Found 271 results
2011
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma., Oricchio, Elisa, Nanjangud Gouri, Wolfe Andrew L., Schatz Jonathan H., Mavrakis Konstantinos J., Jiang Man, Liu Xiaoping, Bruno Joanne, Heguy Adriana, Olshen Adam B., et al. , Cell, 2011 Oct 28, Volume 147, Issue 3, p.554-64, (2011)
Epigenetics and B-cell lymphoma., Shaknovich, Rita, and Melnick Ari , Curr Opin Hematol, 2011 Jul, Volume 18, Issue 4, p.293-9, (2011)
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas., Cerchietti, Leandro, Damm-Welk Christine, Vater Inga, Klapper Wolfram, Harder Lana, Pott Christiane, Yang Shao Ning, Reiter Alfred, Siebert Reiner, Melnick Ari, et al. , PLoS One, 2011 Apr 08, Volume 6, Issue 4, p.e18436, (2011)
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation., Wang, Lan, Gural Alexander, Sun Xiao-Jian, Zhao Xinyang, Perna Fabiana, Huang Gang, Hatlen Megan A., Vu Ly, Liu Fan, Xu Haiming, et al. , Science, 2011 Aug 05, Volume 333, Issue 6043, p.765-9, (2011)
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC., Nahar, Rahul, Ramezani-Rad Parham, Mossner Maximilian, Duy Cihangir, Cerchietti Leandro, Geng Huimin, Dovat Sinisa, Jumaa Hassan, B Ye Hilda, Melnick Ari, et al. , Blood, 2011 Oct 13, Volume 118, Issue 15, p.4174-8, (2011)
SYK inhibition and response prediction in diffuse large B-cell lymphoma., Cheng, Shuhua, Coffey Greg, X Zhang Hannah, Shaknovich Rita, Song Zibo, Lu Pin, Pandey Anjali, Melnick Ari M., Sinha Uma, and Y Wang Lynn , Blood, 2011 Dec 08, Volume 118, Issue 24, p.6342-52, (2011)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Moran-Crusio, Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, et al. , Cancer Cell, 2011 Jul 12, Volume 20, Issue 1, p.11-24, (2011)
Widespread hypomethylation occurs early and synergizes with gene amplification during esophageal carcinogenesis., Alvarez, Hector, Opalinska Joanna, Zhou Li, Sohal Davendra, Fazzari Melissa J., Yu Yiting, Montagna Christina, Montgomery Elizabeth A., Canto Marcia, Dunbar Kerry B., et al. , PLoS Genet, 2011 Mar, Volume 7, Issue 3, p.e1001356, (2011)
2012
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia., Akalin, Altuna, Garrett-Bakelman Francine E., Kormaksson Matthias, Busuttil Jennifer, Zhang Lu, Khrebtukova Irina, Milne Thomas A., Huang Yongsheng, Biswas Debabrata, Hess Jay L., et al. , PLoS Genet, 2012, Volume 8, Issue 6, p.e1002781, (2012)
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis., Barish, Grant D., Yu Ruth T., Karunasiri Malith S., Becerra Diana, Kim Jason, Tseng Tiffany W., Tai Li-Jung, Leblanc Matthias, Diehl Cody, Cerchietti Leandro, et al. , Cell Metab, 2012 Apr 04, Volume 15, Issue 4, p.554-62, (2012)
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900., Gönen, Mithat, Sun Zhuoxin, Figueroa Maria E., Patel Jay P., Abdel-Wahab Omar, Racevskis Janis, Ketterling Rhett P., Fernandez Hugo, Rowe Jacob M., Tallman Martin S., et al. , Blood, 2012 Sep 13, Volume 120, Issue 11, p.2297-306, (2012)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
Epigenetic therapy leaps ahead with specific targeting of EZH2., Melnick, Ari , Cancer Cell, 2012 Nov 13, Volume 22, Issue 5, p.569-70, (2012)
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., Jiang, Yanwen, T Soong David, Wang Ling, Melnick Ari M., and Elemento Olivier , PLoS One, 2012, Volume 7, Issue 7, p.e40332, (2012)
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia., Kawahara, Masahiro, Pandolfi Ashley, Bartholdy Boris, Barreyro Laura, Will Britta, Roth Michael, Okoye-Okafor Ujunwa C., Todorova Tihomira I., Figueroa Maria E., Melnick Ari, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.194-208, (2012)
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma., Cubedo, Elena, Gentles Andrew J., Huang ChuanXin, Natkunam Yasodha, Bhatt Shruti, Lu Xiaoqing, Jiang Xiaoyu, Romero-Camarero Isabel, Freud Aharon, Zhao Shuchun, et al. , Blood, 2012 Jun 07, Volume 119, Issue 23, p.5478-91, (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Sasaki, Masato, Knobbe Christiane B., Munger Joshua C., Lind Evan F., Brenner Dirk, Brüstle Anne, Harris Isaac S., Holmes Roxanne, Wakeham Andrew, Haight Jillian, et al. , Nature, 2012 Aug 30, Volume 488, Issue 7413, p.656-9, (2012)
Incidence and clinical implications of ATM aberrations in chronic lymphocytic leukemia., Ouillette, Peter, Li Jinghui, Shaknovich Rita, Li Yifeng, Melnick Ari, Shedden Kerby, and Malek Sami N. , Genes Chromosomes Cancer, 2012 Dec, Volume 51, Issue 12, p.1125-32, (2012)
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia., Geng, Huimin, Brennan Sarah, Milne Thomas A., Chen Wei-Yi, Li Yushan, Hurtz Christian, Kweon Soo-Mi, Zickl Lynette, Shojaee Seyedmehdi, Neuberg Donna, et al. , Cancer Discov, 2012 Nov, Volume 2, Issue 11, p.1004-23, (2012)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles., Akalin, Altuna, Kormaksson Matthias, Li Sheng, Garrett-Bakelman Francine E., Figueroa Maria E., Melnick Ari, and Mason Christopher E. , Genome Biol, 2012 Oct 03, Volume 13, Issue 10, p.R87, (2012)
A molecular roadmap of reprogramming somatic cells into iPS cells., Polo, Jose M., Anderssen Endre, Walsh Ryan M., Schwarz Benjamin A., Nefzger Christian M., Lim Sue Mei, Borkent Marti, Apostolou Effie, Alaei Sara, Cloutier Jennifer, et al. , Cell, 2012 Dec 21, Volume 151, Issue 7, p.1617-32, (2012)
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia., Ribeiro, Ana Flávia Ti, Pratcorona Marta, Erpelinck-Verschueren Claudia, Rockova Veronika, Sanders Mathijs, Abbas Saman, Figueroa Maria E., Zeilemaker Annelieke, Melnick Ari, Löwenberg Bob, et al. , Blood, 2012 Jun 14, Volume 119, Issue 24, p.5824-31, (2012)