Found 271 results
2013
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes., Bunting, Karen L., and Melnick Ari M. , Curr Opin Immunol, 2013 Jun, Volume 25, Issue 3, p.339-46, (2013)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
An optimized algorithm for detecting and annotating regional differential methylation., Li, Sheng, Garrett-Bakelman Francine E., Akalin Altuna, Zumbo Paul, Levine Ross, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., Melnick Ari, et al. , BMC Bioinformatics, 2013, Volume 14 Suppl 5, Issue Suppl 5, p.S10, (2013)
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex., Vu, Ly P., Perna Fabiana, Wang Lan, Voza Francesca, Figueroa Maria E., Tempst Paul, Erdjument-Bromage Hediye, Gao Rui, Chen Sisi, Paietta Elisabeth, et al. , Cell Rep, 2013 Dec 26, Volume 5, Issue 6, p.1625-38, (2013)
RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction., Wilkinson, Adam C., Ballabio Erica, Geng Huimin, North Phillip, Tapia Marta, Kerry Jon, Biswas Debabrata, Roeder Robert G., C Allis David, Melnick Ari, et al. , Cell Rep, 2013 Jan 31, Volume 3, Issue 1, p.116-27, (2013)
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment., Will, Britta, Vogler Thomas O., Bartholdy Boris, Garrett-Bakelman Francine, Mayer Jillian, Barreyro Laura, Pandolfi Ashley, Todorova Tihomira I., Okoye-Okafor Ujunwa C., Stanley Robert F., et al. , Nat Immunol, 2013 May, Volume 14, Issue 5, p.437-45, (2013)
SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia., Ramezani-Rad, Parham, Geng Huimin, Hurtz Christian, Chan Lai N., Chen Zhengshan, Jumaa Hassan, Melnick Ari, Paietta Elisabeth, Carroll William L., Willman Cheryl L., et al. , Blood, 2013 Jan 03, Volume 121, Issue 1, p.148-55, (2013)
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis., Sun, Xiao-Jian, Wang Zhanxin, Wang Lan, Jiang Yanwen, Kost Nils, T Soong David, Chen Wei-Yi, Tang Zhanyun, Nakadai Tomoyoshi, Elemento Olivier, et al. , Nature, 2013 Aug 01, Volume 500, Issue 7460, p.93-7, (2013)
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly., Qiao, Qi, Yang Chenghua, Zheng Chao, Fontan Lorena, David Liron, Yu Xiong, Bracken Clay, Rosen Monica, Melnick Ari, Egelman Edward H., et al. , Mol Cell, 2013 Sep 26, Volume 51, Issue 6, p.766-79, (2013)
Targeting BCL6 in diffuse large B-cell lymphoma: what does this mean for the future treatment?, Cerchietti, Leandro, and Melnick Ari , Expert Rev Hematol, 2013 Aug, Volume 6, Issue 4, p.343-5, (2013)
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies., Nayar, Utthara, Lu Pin, Goldstein Rebecca L., Vider Jelena, Ballon Gianna, Rodina Anna, Taldone Tony, Erdjument-Bromage Hediye, Chomet Max, Blasberg Ronald, et al. , Blood, 2013 Oct 17, Volume 122, Issue 16, p.2837-47, (2013)
2014
Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer., Rodina, Anna, Taldone Tony, Kang Yanlong, Patel Pallav D., Koren John, Yan Pengrong, Gomes Erica M. DaGama, Yang Chenghua, Patel Maulik R., Shrestha Liza, et al. , ACS Chem Biol, 2014 Aug 15, Volume 9, Issue 8, p.1698-705, (2014)
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)
The BCL6 RD2 domain governs commitment of activated B cells to form germinal centers., Huang, ChuanXin, Gonzalez David G., Cote Christine M., Jiang Yanwen, Hatzi Katerina, Teater Matt, Dai Kezhi, Hla Timothy, Haberman Ann M., and Melnick Ari , Cell Rep, 2014 Sep 11, Volume 8, Issue 5, p.1497-508, (2014)
Breaking bad in the germinal center: how deregulation of BCL6 contributes to lymphomagenesis., Hatzi, Katerina, and Melnick Ari , Trends Mol Med, 2014 Jun, Volume 20, Issue 6, p.343-52, (2014)
Cooperative transcriptional repression by BCL6 and BACH2 in germinal center B-cell differentiation., Huang, ChuanXin, Geng Huimin, Boss Isaac, Wang Ling, and Melnick Ari , Blood, 2014 Feb 13, Volume 123, Issue 7, p.1012-20, (2014)
CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer., Kemp, Christopher J., Moore James M., Moser Russell, Bernard Brady, Teater Matt, Smith Leslie E., Rabaia Natalia A., Gurley Kay E., Guinney Justin, Busch Stephanie E., et al. , Cell Rep, 2014 May 22, Volume 7, Issue 4, p.1020-9, (2014)
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas., Jiang, Yanwen, Redmond David, Nie Kui, Eng Ken W., Clozel Thomas, Martin Peter, Tan Leonard Hc, Melnick Ari M., Tam Wayne, and Elemento Olivier , Genome Biol, 2014 Aug 15, Volume 15, Issue 8, p.432, (2014)
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia., Rampal, Raajit, Alkalin Altuna, Madzo Jozef, Vasanthakumar Aparna, Pronier Elodie, Patel Jay, Li Yushan, Ahn Jihae, Abdel-Wahab Omar, Shih Alan, et al. , Cell Rep, 2014 Dec 11, Volume 9, Issue 5, p.1841-1855, (2014)
Dynamic evolution of clonal epialleles revealed by methclone., Li, Sheng, Garrett-Bakelman Francine, Perl Alexander E., Luger Selina M., Zhang Chao, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., M Ross Elizabeth, et al. , Genome Biol, 2014 Sep 27, Volume 15, Issue 9, p.472, (2014)
Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia., Chung, Stephen S., Kim Eunhee, Park Jae H., Chung Young Rock, Lito Piro, Teruya-Feldstein Julie, Hu Wenhuo, Béguelin Wendy, Monette Sebastien, Duy Cihangir, et al. , Sci Transl Med, 2014 May 28, Volume 6, Issue 238, p.238ra71, (2014)
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells., Ha, Kyungsoo, Fiskus Warren, Choi Dong Soon, Bhaskara Srividya, Cerchietti Leandro, Devaraj Santhana G. T., Shah Bhavin, Sharma Sunil, Chang Jenny C., Melnick Ari M., et al. , Oncotarget, 2014 Jul 30, Volume 5, Issue 14, p.5637-50, (2014)
HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia., Bartholdy, Boris, Christopeit Maximilian, Will Britta, Mo Yongkai, Barreyro Laura, Yu Yiting, Bhagat Tushar D., Okoye-Okafor Ujunwa C., Todorova Tihomira I., Greally John M., et al. , J Clin Invest, 2014 Mar, Volume 124, Issue 3, p.1158-67, (2014)
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)
Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications., Patel, Ravi Ghanshyam, Purwada Alberto, Cerchietti Leandro, Inghirami Giorgio, Melnick Ari, Gaharwar Akhilesh K., and Singh Ankur , Cell Mol Bioeng, 2014 Sep 01, Volume 7, Issue 3, p.394-408, (2014)