin, Pandey Anjali, Melnick Ari M., Sinha Uma, and Y Wang Lynn , Blood, 2011 Dec 08, Volume 118, Issue 24, p.6342-52, (2011)
Targeting lymphomas through MALT1 inhibition., Fontan, Lorena, and Melnick Ari , Oncotarget, 2012 Dec, Volume 3, Issue 12, p.1493-4, (2012)
Translocations of the RARalpha gene in acute promyelocytic leukemia., Zelent, A, Guidez F, Melnick A, Waxman S, and Licht J D. , Oncogene, 2001 Oct 29, Volume 20, Issue 49, p.7186-203, (2001)
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes., Chambwe, Nyasha, Kormaksson Matthias, Geng Huimin, De Subhajyoti, Michor Franziska, Johnson Nathalie A., Morin Ryan D., Scott David W., Godley Lucy A., Gascoyne Randy D., et al. , Blood, 2014 Mar 13, Volume 123, Issue 11, p.1699-708, (2014)
VII. Are lymphomas driven by epigenetic lesions?, Boss, Isaac W., and Melnick Ari M. , Hematol Oncol, 2015 Jun, Volume 33 Suppl 1, p.42-5, (2015)