Found 271 results
2008
B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma., Ci, Weimin, Polo Jose M., and Melnick Ari , Curr Opin Hematol, 2008 Jul, Volume 15, Issue 4, p.381-90, (2008)
BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells., Ranuncolo, Stella M., Polo Jose M., and Melnick Ari , Blood Cells Mol Dis, 2008 Jul-Aug, Volume 41, Issue 1, p.95-9, (2008)
BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner., Ranuncolo, Stella Maris, Wang Ling, Polo Jose M., Dell'Oso Tania, Dierov Jamil, Gaymes Terry J., Rassool Feyruz, Carroll Martin, and Melnick Ari , J Biol Chem, 2008 Aug 15, Volume 283, Issue 33, p.22565-72, (2008)
CtBP is an essential corepressor for BCL6 autoregulation., Mendez, Lourdes M., Polo Jose M., J Yu Jessica, Krupski Melissa, B Ding Belinda, Melnick Ari, and B Ye Hilda , Mol Cell Biol, 2008 Apr, Volume 28, Issue 7, p.2175-86, (2008)
Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics., Zelent, Arthur, Petrie Kevin, Boix-Chornet Manuel, Melnick Ari M., Waxman Samuel, and Gore Steven D. , Cancer Res, 2008 Jul 01, Volume 68, Issue 13, p.4967-70, (2008)
HDAC4 promotes growth of colon cancer cells via repression of p21., Wilson, Andrew J., Byun Do-Sun, Nasser Shannon, Murray Lucas B., Ayyanar Kanyalakshmi, Arango Diego, Figueroa Maria, Melnick Ari, Kao Gary D., Augenlicht Leonard H., et al. , Mol Biol Cell, 2008 Oct, Volume 19, Issue 10, p.4062-75, (2008)
An integrative genomic and epigenomic approach for the study of transcriptional regulation., Figueroa, Maria E., Reimers Mark, Thompson Reid F., Ye Kenny, Li Yushan, Selzer Rebecca R., Fridriksson Jakob, Paietta Elisabeth, Wiernik Peter, Green Roland D., et al. , PLoS One, 2008 Mar 26, Volume 3, Issue 3, p.e1882, (2008)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration., Sohal, Davendra, Yeatts Andrew, Ye Kenny, Pellagatti Andrea, Zhou Li, Pahanish Perry, Mo Yongkai, Bhagat Tushar, Mariadason John, Boultwood Jacqueline, et al. , PLoS One, 2008 Aug 13, Volume 3, Issue 8, p.e2965, (2008)
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells., Polo, Jose M., Ci Weimin, Licht Jonathan D., and Melnick Ari , Blood, 2008 Aug 01, Volume 112, Issue 3, p.644-51, (2008)
Sequential transcription factor targeting for diffuse large B-cell lymphomas., Cerchietti, Leandro C., Polo Jose M., Da Silva Gustavo F., Farinha Pedro, Shaknovich Rita, Gascoyne Randy D., Dowdy Steven F., and Melnick Ari , Cancer Res, 2008 May 01, Volume 68, Issue 9, p.3361-9, (2008)
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer., Ghetu, Alexandru F., Corcoran Connie M., Cerchietti Leandro, Bardwell Vivian J., Melnick Ari, and Prive Gilbert G. , Mol Cell, 2008 Feb 15, Volume 29, Issue 3, p.384-91, (2008)
Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas., Parekh, Samir, Privé Gilbert, and Melnick Ari , Leuk Lymphoma, 2008 May, Volume 49, Issue 5, p.874-82, (2008)
Transitioning from fellowship to a physician-scientist career track., Melnick, Ari , Hematology Am Soc Hematol Educ Program, 2008, p.16-22, (2008)
2009
BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt., Juszczynski, Przemyslaw, Chen Linfeng, O'Donnell Evan, Polo Jose M., Ranuncolo Stella M., Dalla-Favera Riccardo, Melnick Ari, and Shipp Margaret A. , Blood, 2009 Dec 17, Volume 114, Issue 26, p.5315-21, (2009)
The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL., Ci, Weimin, Polo Jose M., Cerchietti Leandro, Shaknovich Rita, Wang Ling, Yang Shao Ning, Ye Kenny, Farinha Pedro, Horsman Douglas E., Gascoyne Randy D., et al. , Blood, 2009 May 28, Volume 113, Issue 22, p.5536-48, (2009)
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias., Figueroa, Maria E., Melnick Ari, and Greally John M. , Methods Mol Biol, 2009, Volume 538, p.395-407, (2009)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers., Oda, Mayumi, Glass Jacob L., Thompson Reid F., Mo Yongkai, Olivier Emmanuel N., Figueroa Maria E., Selzer Rebecca R., Richmond Todd A., Zhang Xinmin, Dannenberg Luke, et al. , Nucleic Acids Res, 2009 Jul, Volume 37, Issue 12, p.3829-39, (2009)
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models., Caldas-Lopes, Eloisi, Cerchietti Leandro, Ahn James H., Clement Cristina C., Robles Ana I., Rodina Anna, Moulick Kamalika, Taldone Tony, Gozman Alexander, Guo Yunke, et al. , Proc Natl Acad Sci U S A, 2009 May 19, Volume 106, Issue 20, p.8368-73, (2009)
Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells., Laurenzana, Anna, Petruccelli Luca A., Pettersson Filippa, Figueroa Maria Eugenia, Melnick Ari, Baldwin Albert S., Paoletti Francesco, and Miller Wilson H. , Cancer Res, 2009 Jan 01, Volume 69, Issue 1, p.55-64, (2009)
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation., Figueroa, Maria E., Skrabanek Lucy, Li Yushan, Jiemjit Anchalee, Fandy Tamer E., Paietta Elisabeth, Fernandez Hugo, Tallman Martin S., Greally John M., Carraway Hetty, et al. , Blood, 2009 Oct 15, Volume 114, Issue 16, p.3448-58, (2009)
Outcome of deferred initial therapy in mantle-cell lymphoma., Martin, Peter, Chadburn Amy, Christos Paul, Weil Karen, Furman Richard R., Ruan Jia, Elstrom Rebecca, Niesvizky Ruben, Ely Scott, Diliberto Maurizio, et al. , J Clin Oncol, 2009 Mar 10, Volume 27, Issue 8, p.1209-13, (2009)