Found 67 results
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Journal Article
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters., Hatzi, Katerina, Jiang Yanwen, Huang ChuanXin, Garrett-Bakelman Francine, Gearhart Micah D., Giannopoulou Eugenia G., Zumbo Paul, Kirouac Kevin, Bhaskara Srividya, Polo Jose M., et al. , Cell Rep, 2013 Aug 15, Volume 4, Issue 3, p.578-88, (2013)
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma., Cubedo, Elena, Gentles Andrew J., Huang ChuanXin, Natkunam Yasodha, Bhatt Shruti, Lu Xiaoqing, Jiang Xiaoyu, Romero-Camarero Isabel, Freud Aharon, Zhao Shuchun, et al. , Blood, 2012 Jun 07, Volume 119, Issue 23, p.5478-91, (2012)
Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design., Cheng, Huimin, Linhares Brian M., Yu Wenbo, Cardenas Mariano G., Ai Yong, Jiang Wenjuan, Winkler Alyssa, Cohen Sandra, Melnick Ari, MacKerell Alexander, et al. , J Med Chem, 2018 Sep 13, Volume 61, Issue 17, p.7573-7588, (2018)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas., Cerchietti, Leandro, Damm-Welk Christine, Vater Inga, Klapper Wolfram, Harder Lana, Pott Christiane, Yang Shao Ning, Reiter Alfred, Siebert Reiner, Melnick Ari, et al. , PLoS One, 2011 Apr 08, Volume 6, Issue 4, p.e18436, (2011)
An integrative genomic and epigenomic approach for the study of transcriptional regulation., Figueroa, Maria E., Reimers Mark, Thompson Reid F., Ye Kenny, Li Yushan, Selzer Rebecca R., Fridriksson Jakob, Paietta Elisabeth, Wiernik Peter, Green Roland D., et al. , PLoS One, 2008 Mar 26, Volume 3, Issue 3, p.e1882, (2008)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation., Wang, Lan, Gural Alexander, Sun Xiao-Jian, Zhao Xinyang, Perna Fabiana, Huang Gang, Hatlen Megan A., Vu Ly, Liu Fan, Xu Haiming, et al. , Science, 2011 Aug 05, Volume 333, Issue 6043, p.765-9, (2011)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
Loss of BAP1 function leads to EZH2-dependent transformation., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2015 Nov, Volume 21, Issue 11, p.1344-9, (2015)
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 12 15, Volume 77, Issue 24, p.7038-7048, (2017)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma., Clozel, Thomas, Yang ShaoNing, Elstrom Rebecca L., Tam Wayne, Martin Peter, Kormaksson Matthias, Banerjee Samprit, Vasanthakumar Aparna, Culjkovic Biljana, Scott David W., et al. , Cancer Discov, 2013 Sep, Volume 3, Issue 9, p.1002-19, (2013)
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles., Akalin, Altuna, Kormaksson Matthias, Li Sheng, Garrett-Bakelman Francine E., Figueroa Maria E., Melnick Ari, and Mason Christopher E. , Genome Biol, 2012 Oct 03, Volume 13, Issue 10, p.R87, (2012)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms., Nischal, Sangeeta, Bhattacharyya Sanchari, Christopeit Maximilian, Yu Yiting, Zhou Li, Bhagat Tushar D., Sohal Davendra, Will Britta, Mo Yongkai, Suzuki Masako, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis., Kozloski, Goldi A., Jiang Xiaoyu, Bhatt Shruti, Ruiz Jose, Vega Francisco, Shaknovich Rita, Melnick Ari, and Lossos Izidore S. , Blood, 2016 06 09, Volume 127, Issue 23, p.2856-66, (2016)
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition., Ennishi, Daisuke, Takata Katsuyoshi, Béguelin Wendy, Duns Gerben, Mottok Anja, Farinha Pedro, Bashashati Ali, Saberi Saeed, Boyle Merrill, Meissner Barbara, et al. , Cancer Discov, 2019 Apr, Volume 9, Issue 4, p.546-563, (2019)
Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program., Park, Sun-Mi, Gönen Mithat, Vu Ly, Minuesa Gerard, Tivnan Patrick, Barlowe Trevor S., Taggart James, Lu Yuheng, Deering Raquel P., Hacohen Nir, et al. , J Clin Invest, 2015 Mar 02, Volume 125, Issue 3, p.1286-98, (2015)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., Fabre, Marie-Sophie, Stanton Nicole M., Slatter Tania L., Lee Samuel, Senanayake Dinindu, Gordon Rosemary M. A., M Castro Leticia, Rowe Matthew R., Taha Ahmad, Royds Janice A., et al. , PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)
ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia., Maes, Tamara, Mascaró Cristina, Tirapu Iñigo, Estiarte Angels, Ciceri Filippo, Lunardi Serena, Guibourt Nathalie, Perdones Alvaro, Lufino Michele M. P., Somervaille Tim C. P., et al. , Cancer Cell, 2018 Mar 12, Volume 33, Issue 3, p.495-511.e12, (2018)
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo., Cerchietti, Leandro C., Yang Shao Ning, Shaknovich Rita, Hatzi Katerina, Polo Jose M., Chadburn Amy, Dowdy Steven F., and Melnick Ari , Blood, 2009 Apr 09, Volume 113, Issue 15, p.3397-405, (2009)
Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al. , J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex., Vu, Ly P., Perna Fabiana, Wang Lan, Voza Francesca, Figueroa Maria E., Tempst Paul, Erdjument-Bromage Hediye, Gao Rui, Chen Sisi, Paietta Elisabeth, et al. , Cell Rep, 2013 Dec 26, Volume 5, Issue 6, p.1625-38, (2013)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival., Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al. , Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)