Found 271 results
Journal Article
Emerging epigenetic-modulating therapies in lymphoma., Sermer, David, Pasqualucci Laura, Wendel Hans-Guido, Melnick Ari, and Younes Anas , Nat Rev Clin Oncol, 2019 Aug, Volume 16, Issue 8, p.494-507, (2019)
Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., Noh, Kyung-Min, Wang Haibo, Kim Hyunjae R., Wenderski Wendy, Fang Fang, Li Charles H., Dewell Scott, Hughes Stephen H., Melnick Ari M., Patel Dinshaw J., et al. , Mol Cell, 2018 Feb 01, Volume 69, Issue 3, p.533, (2018)
Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., Noh, Kyung-Min, Wang Haibo, Kim Hyunjae R., Wenderski Wendy, Fang Fang, Li Charles H., Dewell Scott, Hughes Stephen H., Melnick Ari M., Patel Dinshaw J., et al. , Mol Cell, 2015 Jul 02, Volume 59, Issue 1, p.89-103, (2015)
Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution., Garrett-Bakelman, Francine E., Sheridan Caroline K., Kacmarczyk Thadeous J., Ishii Jennifer, Betel Doron, Alonso Alicia, Mason Christopher E., Figueroa Maria E., and Melnick Ari M. , J Vis Exp, 2015 Feb 24, Issue 96, p.e52246, (2015)
Enhancer of zeste homolog 2 (EZH2) inhibitors., Gulati, Nitya, Béguelin Wendy, and Giulino-Roth Lisa , Leuk Lymphoma, 2018 Jul, Volume 59, Issue 7, p.1574-1585, (2018)
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma., Oricchio, Elisa, Nanjangud Gouri, Wolfe Andrew L., Schatz Jonathan H., Mavrakis Konstantinos J., Jiang Man, Liu Xiaoping, Bruno Joanne, Heguy Adriana, Olshen Adam B., et al. , Cell, 2011 Oct 28, Volume 147, Issue 3, p.554-64, (2011)
The epichaperome is an integrated chaperome network that facilitates tumour survival., Rodina, Anna, Wang Tai, Yan Pengrong, Gomes Erica DaGama, Dunphy Mark P. S., Pillarsetty Nagavarakishore, Koren John, Gerecitano John F., Taldone Tony, Zong Hongliang, et al. , Nature, 2016 Oct 20, Volume 538, Issue 7625, p.397-401, (2016)
The epigenetic basis of diffuse large B-cell lymphoma., Jiang, Yanwen, and Melnick Ari , Semin Hematol, 2015 Apr, Volume 52, Issue 2, p.86-96, (2015)
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 Aug, Volume 7, Issue 8, p.868-883, (2017)
Epigenetic Mechanisms in Leukemias and Lymphomas., Duy, Cihangir, Béguelin Wendy, and Melnick Ari , Cold Spring Harb Perspect Med, 2020 Dec 01, Volume 10, Issue 12, (2020)
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression., Lin, Pei-Chun, Chiu Ya-Lin, Banerjee Samprit, Park Kyung, Mosquera Juan Miguel, Giannopoulou Eugenia, Alves Pedro, Tewari Ashutosh K., Gerstein Mark B., Beltran Himisha, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1232-44, (2013)
Epigenetic therapy leaps ahead with specific targeting of EZH2., Melnick, Ari , Cancer Cell, 2012 Nov 13, Volume 22, Issue 5, p.569-70, (2012)
Epigenetics and B-cell lymphoma., Shaknovich, Rita, and Melnick Ari , Curr Opin Hematol, 2011 Jul, Volume 18, Issue 4, p.293-9, (2011)
Epigenetics in AML., Melnick, Ari M. , Best Pract Res Clin Haematol, 2010 Dec, Volume 23, Issue 4, p.463-8, (2010)
Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents., Santini, Valeria, Melnick Ari, Maciejewski Jaroslaw P., Duprez Estelle, Nervi Clara, Cocco Lucio, Ford Kevin G., and Mufti Ghulam , Crit Rev Oncol Hematol, 2013 Nov, Volume 88, Issue 2, p.231-45, (2013)
Epigenomic evolution in diffuse large B-cell lymphomas., Pan, Heng, Jiang Yanwen, Boi Michela, Tabbò Fabrizio, Redmond David, Nie Kui, Ladetto Marco, Chiappella Annalisa, Cerchietti Leandro, Shaknovich Rita, et al. , Nat Commun, 2015 Apr 20, Volume 6, p.6921, (2015)
Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)
The ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger protein., Melnick, A M., Westendorf J J., Polinger A, Carlile G W., Arai S, Ball H J., Lutterbach B, Hiebert S W., and Licht J D. , Mol Cell Biol, 2000 Mar, Volume 20, Issue 6, p.2075-86, (2000)
ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein., Chevallier, Nathalie, Corcoran Connie M., Lennon Christine, Hyjek Elizabeth, Chadburn Amy, Bardwell Vivian J., Licht Jonathan D., and Melnick Ari , Blood, 2004 Feb 15, Volume 103, Issue 4, p.1454-63, (2004)
Ex vivo synthetic immune tissues with T cell signals for differentiating antigen-specific, high affinity germinal center B cells., Purwada, Alberto, Shah Shivem B., Béguelin Wendy, August Avery, Melnick Ari M., and Singh Ankur , Biomaterials, 2019 Apr, Volume 198, p.27-36, (2019)
The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target., Cardenas, Mariano G., Oswald Erin, Yu Wenbo, Xue Fengtian, MacKerell Alexander D., and Melnick Ari M. , Clin Cancer Res, 2017 Feb 15, Volume 23, Issue 4, p.885-893, (2017)
Expression of p21 protein predicts clinical outcome in DLBCL patients older than 60 years treated with R-CHOP but not CHOP: a prospective ECOG and Southwest Oncology Group correlative study on E4494., Winter, Jane N., Li Shuli, Aurora Vikas, Variakojis Daina, Nelson Beverly, Krajewska Maryla, Zhang Lijun, Habermann Thomas M., Fisher Richard I., Macon William R., et al. , Clin Cancer Res, 2010 Apr 15, Volume 16, Issue 8, p.2435-42, (2010)
An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming?, Li, Meng, and Melnick Ari M. , Cancer Discov, 2019 Sep, Volume 9, Issue 9, p.1158-1160, (2019)
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis., Béguelin, Wendy, Teater Matt, Gearhart Micah D., Fernández María Teresa Cal, Goldstein Rebecca L., Cardenas Mariano G., Hatzi Katerina, Rosen Monica, Shen Hao, Corcoran Connie M., et al. , Cancer Cell, 2016 Aug 08, Volume 30, Issue 2, p.197-213, (2016)
EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 Oct 12, Volume 8, Issue 1, p.877, (2017)