Found 86 results
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Journal Article
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes., Bunting, Karen L., and Melnick Ari M. , Curr Opin Immunol, 2013 Jun, Volume 25, Issue 3, p.339-46, (2013)
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling., Park-Min, Kyung-Hyun, Lee Eun Young, Moskowitz Neal K., Lim Elisha, Lee Sun-Kyeong, Lorenzo Joseph A., Huang ChuanXin, Melnick Ari M., P Purdue Edward, Goldring Steven R., et al. , J Bone Miner Res, 2013 Jan, Volume 28, Issue 1, p.135-49, (2013)
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., Garrett-Bakelman, Francine E., Darshi Manjula, Green Stefan J., Gur Ruben C., Lin Ling, Macias Brandon R., McKenna Miles J., Meydan Cem, Mishra Tejaswini, Nasrini Jad, et al. , Science, 2019 Apr 12, Volume 364, Issue 6436, (2019)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., Garrett-Bakelman, Francine E., and Melnick Ari M. , Epigenomics, 2016 Jul, Volume 8, Issue 7, p.945-57, (2016)
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., Béguelin, Wendy, Teater Matt, Meydan Cem, Hoehn Kenneth B., Phillip Jude M., Soshnev Alexey A., Venturutti Leandro, Rivas Martín A., Calvo-Fernández María T., Gutierrez Johana, et al. , Cancer Cell, 2020 May 11, Volume 37, Issue 5, p.655-673.e11, (2020)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region., Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al. , Immunity, 2016 Sep 20, Volume 45, Issue 3, p.497-512, (2016)
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., Lu, Xiangdong, Chu Chi-Shuen, Fang Terry, Rayon-Estrada Violeta, Fang Fang, Patke Alina, Qian Ye, Clarke Stephen H., Melnick Ari M., Zhang Yi, et al. , Cell Rep, 2019 Jul 09, Volume 28, Issue 2, p.472-485.e5, (2019)
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition., Ennishi, Daisuke, Takata Katsuyoshi, Béguelin Wendy, Duns Gerben, Mottok Anja, Farinha Pedro, Bashashati Ali, Saberi Saeed, Boyle Merrill, Meissner Barbara, et al. , Cancer Discov, 2019 Apr, Volume 9, Issue 4, p.546-563, (2019)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms., Nischal, Sangeeta, Bhattacharyya Sanchari, Christopeit Maximilian, Yu Yiting, Zhou Li, Bhagat Tushar D., Sohal Davendra, Will Britta, Mo Yongkai, Suzuki Masako, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 Jul, Volume 23, Issue 4, p.377-84, (2016)
Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Tian, Ye F., Ahn Haelee, Schneider Rebecca S., Yang Shao Ning, Roman-Gonzalez Lidia, Melnick Ari M., Cerchietti Leandro, and Singh Ankur , Biomaterials, 2015 Dec, Volume 73, p.110-9, (2015)
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia., Geng, Huimin, Brennan Sarah, Milne Thomas A., Chen Wei-Yi, Li Yushan, Hurtz Christian, Kweon Soo-Mi, Zickl Lynette, Shojaee Seyedmehdi, Neuberg Donna, et al. , Cancer Discov, 2012 Nov, Volume 2, Issue 11, p.1004-23, (2012)
The Impact of Heterogeneity on Single-Cell Sequencing., Goldman, Samantha L., MacKay Matthew, Afshinnekoo Ebrahim, Melnick Ari M., Wu Shuxiu, and Mason Christopher E. , Front Genet, 2019, Volume 10, p.8, (2019)
How Biophysical Forces Regulate Human B Cell Lymphomas., Apoorva, F, Loiben Alexander M., Shah Shivem B., Purwada Alberto, Fontan Lorena, Goldstein Rebecca, Kirby Brian J., Melnick Ari M., Cosgrove Benjamin D., and Singh Ankur , Cell Rep, 2018 Apr 10, Volume 23, Issue 2, p.499-511, (2018)
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 Jun 14, Volume 7, p.11889, (2016)
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture., Yusufova, Nevin, Kloetgen Andreas, Teater Matt, Osunsade Adewola, Camarillo Jeannie M., Chin Christopher R., Doane Ashley S., Venters Bryan J., Portillo-Ledesma Stephanie, Conway Joseph, et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.299-305, (2021)
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis., Hatzi, Katerina, Geng Huimin, Doane Ashley S., Meydan Cem, LaRiviere Reed, Cardenas Mariano, Duy Cihangir, Shen Hao, Vidal Maria Nieves Cal, Baslan Timour, et al. , Nat Immunol, 2019 Jan, Volume 20, Issue 1, p.86-96, (2019)
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells., Ha, Kyungsoo, Fiskus Warren, Choi Dong Soon, Bhaskara Srividya, Cerchietti Leandro, Devaraj Santhana G. T., Shah Bhavin, Sharma Sunil, Chang Jenny C., Melnick Ari M., et al. , Oncotarget, 2014 Jul 30, Volume 5, Issue 14, p.5637-50, (2014)
A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations., Han, Dali, Lu Xingyu, Shih Alan H., Nie Ji, You Qiancheng, Xu Meng Michelle, Melnick Ari M., Levine Ross L., and He Chuan , Mol Cell, 2016 Aug 18, Volume 63, Issue 4, p.711-719, (2016)
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia., Chung, Stephen S., Kim Eunhee, Park Jae H., Chung Young Rock, Lito Piro, Teruya-Feldstein Julie, Hu Wenhuo, Béguelin Wendy, Monette Sebastien, Duy Cihangir, et al. , Sci Transl Med, 2014 May 28, Volume 6, Issue 238, p.238ra71, (2014)
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia., Van der Meulen, Joni, Sanghvi Viraj, Mavrakis Konstantinos, Durinck Kaat, Fang Fang, Matthijssens Filip, Rondou Pieter, Rosen Monica, Pieters Tim, Vandenberghe Peter, et al. , Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., Jiang, Yanwen, T Soong David, Wang Ling, Melnick Ari M., and Elemento Olivier , PLoS One, 2012, Volume 7, Issue 7, p.e40332, (2012)