2013
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.,
De, Subhajyoti, Shaknovich Rita, Riester Markus, Elemento Olivier, Geng Huimin, Kormaksson Matthias, Jiang Yanwen, Woolcock Bruce, Johnson Nathalie, Polo Jose M., et al.
, PLoS Genet, 2013, Volume 9, Issue 1, p.e1003137, (2013)
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint.,
Swaminathan, Srividya, Huang ChuanXin, Geng Huimin, Chen Zhengshan, Harvey Richard, Kang Huining, Ng Carina, Titz Björn, Hurtz Christian, Sadiyah Mohammed Firas, et al.
, Nat Med, 2013 Aug, Volume 19, Issue 8, p.1014-22, (2013)
BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements.,
Lu, Zhengfei, Tsai Albert G., Akasaka Takashi, Ohno Hitoshi, Jiang Yanwen, Melnick Ari M., Greisman Harvey A., and Lieber Michael R.
, Blood, 2013 May 30, Volume 121, Issue 22, p.4551-4, (2013)
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation.,
Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al.
, Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)
DNMT1-interacting RNAs block gene-specific DNA methylation.,
Di Ruscio, Annalisa, Ebralidze Alexander K., Benoukraf Touati, Amabile Giovanni, Goff Loyal A., Terragni Jolyon, Figueroa Maria Eugenia, Pontes Lorena Lobo De Fi, Alberich-Jorda Meritxell, Zhang Pu, et al.
, Nature, 2013 Nov 21, Volume 503, Issue 7476, p.371-6, (2013)
Downregulation of FOXP1 is required during germinal center B-cell function.,
Sagardoy, Ainara, Martinez-Ferrandis Jose I., Roa Sergio, Bunting Karen L., Aznar María Angela, Elemento Olivier, Shaknovich Rita, Fontan Lorena, Fresquet Vicente, Perez-Roger Ignacio, et al.
, Blood, 2013 May 23, Volume 121, Issue 21, p.4311-20, (2013)
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.,
Lin, Pei-Chun, Chiu Ya-Lin, Banerjee Samprit, Park Kyung, Mosquera Juan Miguel, Giannopoulou Eugenia, Alves Pedro, Tewari Ashutosh K., Gerstein Mark B., Beltran Himisha, et al.
, Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1232-44, (2013)
Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents.,
Santini, Valeria, Melnick Ari, Maciejewski Jaroslaw P., Duprez Estelle, Nervi Clara, Cocco Lucio, Ford Kevin G., and Mufti Ghulam
, Crit Rev Oncol Hematol, 2013 Nov, Volume 88, Issue 2, p.231-45, (2013)
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.,
Béguelin, Wendy, Popovic Relja, Teater Matt, Jiang Yanwen, Bunting Karen L., Rosen Monica, Shen Hao, Yang Shao Ning, Wang Ling, Ezponda Teresa, et al.
, Cancer Cell, 2013 May 13, Volume 23, Issue 5, p.677-92, (2013)
A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.,
Hatzi, Katerina, Jiang Yanwen, Huang ChuanXin, Garrett-Bakelman Francine, Gearhart Micah D., Giannopoulou Eugenia G., Zumbo Paul, Kirouac Kevin, Bhaskara Srividya, Polo Jose M., et al.
, Cell Rep, 2013 Aug 15, Volume 4, Issue 3, p.578-88, (2013)
Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes.,
Ruan, Jia, Luo Min, Wang Chunjie, Fan Lei, Yang Shao Ning, Cardenas Mariano, Geng Huimin, Leonard John P., Melnick Ari, Cerchietti Leandro, et al.
, Blood, 2013 Jun 27, Volume 121, Issue 26, p.5192-202, (2013)
Induction of sarcomas by mutant IDH2.,
Lu, Chao, Venneti Sriram, Akalin Altuna, Fang Fang, Ward Patrick S., Dematteo Raymond G., Intlekofer Andrew M., Chen Chong, Ye Jiangbin, Hameed Meera, et al.
, Genes Dev, 2013 Sep 15, Volume 27, Issue 18, p.1986-98, (2013)
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia.,
Figueroa, Maria E., Chen Shann-Ching, Andersson Anna K., Phillips Letha A., Li Yushan, Sotzen Jason, Kundu Mondira, Downing James R., Melnick Ari, and Mullighan Charles G.
, J Clin Invest, 2013 Jul, Volume 123, Issue 7, p.3099-111, (2013)
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms.,
Huang, ChuanXin, Hatzi Katerina, and Melnick Ari
, Nat Immunol, 2013 Apr, Volume 14, Issue 4, p.380-8, (2013)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas.,
Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al.
, Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma.,
Clozel, Thomas, Yang ShaoNing, Elstrom Rebecca L., Tam Wayne, Martin Peter, Kormaksson Matthias, Banerjee Samprit, Vasanthakumar Aparna, Culjkovic Biljana, Scott David W., et al.
, Cancer Discov, 2013 Sep, Volume 3, Issue 9, p.1002-19, (2013)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.,
Nischal, Sangeeta, Bhattacharyya Sanchari, Christopeit Maximilian, Yu Yiting, Zhou Li, Bhagat Tushar D., Sohal Davendra, Will Britta, Mo Yongkai, Suzuki Masako, et al.
, Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.,
Park-Min, Kyung-Hyun, Lee Eun Young, Moskowitz Neal K., Lim Elisha, Lee Sun-Kyeong, Lorenzo Joseph A., Huang ChuanXin, Melnick Ari M., P Purdue Edward, Goldring Steven R., et al.
, J Bone Miner Res, 2013 Jan, Volume 28, Issue 1, p.135-49, (2013)