Found 271 results
2018
Untangling the Role of Polycomb Complexes in Chemotherapy Resistance., Duy, Cihangir, and Melnick Ari , Cancer Discov, 2018 11, Volume 8, Issue 11, p.1348-1351, (2018)
2017
BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells., Valls, Ester, Lobry Camille, Geng Huimin, Wang Ling, Cardenas Mariano, Rivas Martín, Cerchietti Leandro, Oh Philmo, Yang Shao Ning, Oswald Erin, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.506-521, (2017)
CD99 is a therapeutic target on disease stem cells in myeloid malignancies., Chung, Stephen S., Eng William S., Hu Wenhuo, Khalaj Mona, Garrett-Bakelman Francine E., Tavakkoli Montreh, Levine Ross L., Carroll Martin, Klimek Virginia M., Melnick Ari M., et al. , Sci Transl Med, 2017 01 25, Volume 9, Issue 374, (2017)
Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury., Li, Yong, Huang Xuan, Huang Shengping, He Hui, Lei Tianhua, Saaoud Fatma, Yu Xiao-Qiang, Melnick Ari, Kumar Anil, Papasian Christopher J., et al. , Signal Transduct Target Ther, 2017, Volume 2, p.17066, (2017)
Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 05, Volume 7, Issue 5, p.494-505, (2017)
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas., Jiang, Yanwen, Ortega-Molina Ana, Geng Huimin, Ying Hsia-Yuan, Hatzi Katerina, Parsa Sara, McNally Dylan, Wang Ling, Doane Ashley S., Agirre Xabier, et al. , Cancer Discov, 2017 01, Volume 7, Issue 1, p.38-53, (2017)
DNA Methylation-Based Biomarkers., Cerchietti, Leandro, and Melnick Ari , J Clin Oncol, 2017 03, Volume 35, Issue 7, p.793-795, (2017)
Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model., Du, Wei, Goldstein Rebecca, Jiang Yanwen, Aly Omar, Cerchietti Leandro, Melnick Ari, and Elemento Olivier , Cancer Res, 2017 04 15, Volume 77, Issue 8, p.1818-1830, (2017)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 08, Volume 7, Issue 8, p.868-883, (2017)
The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target., Cardenas, Mariano G., Oswald Erin, Yu Wenbo, Xue Fengtian, MacKerell Alexander D., and Melnick Ari M. , Clin Cancer Res, 2017 Feb 15, Volume 23, Issue 4, p.885-893, (2017)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 10 12, Volume 8, Issue 1, p.877, (2017)
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., Gascoyne, Randy D., Nadel Bertrand, Pasqualucci Laura, Fitzgibbon Jude, Payton Jacqueline E., Melnick Ari, Weigert Oliver, Tarte Karin, Gribben John G., Friedberg Jonathan W., et al. , Hematol Oncol, 2017 Dec, Volume 35, Issue 4, p.397-407, (2017)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
Genetic and epigenetic inactivation of controls mTORC1 and response to EZH2 inhibition in follicular lymphoma., Oricchio, Elisa, Katanayeva Natalya, Donaldson Maria Christine, Sungalee Stephanie, Pasion Joyce P., Béguelin Wendy, Battistello Elena, Sanghvi Viraj R., Jiang Man, Jiang Yanwen, et al. , Sci Transl Med, 2017 06 28, Volume 9, Issue 396, (2017)
is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)
MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 12 15, Volume 77, Issue 24, p.7038-7048, (2017)
The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells., Vu, Ly P., Pickering Brian F., Cheng Yuanming, Zaccara Sara, Nguyen Diu, Minuesa Gerard, Chou Timothy, Chow Arthur, Saletore Yogesh, MacKay Matthew, et al. , Nat Med, 2017 Nov, Volume 23, Issue 11, p.1369-1376, (2017)
Untangling the Web of Lymphoma Somatic Mutations., Teater, Matt, and Melnick Ari , Cell, 2017 10 05, Volume 171, Issue 2, p.270-272, (2017)
2016
A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia., Luskin, Marlise R., Gimotty Phyllis A., Smith Catherine, Loren Alison W., Figueroa Maria E., Harrison Jenna, Sun Zhuoxin, Tallman Martin S., Paietta Elisabeth M., Litzow Mark R., et al. , JCI Insight, 2016 Jun 16, Volume 1, Issue 9, (2016)
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas., Culjkovic-Kraljacic, Biljana, Fernando Tharu M., Marullo Rossella, Calvo-Vidal Nieves, Verma Akanksha, Yang ShaoNing, Tabbò Fabrizio, Gaudiano Marcello, Zahreddine Hiba, Goldstein Rebecca L., et al. , Blood, 2016 Feb 18, Volume 127, Issue 7, p.858-68, (2016)
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia., Chen, Zhengshan, Shojaee Seyedmehdi, Buchner Maike, Geng Huimin, Lee Jae Woong, Klemm Lars, Titz Björn, Graeber Thomas G., Park Eugene, Tan Ying Xim, et al. , Nature, 2016 06 02, Volume 534, Issue 7605, p.138, (2016)
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia., Li, Sheng, Garrett-Bakelman Francine E., Chung Stephen S., Sanders Mathijs A., Hricik Todd, Rapaport Franck, Patel Jay, Dillon Richard, Vijay Priyanka, Brown Anna L., et al. , Nat Med, 2016 07, Volume 22, Issue 7, p.792-9, (2016)
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia., Meyer, Sara E., Qin Tingting, Muench David E., Masuda Kohei, Venkatasubramanian Meenakshi, Orr Emily, Suarez Lauren, Gore Steven D., Delwel Ruud, Paietta Elisabeth, et al. , Cancer Discov, 2016 05, Volume 6, Issue 5, p.501-15, (2016)
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling., Guryanova, Olga A., Shank Kaitlyn, Spitzer Barbara, Luciani Luisa, Koche Richard P., Garrett-Bakelman Francine E., Ganzel Chezi, Durham Benjamin H., Mohanty Abhinita, Hoermann Gregor, et al. , Nat Med, 2016 12, Volume 22, Issue 12, p.1488-1495, (2016)
The epichaperome is an integrated chaperome network that facilitates tumour survival., Rodina, Anna, Wang Tai, Yan Pengrong, Gomes Erica DaGama, Dunphy Mark P. S., Pillarsetty Nagavarakishore, Koren John, Gerecitano John F., Taldone Tony, Zong Hongliang, et al. , Nature, 2016 Oct 20, Volume 538, Issue 7625, p.397-401, (2016)