Found 271 results
Journal Article
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation., Béguelin, Wendy, Popovic Relja, Teater Matt, Jiang Yanwen, Bunting Karen L., Rosen Monica, Shen Hao, Yang Shao Ning, Wang Ling, Ezponda Teresa, et al. , Cancer Cell, 2013 May 13, Volume 23, Issue 5, p.677-92, (2013)
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis., Velichutina, Irina, Shaknovich Rita, Geng Huimin, Johnson Nathalie A., Gascoyne Randy D., Melnick Ari M., and Elemento Olivier , Blood, 2010 Dec 09, Volume 116, Issue 24, p.5247-55, (2010)
The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT., Takahashi, Shinichiro, McConnell Melanie J., Harigae Hideo, Kaku Mitsuo, Sasaki Takeshi, Melnick Ari M., and Licht Jonathan D. , Blood, 2004 Jun 15, Volume 103, Issue 12, p.4650-8, (2004)
Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., Gascoyne, Randy D., Nadel Bertrand, Pasqualucci Laura, Fitzgibbon Jude, Payton Jacqueline E., Melnick Ari, Weigert Oliver, Tarte Karin, Gribben John G., Friedberg Jonathan W., et al. , Hematol Oncol, 2017 Dec, Volume 35, Issue 4, p.397-407, (2017)
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)
General Biomarker Recommendations for Lymphoma., Rimsza, Lisa, Fedoriw Yuri, Staudt Louis M., Melnick Ari, Gascoyne Randy, Crump Michael, Baizer Lawrence, Fu Kai, Hsi Eric, Chan John W. C., et al. , J Natl Cancer Inst, 2016 Dec, Volume 108, Issue 12, (2016)
Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis., Pronier, Elodie, Bowman Robert L., Ahn Jihae, Glass Jacob, Kandoth Cyriac, Merlinsky Tiffany R., Whitfield Justin T., Durham Benjamin H., Gruet Antoine, Somasundara Amritha Varshini H., et al. , Blood, 2018 Sep 20, Volume 132, Issue 12, p.1265-1278, (2018)
Genetic and epigenetic heterogeneity in acute myeloid leukemia., Li, Sheng, Mason Christopher E., and Melnick Ari , Curr Opin Genet Dev, 2016 Feb, Volume 36, p.100-6, (2016)
Genetic and epigenetic inactivation of controls mTORC1 and response to EZH2 inhibition in follicular lymphoma., Oricchio, Elisa, Katanayeva Natalya, Donaldson Maria Christine, Sungalee Stephanie, Pasion Joyce P., Béguelin Wendy, Battistello Elena, Sanghvi Viraj R., Jiang Man, Jiang Yanwen, et al. , Sci Transl Med, 2017 Jun 28, Volume 9, Issue 396, (2017)
Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis., Murphy, Mark W., Sarver Aaron L., Rice Daren, Hatzi Katerina, Ye Kenny, Melnick Ari, Heckert Leslie L., Zarkower David, and Bardwell Vivian J. , Proc Natl Acad Sci U S A, 2010 Jul 27, Volume 107, Issue 30, p.13360-5, (2010)
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., Jiang, Yanwen, T Soong David, Wang Ling, Melnick Ari M., and Elemento Olivier , PLoS One, 2012, Volume 7, Issue 7, p.e40332, (2012)
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias., Figueroa, Maria E., Melnick Ari, and Greally John M. , Methods Mol Biol, 2009, Volume 538, p.395-407, (2009)
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma., Leshchenko, Violetta V., Kuo Pei-Yu, Shaknovich Rita, Yang David T., Gellen Tobias, Petrich Adam, Yu Yiting, Remache Yvonne, Weniger Marc A., Rafiq Sarwish, et al. , Blood, 2010 Aug 19, Volume 116, Issue 7, p.1025-34, (2010)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
Germinal center-derived lymphomas: The darkest side of humoral immunity., Mlynarczyk, Coraline, Fontan Lorena, and Melnick Ari , Immunol Rev, 2019 Mar, Volume 288, Issue 1, p.214-239, (2019)
H1 histones control the epigenetic landscape by local chromatin compaction., Willcockson, Michael A., Healton Sean E., Weiss Cary N., Bartholdy Boris A., Botbol Yair, Mishra Laxmi N., Sidhwani Dhruv S., Wilson Tommy J., Pinto Hugo B., Maron Maxim I., et al. , Nature, 2021 Jan, Volume 589, Issue 7841, p.293-298, (2021)
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia., Kawahara, Masahiro, Pandolfi Ashley, Bartholdy Boris, Barreyro Laura, Will Britta, Roth Michael, Okoye-Okafor Ujunwa C., Todorova Tihomira I., Figueroa Maria E., Melnick Ari, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.194-208, (2012)
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia., Van der Meulen, Joni, Sanghvi Viraj, Mavrakis Konstantinos, Durinck Kaat, Fang Fang, Matthijssens Filip, Rondou Pieter, Rosen Monica, Pieters Tim, Vandenberghe Peter, et al. , Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)
HDAC4 promotes growth of colon cancer cells via repression of p21., Wilson, Andrew J., Byun Do-Sun, Nasser Shannon, Murray Lucas B., Ayyanar Kanyalakshmi, Arango Diego, Figueroa Maria, Melnick Ari, Kao Gary D., Augenlicht Leonard H., et al. , Mol Biol Cell, 2008 Oct, Volume 19, Issue 10, p.4062-75, (2008)
HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for DNA methylation profiling of primary normal and malignant B lymphocytes., Shaknovich, Rita, Figueroa Maria E., and Melnick Ari , Methods Mol Biol, 2010, Volume 632, p.191-201, (2010)
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia., Chung, Stephen S., Kim Eunhee, Park Jae H., Chung Young Rock, Lito Piro, Teruya-Feldstein Julie, Hu Wenhuo, Béguelin Wendy, Monette Sebastien, Duy Cihangir, et al. , Sci Transl Med, 2014 May 28, Volume 6, Issue 238, p.238ra71, (2014)
A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations., Han, Dali, Lu Xingyu, Shih Alan H., Nie Ji, You Qiancheng, Xu Meng Michelle, Melnick Ari M., Levine Ross L., and He Chuan , Mol Cell, 2016 Aug 18, Volume 63, Issue 4, p.711-719, (2016)
High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers., Oda, Mayumi, Glass Jacob L., Thompson Reid F., Mo Yongkai, Olivier Emmanuel N., Figueroa Maria E., Selzer Rebecca R., Richmond Todd A., Zhang Xinmin, Dannenberg Luke, et al. , Nucleic Acids Res, 2009 Jul, Volume 37, Issue 12, p.3829-39, (2009)
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells., Ha, Kyungsoo, Fiskus Warren, Choi Dong Soon, Bhaskara Srividya, Cerchietti Leandro, Devaraj Santhana G. T., Shah Bhavin, Sharma Sunil, Chang Jenny C., Melnick Ari M., et al. , Oncotarget, 2014 Jul 30, Volume 5, Issue 14, p.5637-50, (2014)
Histone deacetylases as therapeutic targets in hematologic malignancies., Melnick, Ari, and Licht Jonathan D. , Curr Opin Hematol, 2002 Jul, Volume 9, Issue 4, p.322-32, (2002)