Found 271 results
2010
BCL6 is critical for the development of a diverse primary B cell repertoire., Duy, Cihangir, J Yu Jessica, Nahar Rahul, Swaminathan Srividya, Kweon Soo-Mi, Polo Jose M., Valls Ester, Klemm Lars, Shojaee Seyedmehdi, Cerchietti Leandro, et al. , J Exp Med, 2010 Jun 07, Volume 207, Issue 6, p.1209-21, (2010)
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy., Cerchietti, Leandro C., Hatzi Katerina, Caldas-Lopes Eloisi, Yang Shao Ning, Figueroa Maria E., Morin Ryan D., Hirst Martin, Mendez Lourdes, Shaknovich Rita, Cole Philip A., et al. , J Clin Invest, 2010 Dec 01, Volume 120, Issue 12, p.4569-82, (2010)
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells., Polo, Jose M., Liu Susanna, Figueroa Maria Eugenia, Kulalert Warakorn, Eminli Sarah, Tan Kah Yong, Apostolou Effie, Stadtfeld Matthias, Li Yushan, Shioda Toshi, et al. , Nat Biotechnol, 2010 Aug, Volume 28, Issue 8, p.848-55, (2010)
DNA methylation signatures define molecular subtypes of diffuse large B-cell lymphoma., Shaknovich, Rita, Geng Huimin, Johnson Nathalie A., Tsikitas Lucas, Cerchietti Leandro, Greally John M., Gascoyne Randy D., Elemento Olivier, and Melnick Ari , Blood, 2010 Nov 18, Volume 116, Issue 20, p.e81-9, (2010)
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia., Figueroa, Maria E., Lugthart Sanne, Li Yushan, Erpelinck-Verschueren Claudia, Deng Xutao, Christos Paul J., Schifano Elizabeth, Booth James, van Putten Wim, Skrabanek Lucy, et al. , Cancer Cell, 2010 Jan 19, Volume 17, Issue 1, p.13-27, (2010)
DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis., Shah, Mrinal Y., Vasanthakumar Aparna, Barnes Natalie Y., Figueroa Maria E., Kamp Anna, Hendrick Christopher, Ostler Kelly R., Davis Elizabeth M., Lin Shang, Anastasi John, et al. , Cancer Res, 2010 Jul 15, Volume 70, Issue 14, p.5840-50, (2010)
Epigenetics in AML., Melnick, Ari M. , Best Pract Res Clin Haematol, 2010 Dec, Volume 23, Issue 4, p.463-8, (2010)
Expression of p21 protein predicts clinical outcome in DLBCL patients older than 60 years treated with R-CHOP but not CHOP: a prospective ECOG and Southwest Oncology Group correlative study on E4494., Winter, Jane N., Li Shuli, Aurora Vikas, Variakojis Daina, Nelson Beverly, Krajewska Maryla, Zhang Lijun, Habermann Thomas M., Fisher Richard I., Macon William R., et al. , Clin Cancer Res, 2010 Apr 15, Volume 16, Issue 8, p.2435-42, (2010)
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis., Velichutina, Irina, Shaknovich Rita, Geng Huimin, Johnson Nathalie A., Gascoyne Randy D., Melnick Ari M., and Elemento Olivier , Blood, 2010 Dec 09, Volume 116, Issue 24, p.5247-55, (2010)
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis., Murphy, Mark W., Sarver Aaron L., Rice Daren, Hatzi Katerina, Ye Kenny, Melnick Ari, Heckert Leslie L., Zarkower David, and Bardwell Vivian J. , Proc Natl Acad Sci U S A, 2010 Jul 27, Volume 107, Issue 30, p.13360-5, (2010)
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma., Leshchenko, Violetta V., Kuo Pei-Yu, Shaknovich Rita, Yang David T., Gellen Tobias, Petrich Adam, Yu Yiting, Remache Yvonne, Weniger Marc A., Rafiq Sarwish, et al. , Blood, 2010 Aug 19, Volume 116, Issue 7, p.1025-34, (2010)
HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes., Shaknovich, Rita, Figueroa Maria E., and Melnick Ari , Methods Mol Biol, 2010, Volume 632, p.191-201, (2010)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
NCI first International Workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the committee on the biological considerations of hematological relapse following allogeneic stem c, Cairo, Mitchell S., Jordan Craig T., Maley Carlo C., Chao Clifford, Melnick Ari, Armstrong Scott A., Shlomchik Warren, Molldrem Jeff, Ferrone Soldano, Mackall Crystal, et al. , Biol Blood Marrow Transplant, 2010 Jun, Volume 16, Issue 6, p.709-28, (2010)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting., Schafer, Eric, Irizarry Rafael, Negi Sandeep, McIntyre Emily, Small Donald, Figueroa Maria E., Melnick Ari, and Brown Patrick , Blood, 2010 Jun 10, Volume 115, Issue 23, p.4798-809, (2010)
Response to second-line therapy defines the potential for cure in patients with recurrent diffuse large B-cell lymphoma: implications for the development of novel therapeutic strategies., Elstrom, Rebecca L., Martin Peter, Ostrow Katya, Barrientos Jacqueline, Chadburn Amy, Furman Richard, Ruan Jia, Shore Tsiporah, Schuster Michael, Cerchietti Leandro, et al. , Clin Lymphoma Myeloma Leuk, 2010 Jun, Volume 10, Issue 3, p.192-6, (2010)
SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells., Hammerich-Hille, Stephanie, Kaipparettu Benny A., Tsimelzon Anna, Creighton Chad J., Jiang Shiming, Polo Jose M., Melnick Ari, Meyer Rene, and Oesterreich Steffi , J Biol Chem, 2010 Feb 05, Volume 285, Issue 6, p.3608-3616, (2010)
A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo., Cerchietti, Leandro C., Ghetu Alexandru F., Zhu Xiao, Da Silva Gustavo F., Zhong Shijun, Matthews Marilyn, Bunting Karen L., Polo Jose M., Farès Christophe, Arrowsmith Cheryl H., et al. , Cancer Cell, 2010 Apr 13, Volume 17, Issue 4, p.400-11, (2010)
2011
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q., Zhou, Li, Opalinska Joanna, Sohal Davendra, Yu Yiting, Mo Yongkai, Bhagat Tushar, Abdel-Wahab Omar, Fazzari Melissa, Figueroa Maria, Alencar Cristina, et al. , J Biol Chem, 2011 Jul 15, Volume 286, Issue 28, p.25211-23, (2011)
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90., Moulick, Kamalika, Ahn James H., Zong Hongliang, Rodina Anna, Cerchietti Leandro, DaGama Erica M. Gomes, Caldas-Lopes Eloisi, Beebe Kristin, Perna Fabiana, Hatzi Katerina, et al. , Nat Chem Biol, 2011 Sep 25, Volume 7, Issue 11, p.818-26, (2011)
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition., Duy, Cihangir, Hurtz Christian, Shojaee Seyedmehdi, Cerchietti Leandro, Geng Huimin, Swaminathan Srividya, Klemm Lars, Kweon Soo-Mi, Nahar Rahul, Braig Melanie, et al. , Nature, 2011 May 19, Volume 473, Issue 7347, p.384-8, (2011)
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia., Hurtz, Christian, Hatzi Katerina, Cerchietti Leandro, Braig Melanie, Park Eugene, Kim Yong-mi, Herzog Sebastian, Ramezani-Rad Parham, Jumaa Hassan, Müller Martin C., et al. , J Exp Med, 2011 Oct 24, Volume 208, Issue 11, p.2163-74, (2011)
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation., Shaknovich, Rita, Cerchietti Leandro, Tsikitas Lucas, Kormaksson Matthias, De Subhajyoti, Figueroa Maria E., Ballon Gianna, Yang Shao Ning, Weinhold Nils, Reimers Mark, et al. , Blood, 2011 Sep 29, Volume 118, Issue 13, p.3559-69, (2011)