Found 86 results
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Journal Article
The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 Jul, Volume 23, Issue 4, p.377-84, (2016)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms., Nischal, Sangeeta, Bhattacharyya Sanchari, Christopeit Maximilian, Yu Yiting, Zhou Li, Bhagat Tushar D., Sohal Davendra, Will Britta, Mo Yongkai, Suzuki Masako, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition., Ennishi, Daisuke, Takata Katsuyoshi, Béguelin Wendy, Duns Gerben, Mottok Anja, Farinha Pedro, Bashashati Ali, Saberi Saeed, Boyle Merrill, Meissner Barbara, et al. , Cancer Discov, 2019 Apr, Volume 9, Issue 4, p.546-563, (2019)
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., Lu, Xiangdong, Chu Chi-Shuen, Fang Terry, Rayon-Estrada Violeta, Fang Fang, Patke Alina, Qian Ye, Clarke Stephen H., Melnick Ari M., Zhang Yi, et al. , Cell Rep, 2019 Jul 09, Volume 28, Issue 2, p.472-485.e5, (2019)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region., Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al. , Immunity, 2016 Sep 20, Volume 45, Issue 3, p.497-512, (2016)
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response., Béguelin, Wendy, Teater Matt, Meydan Cem, Hoehn Kenneth B., Phillip Jude M., Soshnev Alexey A., Venturutti Leandro, Rivas Martín A., Calvo-Fernández María T., Gutierrez Johana, et al. , Cancer Cell, 2020 May 11, Volume 37, Issue 5, p.655-673.e11, (2020)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., Garrett-Bakelman, Francine E., and Melnick Ari M. , Epigenomics, 2016 Jul, Volume 8, Issue 7, p.945-57, (2016)
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., Garrett-Bakelman, Francine E., Darshi Manjula, Green Stefan J., Gur Ruben C., Lin Ling, Macias Brandon R., McKenna Miles J., Meydan Cem, Mishra Tejaswini, Nasrini Jad, et al. , Science, 2019 Apr 12, Volume 364, Issue 6436, (2019)
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling., Park-Min, Kyung-Hyun, Lee Eun Young, Moskowitz Neal K., Lim Elisha, Lee Sun-Kyeong, Lorenzo Joseph A., Huang ChuanXin, Melnick Ari M., P Purdue Edward, Goldring Steven R., et al. , J Bone Miner Res, 2013 Jan, Volume 28, Issue 1, p.135-49, (2013)
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes., Bunting, Karen L., and Melnick Ari M. , Curr Opin Immunol, 2013 Jun, Volume 25, Issue 3, p.339-46, (2013)
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., Li, Meng, Chiang Ying-Ling, Lyssiotis Costas A., Teater Matthew R., Hong Jun Young, Shen Hao, Wang Ling, Hu Jing, Jing Hui, Chen Zhengming, et al. , Cancer Cell, 2019 Jun 10, Volume 35, Issue 6, p.916-931.e9, (2019)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., Fabre, Marie-Sophie, Stanton Nicole M., Slatter Tania L., Lee Samuel, Senanayake Dinindu, Gordon Rosemary M. A., M Castro Leticia, Rowe Matthew R., Taha Ahmad, Royds Janice A., et al. , PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)
Oncogene-mediated alterations in chromatin conformation., Rickman, David S., T Soong David, Moss Benjamin, Mosquera Juan Miguel, Dlabal Jan, Terry Stéphane, MacDonald Theresa Y., Tripodi Joseph, Bunting Karen, Najfeld Vesna, et al. , Proc Natl Acad Sci U S A, 2012 Jun 05, Volume 109, Issue 23, p.9083-8, (2012)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival., Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al. , Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML., Duy, Cihangir, Teater Matt, Garrett-Bakelman Francine E., Lee Tak C., Meydan Cem, Glass Jacob L., Li Meng, Hellmuth Johannes C., Mohammad Helai P., Smitheman Kimberly N., et al. , Cancer Discov, 2019 Jul, Volume 9, Issue 7, p.872-889, (2019)
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma., Cardenas, Mariano G., Yu Wenbo, Béguelin Wendy, Teater Matthew R., Geng Huimin, Goldstein Rebecca L., Oswald Erin, Hatzi Katerina, Yang Shao-Ning, Cohen Joanna, et al. , J Clin Invest, 2016 Sep 01, Volume 126, Issue 9, p.3351-62, (2016)
A roadmap for discovery and translation in lymphoma., Weinstock, David M., Dalla-Favera Riccardo, Gascoyne Randy D., Leonard John P., Levy Ronald, Lossos Izidore S., Melnick Ari M., Nowakowski Grzegorz S., Press Oliver W., Savage Kerry J., et al. , Blood, 2015 Mar 26, Volume 125, Issue 13, p.2175-7, (2015)
Role of chromosomal architecture in germinal center B cells and lymphomagenesis., Rivas, Martín A., and Melnick Ari M. , Curr Opin Hematol, 2019 Jul, Volume 26, Issue 4, p.294-302, (2019)
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain., Nandi, Sayan, Chandramohan Dhruva, Fioriti Luana, Melnick Ari M., Hébert Jean M., Mason Christopher E., Rajasethupathy Priyamvada, and Kandel Eric R. , Proc Natl Acad Sci U S A, 2016 Nov 08, Volume 113, Issue 45, p.12697-12702, (2016)
Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma., Mondello, Patrizia, Tadros Saber, Teater Matt, Fontan Lorena, Chang Aaron Y., Jain Neeraj, Yang Haopeng, Singh Shailbala, Ying Hsia-Yuan, Chu Chi-Shuen, et al. , Cancer Discov, 2020 Mar, Volume 10, Issue 3, p.440-459, (2020)
Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions., Butler, Daniel J., Mozsary Christopher, Meydan Cem, Danko David, Foox Jonathan, Rosiene Joel, Shaiber Alon, Afshinnekoo Ebrahim, MacKay Matthew, Sedlazeck Fritz J., et al. , bioRxiv, 2020 May 01, (2020)
SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents., Fiskus, Warren, Coothankandaswamy Veena, Chen Jianguang, Ma Hongwei, Ha Kyungsoo, Saenz Dyana T., Krieger Stephanie S., Mill Christopher P., Sun Baohua, Huang Peng, et al. , Cancer Res, 2016 Sep 15, Volume 76, Issue 18, p.5467-78, (2016)
Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease., Paz, Katelyn, Flynn Ryan, Du Jing, Qi Jun, Luznik Leo, Maillard Ivan, MacDonald Kelli P., Hill Geoffrey R., Serody Jonathan S., Murphy William J., et al. , Blood, 2019 Jan 03, Volume 133, Issue 1, p.94-99, (2019)