Found 271 results
2016
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis., Béguelin, Wendy, Teater Matt, Gearhart Micah D., Fernández María Teresa Cal, Goldstein Rebecca L., Cardenas Mariano G., Hatzi Katerina, Rosen Monica, Shen Hao, Corcoran Connie M., et al. , Cancer Cell, 2016 08 08, Volume 30, Issue 2, p.197-213, (2016)
General Biomarker Recommendations for Lymphoma., Rimsza, Lisa, Fedoriw Yuri, Staudt Louis M., Melnick Ari, Gascoyne Randy, Crump Michael, Baizer Lawrence, Fu Kai, Hsi Eric, Chan John W. C., et al. , J Natl Cancer Inst, 2016 12, Volume 108, Issue 12, (2016)
Genetic and epigenetic heterogeneity in acute myeloid leukemia., Li, Sheng, Mason Christopher E., and Melnick Ari , Curr Opin Genet Dev, 2016 02, Volume 36, p.100-6, (2016)
A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations., Han, Dali, Lu Xingyu, Shih Alan H., Nie Ji, You Qiancheng, Xu Meng Michelle, Melnick Ari M., Levine Ross L., and He Chuan , Mol Cell, 2016 08 18, Volume 63, Issue 4, p.711-719, (2016)
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics., Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al. , Nat Commun, 2016 06 14, Volume 7, p.11889, (2016)
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas., Bayliss, Jill, Mukherjee Piali, Lu Chao, Jain Siddhant U., Chung Chan, Martinez Daniel, Sabari Benjamin, Margol Ashley S., Panwalkar Pooja, Parolia Abhijit, et al. , Sci Transl Med, 2016 11 23, Volume 8, Issue 366, p.366ra161, (2016)
The many layers of epigenetic dysfunction in B-cell lymphomas., Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M. , Curr Opin Hematol, 2016 07, Volume 23, Issue 4, p.377-84, (2016)
miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis., Kozloski, Goldi A., Jiang Xiaoyu, Bhatt Shruti, Ruiz Jose, Vega Francisco, Shaknovich Rita, Melnick Ari, and Lossos Izidore S. , Blood, 2016 06 09, Volume 127, Issue 23, p.2856-66, (2016)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region., Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al. , Immunity, 2016 09 20, Volume 45, Issue 3, p.497-512, (2016)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., Garrett-Bakelman, Francine E., and Melnick Ari M. , Epigenomics, 2016 07, Volume 8, Issue 7, p.945-57, (2016)
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma., Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al. , Blood, 2016 07 07, Volume 128, Issue 1, p.82-92, (2016)
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells., Shojaee, Seyedmehdi, Chan Lai N., Buchner Maike, Cazzaniga Valeria, Cosgun Kadriye Nehir, Geng Huimin, Qiu Yi Hua, von Minden Marcus Dühren, Ernst Thomas, Hochhaus Andreas, et al. , Nat Med, 2016 Apr, Volume 22, Issue 4, p.379-87, (2016)
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma., Cardenas, Mariano G., Yu Wenbo, Béguelin Wendy, Teater Matthew R., Geng Huimin, Goldstein Rebecca L., Oswald Erin, Hatzi Katerina, Yang Shao-Ning, Cohen Joanna, et al. , J Clin Invest, 2016 09 01, Volume 126, Issue 9, p.3351-62, (2016)
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2016 06 07, Volume 22, Issue 6, p.578-9, (2016)
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain., Nandi, Sayan, Chandramohan Dhruva, Fioriti Luana, Melnick Ari M., Hébert Jean M., Mason Christopher E., Rajasethupathy Priyamvada, and Kandel Eric R. , Proc Natl Acad Sci U S A, 2016 Nov 08, Volume 113, Issue 45, p.12697-12702, (2016)
Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma., Dupont, Thibault, Yang Shao Ning, Patel Jayeshkumar, Hatzi Katerina, Malik Alka, Tam Wayne, Martin Peter, Leonard John, Melnick Ari, and Cerchietti Leandro , Oncotarget, 2016 Jan 19, Volume 7, Issue 3, p.3520-32, (2016)
SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents., Fiskus, Warren, Coothankandaswamy Veena, Chen Jianguang, Ma Hongwei, Ha Kyungsoo, Saenz Dyana T., Krieger Stephanie S., Mill Christopher P., Sun Baohua, Huang Peng, et al. , Cancer Res, 2016 09 15, Volume 76, Issue 18, p.5467-78, (2016)
2015
BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms., Hatzi, Katerina, J Nance Philip, Kroenke Mark A., Bothwell Marcella, Haddad Elias K., Melnick Ari, and Crotty Shane , J Exp Med, 2015 Apr 06, Volume 212, Issue 4, p.539-53, (2015)
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID., Dominguez, Pilar M., Teater Matt, Chambwe Nyasha, Kormaksson Matthias, Redmond David, Ishii Jennifer, Vuong Bao, Chaudhuri Jayanta, Melnick Ari, Vasanthakumar Aparna, et al. , Cell Rep, 2015 Sep 29, Volume 12, Issue 12, p.2086-98, (2015)
Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis., Viny, Aaron D., Ott Christopher J., Spitzer Barbara, Rivas Martín, Meydan Cem, Papalexi Efthymia, Yelin Dana, Shank Kaitlyn, Reyes Jaime, Chiu April, et al. , J Exp Med, 2015 Oct 19, Volume 212, Issue 11, p.1819-32, (2015)
Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., Noh, Kyung-Min, Wang Haibo, Kim Hyunjae R., Wenderski Wendy, Fang Fang, Li Charles H., Dewell Scott, Hughes Stephen H., Melnick Ari M., Patel Dinshaw J., et al. , Mol Cell, 2015 Jul 02, Volume 59, Issue 1, p.89-103, (2015)
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution., Garrett-Bakelman, Francine E., Sheridan Caroline K., Kacmarczyk Thadeous J., Ishii Jennifer, Betel Doron, Alonso Alicia, Mason Christopher E., Figueroa Maria E., and Melnick Ari M. , J Vis Exp, 2015 Feb 24, Issue 96, p.e52246, (2015)
The epigenetic basis of diffuse large B-cell lymphoma., Jiang, Yanwen, and Melnick Ari , Semin Hematol, 2015 Apr, Volume 52, Issue 2, p.86-96, (2015)
Epigenomic evolution in diffuse large B-cell lymphomas., Pan, Heng, Jiang Yanwen, Boi Michela, Tabbò Fabrizio, Redmond David, Nie Kui, Ladetto Marco, Chiappella Annalisa, Cerchietti Leandro, Shaknovich Rita, et al. , Nat Commun, 2015 Apr 20, Volume 6, p.6921, (2015)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)