The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia., Van der Meulen, Joni, Sanghvi Viraj, Mavrakis Konstantinos, Durinck Kaat, Fang Fang, Matthijssens Filip, Rondou Pieter, Rosen Monica, Pieters Tim, Vandenberghe Peter, et al. , Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)

How to add publications - Instructions, Doe, John, and Author Dummy S. , (2015)

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species., Zong, Hongliang, Gozman Alexander, Caldas-Lopes Eloisi, Taldone Tony, Sturgill Eric, Brennan Sarah, Ochiana Stefan O., Gomes-DaGama Erica M., Sen Siddhartha, Rodina Anna, et al. , Cell Rep, 2015 Dec 15, Volume 13, Issue 10, p.2159-73, (2015)

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., Buchner, Maike, Park Eugene, Geng Huimin, Klemm Lars, Flach Johanna, Passegué Emmanuelle, Schjerven Hilde, Melnick Ari, Paietta Elisabeth, Kopanja Dragana, et al. , Nat Commun, 2015 Mar 10, Volume 6, p.6471, (2015)

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Tian, Ye F., Ahn Haelee, Schneider Rebecca S., Yang Shao Ning, Roman-Gonzalez Lidia, Melnick Ari M., Cerchietti Leandro, and Singh Ankur , Biomaterials, 2015 Dec, Volume 73, p.110-9, (2015)

Loss of BAP1 function leads to EZH2-dependent transformation., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2015 Nov, Volume 21, Issue 11, p.1344-9, (2015)

Mechanisms of action of BCL6 during germinal center B cell development., Huang, ChuanXin, and Melnick Ari , Sci China Life Sci, 2015 Dec, Volume 58, Issue 12, p.1226-32, (2015)

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program., Park, Sun-Mi, Gönen Mithat, Vu Ly, Minuesa Gerard, Tivnan Patrick, Barlowe Trevor S., Taggart James, Lu Yuheng, Deering Raquel P., Hacohen Nir, et al. , J Clin Invest, 2015 Mar 02, Volume 125, Issue 3, p.1286-98, (2015)

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al. , J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)

A roadmap for discovery and translation in lymphoma., Weinstock, David M., Dalla-Favera Riccardo, Gascoyne Randy D., Leonard John P., Levy Ronald, Lossos Izidore S., Melnick Ari M., Nowakowski Grzegorz S., Press Oliver W., Savage Kerry J., et al. , Blood, 2015 Mar 26, Volume 125, Issue 13, p.2175-7, (2015)

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia., Geng, Huimin, Hurtz Christian, Lenz Kyle B., Chen Zhengshan, Baumjohann Dirk, Thompson Sarah, Goloviznina Natalya A., Chen Wei-Yi, Huan Jianya, LaTocha Dorian, et al. , Cancer Cell, 2015 Mar 09, Volume 27, Issue 3, p.409-25, (2015)

Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma., Verma, Akanksha, Jiang Yanwen, Du Wei, Fairchild Lauren, Melnick Ari, and Elemento Olivier , Genome Med, 2015 Nov 01, Volume 7, p.110, (2015)

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma., Jiang, Yanwen, Nie Kui, Redmond David, Melnick Ari M., Tam Wayne, and Elemento Olivier , J Vis Exp, 2015 Dec 28, Issue 106, p.e53215, (2015)

VII. Are lymphomas driven by epigenetic lesions?, Boss, Isaac W., and Melnick Ari M. , Hematol Oncol, 2015 Jun, Volume 33 Suppl 1, p.42-5, (2015)

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers., Agirre, Xabier, Castellano Giancarlo, Pascual Marien, Heath Simon, Kulis Marta, Segura Victor, Bergmann Anke, Esteve Anna, Merkel Angelika, Raineri Emanuele, et al. , Genome Res, 2015 Apr, Volume 25, Issue 4, p.478-87, (2015)

Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer., Rodina, Anna, Taldone Tony, Kang Yanlong, Patel Pallav D., Koren John, Yan Pengrong, Gomes Erica M. DaGama, Yang Chenghua, Patel Maulik R., Shrestha Liza, et al. , ACS Chem Biol, 2014 Aug 15, Volume 9, Issue 8, p.1698-705, (2014)

Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)

The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers., Huang, ChuanXin, Gonzalez David G., Cote Christine M., Jiang Yanwen, Hatzi Katerina, Teater Matt, Dai Kezhi, Hla Timothy, Haberman Ann M., and Melnick Ari , Cell Rep, 2014 Sep 11, Volume 8, Issue 5, p.1497-508, (2014)

Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis., Hatzi, Katerina, and Melnick Ari , Trends Mol Med, 2014 Jun, Volume 20, Issue 6, p.343-52, (2014)

Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation., Huang, ChuanXin, Geng Huimin, Boss Isaac, Wang Ling, and Melnick Ari , Blood, 2014 Feb 13, Volume 123, Issue 7, p.1012-20, (2014)

CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer., Kemp, Christopher J., Moore James M., Moser Russell, Bernard Brady, Teater Matt, Smith Leslie E., Rabaia Natalia A., Gurley Kay E., Guinney Justin, Busch Stephanie E., et al. , Cell Rep, 2014 May 22, Volume 7, Issue 4, p.1020-9, (2014)

Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas., Jiang, Yanwen, Redmond David, Nie Kui, Eng Ken W., Clozel Thomas, Martin Peter, Tan Leonard Hc, Melnick Ari M., Tam Wayne, and Elemento Olivier , Genome Biol, 2014 Aug 15, Volume 15, Issue 8, p.432, (2014)

DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia., Rampal, Raajit, Alkalin Altuna, Madzo Jozef, Vasanthakumar Aparna, Pronier Elodie, Patel Jay, Li Yushan, Ahn Jihae, Abdel-Wahab Omar, Shih Alan, et al. , Cell Rep, 2014 Dec 11, Volume 9, Issue 5, p.1841-1855, (2014)