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Found 271 results
Author
Title
Type
Year
2006
Specific peptides for the therapeutic targeting of oncogenes.
,
Prive, Gilbert G.
, and
Melnick Ari
, Curr Opin Genet Dev, 2006 Feb, Volume 16, Issue 1, p.71-7, (2006)
2005
Reprogramming specific gene expression pathways in B-cell lymphomas.
,
Melnick, Ari
, Cell Cycle, 2005 Feb, Volume 4, Issue 2, p.239-41, (2005)
The theoretical basis of transcriptional therapy of cancer: can it be put into practice?
,
Melnick, Ari M.
,
Adelson Kerin
, and
Licht Jonathan D.
, J Clin Oncol, 2005 Jun 10, Volume 23, Issue 17, p.3957-70, (2005)
2004
ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein.
,
Chevallier, Nathalie
,
Corcoran Connie M.
,
Lennon Christine
,
Hyjek Elizabeth
,
Chadburn Amy
,
Bardwell Vivian J.
,
Licht Jonathan D.
, and
Melnick Ari
, Blood, 2004 Feb 15, Volume 103, Issue 4, p.1454-63, (2004)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT.
,
Takahashi, Shinichiro
,
McConnell Melanie J.
,
Harigae Hideo
,
Kaku Mitsuo
,
Sasaki Takeshi
,
Melnick Ari M.
, and
Licht Jonathan D.
, Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.
,
Polo, Jose M.
,
Dell'Oso Tania
,
Ranuncolo Stella Maris
,
Cerchietti Leandro
,
Beck David
,
Da Silva Gustavo F.
,
Prive Gilbert G.
,
Licht Jonathan D.
, and
Melnick Ari
, Nat Med, 2004 Dec, Volume 10, Issue 12, p.1329-35, (2004)
2003
Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
,
K Ahmad, Farid
,
Melnick Ari
,
Lax Stuart
,
Bouchard Denis
,
Liu Jun
,
Kiang Chih-Li
,
Mayer Sebastian
,
Takahashi Shinichiro
,
Licht Jonathan D.
, and
Prive Gilbert G.
, Mol Cell, 2003 Dec, Volume 12, Issue 6, p.1551-64, (2003)
Molecular pathogenesis of acute promyelocytic leukaemia and APL variants.
,
Sirulnik, Andres
,
Melnick Ari
,
Zelent Arthur
, and
Licht Jonathan D.
, Best Pract Res Clin Haematol, 2003 Sep, Volume 16, Issue 3, p.387-408, (2003)
2002
Autosomal dominant chorea-acanthocytosis with polyglutamine-containing neuronal inclusions.
,
Walker, R H.
,
Morgello S
,
Davidoff-Feldman B
,
Melnick A
,
Walsh M J.
,
Shashidharan P
, and
Brin M F.
, Neurology, 2002 Apr 09, Volume 58, Issue 7, p.1031-7, (2002)
Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.
,
Melnick, Ari
,
Carlile Graeme
,
K Ahmad Farid
,
Kiang Chih-Li
,
Corcoran Connie
,
Bardwell Vivian
,
Prive Gilbert G.
, and
Licht Jonathan D.
, Mol Cell Biol, 2002 Mar, Volume 22, Issue 6, p.1804-18, (2002)
Histone deacetylases as therapeutic targets in hematologic malignancies.
,
Melnick, Ari
, and
Licht Jonathan D.
, Curr Opin Hematol, 2002 Jul, Volume 9, Issue 4, p.322-32, (2002)
Spotlight on acute promyelocytic leukemia: controversies and challenges.
,
Melnick, A
, Leukemia, 2002 Oct, Volume 16, Issue 10, p.1893-5, (2002)
2001
Translocations of the RARalpha gene in acute promyelocytic leukemia.
,
Zelent, A
,
Guidez F
,
Melnick A
,
Waxman S
, and
Licht J D.
, Oncogene, 2001 Oct 29, Volume 20, Issue 49, p.7186-203, (2001)
2000
AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by the promyelocytic leukemia zinc finger protein.
,
Melnick, A
,
Carlile G W.
,
McConnell M J.
,
Polinger A
,
Hiebert S W.
, and
Licht J D.
, Blood, 2000 Dec 01, Volume 96, Issue 12, p.3939-47, (2000)
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein.
,
Melnick, A M.
,
Westendorf J J.
,
Polinger A
,
Carlile G W.
,
Arai S
,
Ball H J.
,
Lutterbach B
,
Hiebert S W.
, and
Licht J D.
, Mol Cell Biol, 2000 Mar, Volume 20, Issue 6, p.2075-86, (2000)
In-depth mutational analysis of the promyelocytic leukemia zinc finger BTB/POZ domain reveals motifs and residues required for biological and transcriptional functions.
,
Melnick, A
,
Ahmad K F.
,
Arai S
,
Polinger A
,
Ball H
,
Borden K L.
,
Carlile G W.
,
Prive G G.
, and
Licht J D.
, Mol Cell Biol, 2000 Sep, Volume 20, Issue 17, p.6550-67, (2000)
1999
Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia.
,
Melnick, A
, and
Licht J D.
, Blood, 1999 May 15, Volume 93, Issue 10, p.3167-215, (1999)
Identification of novel chromosomal rearrangements in acute myelogenous leukemia involving loci on chromosome 2p23, 15q22 and 17q21.
,
Melnick, A
,
Fruchtman S
,
Zelent A
,
Liu M
,
Huang Q
,
Boczkowska B
,
Calasanz M
,
Fernandez A
,
Licht J D.
, and
Najfeld V
, Leukemia, 1999 Oct, Volume 13, Issue 10, p.1534-8, (1999)
A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF.
,
Hoatlin, M E.
,
Zhi Y
,
Ball H
,
Silvey K
,
Melnick A
,
Stone S
,
Arai S
,
Hawe N
,
Owen G
,
Zelent A
, et al.
, Blood, 1999 Dec 01, Volume 94, Issue 11, p.3737-47, (1999)
The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.
,
Ball, H J.
,
Melnick A
,
Shaknovich R
,
Kohanski R A.
, and
Licht J D.
, Nucleic Acids Res, 1999 Oct 15, Volume 27, Issue 20, p.4106-13, (1999)
1996
Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.
,
Licht, J D.
,
Shaknovich R
,
English M A.
,
Melnick A
,
Li J Y.
,
Reddy J C.
,
Dong S
,
Chen S J.
,
Zelent A
, and
Waxman S
, Oncogene, 1996 Jan 18, Volume 12, Issue 2, p.323-36, (1996)
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