Found 271 results
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Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)
SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents., Fiskus, Warren, Coothankandaswamy Veena, Chen Jianguang, Ma Hongwei, Ha Kyungsoo, Saenz Dyana T., Krieger Stephanie S., Mill Christopher P., Sun Baohua, Huang Peng, et al. , Cancer Res, 2016 Sep 15, Volume 76, Issue 18, p.5467-78, (2016)
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities., Flümann, Ruth, Rehkämper Tim, Nieper Pascal, Pfeiffer Pauline, Holzem Alessandra, Klein Sebastian, Bhatia Sanil, Kochanek Moritz, Kisis Ilmars, Pelzer Benedikt W., et al. , Blood Cancer Discov, 2021 Jan, Volume 2, Issue 1, p.70-91, (2021)
Discovering what makes STAT signaling TYK in T-ALL., Fontan, Lorena, and Melnick Ari , Cancer Discov, 2013 May, Volume 3, Issue 5, p.494-6, (2013)
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth., Fontan, Lorena, Qiao Qi, Hatcher John M., Casalena Gabriella, Us Ilkay, Teater Matt, Durant Matt, Du Guangyan, Xia Min, Bilchuk Natalia, et al. , J Clin Invest, 2018 Oct 01, Volume 128, Issue 10, p.4397-4412, (2018)
Molecular pathways: targeting MALT1 paracaspase activity in lymphoma., Fontan, Lorena, and Melnick Ari , Clin Cancer Res, 2013 Dec 15, Volume 19, Issue 24, p.6662-8, (2013)
Targeting lymphomas through MALT1 inhibition., Fontan, Lorena, and Melnick Ari , Oncotarget, 2012 Dec, Volume 3, Issue 12, p.1493-4, (2012)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
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The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight., Garrett-Bakelman, Francine E., Darshi Manjula, Green Stefan J., Gur Ruben C., Lin Ling, Macias Brandon R., McKenna Miles J., Meydan Cem, Mishra Tejaswini, Nasrini Jad, et al. , Science, 2019 Apr 12, Volume 364, Issue 6436, (2019)
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution., Garrett-Bakelman, Francine E., Sheridan Caroline K., Kacmarczyk Thadeous J., Ishii Jennifer, Betel Doron, Alonso Alicia, Mason Christopher E., Figueroa Maria E., and Melnick Ari M. , J Vis Exp, 2015 Feb 24, Issue 96, p.e52246, (2015)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation., Garrett-Bakelman, Francine E., and Melnick Ari M. , Epigenomics, 2016 Jul, Volume 8, Issue 7, p.945-57, (2016)
Differentiation therapy for IDH1/2 mutant malignancies., Garrett-Bakelman, Francine E., and Melnick Ari M. , Cell Res, 2013 Aug, Volume 23, Issue 8, p.975-7, (2013)
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., Gascoyne, Randy D., Nadel Bertrand, Pasqualucci Laura, Fitzgibbon Jude, Payton Jacqueline E., Melnick Ari, Weigert Oliver, Tarte Karin, Gribben John G., Friedberg Jonathan W., et al. , Hematol Oncol, 2017 Dec, Volume 35, Issue 4, p.397-407, (2017)
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia., Geng, Huimin, Brennan Sarah, Milne Thomas A., Chen Wei-Yi, Li Yushan, Hurtz Christian, Kweon Soo-Mi, Zickl Lynette, Shojaee Seyedmehdi, Neuberg Donna, et al. , Cancer Discov, 2012 Nov, Volume 2, Issue 11, p.1004-23, (2012)
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia., Geng, Huimin, Hurtz Christian, Lenz Kyle B., Chen Zhengshan, Baumjohann Dirk, Thompson Sarah, Goloviznina Natalya A., Chen Wei-Yi, Huan Jianya, LaTocha Dorian, et al. , Cancer Cell, 2015 Mar 09, Volume 27, Issue 3, p.409-25, (2015)
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer., Ghetu, Alexandru F., Corcoran Connie M., Cerchietti Leandro, Bardwell Vivian J., Melnick Ari, and Prive Gilbert G. , Mol Cell, 2008 Feb 15, Volume 29, Issue 3, p.384-91, (2008)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 Aug, Volume 7, Issue 8, p.868-883, (2017)
CG dinucleotide clustering is a species-specific property of the genome., Glass, Jacob L., Thompson Reid F., Khulan Batbayar, Figueroa Maria E., Olivier Emmanuel N., Oakley Erin J., Van Zant Gary, Bouhassira Eric E., Melnick Ari, Golden Aaron, et al. , Nucleic Acids Res, 2007, Volume 35, Issue 20, p.6798-807, (2007)
The Impact of Heterogeneity on Single-Cell Sequencing., Goldman, Samantha L., MacKay Matthew, Afshinnekoo Ebrahim, Melnick Ari M., Wu Shuxiu, and Mason Christopher E. , Front Genet, 2019, Volume 10, p.8, (2019)
Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al. , J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)
Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization., Gomes, Ana P., Ilter Didem, Low Vivien, Rosenzweig Adam, Shen Zih-Jie, Schild Tanya, Rivas Martín A., Er Ekrem E., McNally Dylan R., Mutvei Anders P., et al. , Cancer Cell, 2019 Oct 14, Volume 36, Issue 4, p.402-417.e13, (2019)
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900., Gönen, Mithat, Sun Zhuoxin, Figueroa Maria E., Patel Jay P., Abdel-Wahab Omar, Racevskis Janis, Ketterling Rhett P., Fernandez Hugo, Rowe Jacob M., Tallman Martin S., et al. , Blood, 2012 Sep 13, Volume 120, Issue 11, p.2297-306, (2012)
Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma., Green, Michael R., Vicente-Dueñas Carolina, Romero-Camarero Isabel, Liu Chih Long, Dai Bo, González-Herrero Inés, García-Ramírez Idoia, Alonso-Escudero Esther, Iqbal Javeed, Chan Wing C., et al. , Nat Commun, 2014 Jun 02, Volume 5, p.3904, (2014)
Enhancer of zeste homolog 2 (EZH2) inhibitors., Gulati, Nitya, Béguelin Wendy, and Giulino-Roth Lisa , Leuk Lymphoma, 2018 Jul, Volume 59, Issue 7, p.1574-1585, (2018)