Dynamic evolution of clonal epialleles revealed by methclone., Li, Sheng, Garrett-Bakelman Francine, Perl Alexander E., Luger Selina M., Zhang Chao, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., M Ross Elizabeth, et al. , Genome Biol, 2014 Sep 27, Volume 15, Issue 9, p.472, (2014)

Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia., Chung, Stephen S., Kim Eunhee, Park Jae H., Chung Young Rock, Lito Piro, Teruya-Feldstein Julie, Hu Wenhuo, Béguelin Wendy, Monette Sebastien, Duy Cihangir, et al. , Sci Transl Med, 2014 May 28, Volume 6, Issue 238, p.238ra71, (2014)

Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells., Ha, Kyungsoo, Fiskus Warren, Choi Dong Soon, Bhaskara Srividya, Cerchietti Leandro, Devaraj Santhana G. T., Shah Bhavin, Sharma Sunil, Chang Jenny C., Melnick Ari M., et al. , Oncotarget, 2014 Jul 30, Volume 5, Issue 14, p.5637-50, (2014)

HSC commitment-associated epigenetic signature is prognostic in acute myeloid leukemia., Bartholdy, Boris, Christopeit Maximilian, Will Britta, Mo Yongkai, Barreyro Laura, Yu Yiting, Bhagat Tushar D., Okoye-Okafor Ujunwa C., Todorova Tihomira I., Greally John M., et al. , J Clin Invest, 2014 Mar, Volume 124, Issue 3, p.1158-67, (2014)

Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia., Masouleh, Behzad Kharabi, Geng Huimin, Hurtz Christian, Chan Lai N., Logan Aaron C., Chang Mi Sook, Huang ChuanXin, Swaminathan Srividya, Sun Haibo, Paietta Elisabeth, et al. , Proc Natl Acad Sci U S A, 2014 May 27, Volume 111, Issue 21, p.E2219-28, (2014)

Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications., Patel, Ravi Ghanshyam, Purwada Alberto, Cerchietti Leandro, Inghirami Giorgio, Melnick Ari, Gaharwar Akhilesh K., and Singh Ankur , Cell Mol Bioeng, 2014 Sep 01, Volume 7, Issue 3, p.394-408, (2014)

Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905., Prebet, Thomas, Sun Zhuoxin, Figueroa Maria E., Ketterling Rhett, Melnick Ari, Greenberg Peter L., Herman James, Juckett Mark, Smith Mitchell R., Malick Lisa, et al. , J Clin Oncol, 2014 Apr 20, Volume 32, Issue 12, p.1242-8, (2014)

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma., Green, Michael R., Vicente-Dueñas Carolina, Romero-Camarero Isabel, Liu Chih Long, Dai Bo, González-Herrero Inés, García-Ramírez Idoia, Alonso-Escudero Esther, Iqbal Javeed, Chan Wing C., et al. , Nat Commun, 2014 Jun 02, Volume 5, p.3904, (2014)

Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling., Taskesen, Erdogan, Havermans Marije, van Lom Kirsten, Sanders Mathijs A., van Norden Yvette, Bindels Eric, Hoogenboezem Remco, Reinders Marcel J. T., Figueroa Maria E., Valk Peter J. M., et al. , Blood, 2014 May 22, Volume 123, Issue 21, p.3327-35, (2014)

Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes., Chambwe, Nyasha, Kormaksson Matthias, Geng Huimin, De Subhajyoti, Michor Franziska, Johnson Nathalie A., Morin Ryan D., Scott David W., Godley Lucy A., Gascoyne Randy D., et al. , Blood, 2014 Mar 13, Volume 123, Issue 11, p.1699-708, (2014)

Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity., De, Subhajyoti, Shaknovich Rita, Riester Markus, Elemento Olivier, Geng Huimin, Kormaksson Matthias, Jiang Yanwen, Woolcock Bruce, Johnson Nathalie, Polo Jose M., et al. , PLoS Genet, 2013, Volume 9, Issue 1, p.e1003137, (2013)

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint., Swaminathan, Srividya, Huang ChuanXin, Geng Huimin, Chen Zhengshan, Harvey Richard, Kang Huining, Ng Carina, Titz Björn, Hurtz Christian, Sadiyah Mohammed Firas, et al. , Nat Med, 2013 Aug, Volume 19, Issue 8, p.1014-22, (2013)

BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements., Lu, Zhengfei, Tsai Albert G., Akasaka Takashi, Ohno Hitoshi, Jiang Yanwen, Melnick Ari M., Greisman Harvey A., and Lieber Michael R. , Blood, 2013 May 30, Volume 121, Issue 22, p.4551-4, (2013)

Differentiation therapy for IDH1/2 mutant malignancies., Garrett-Bakelman, Francine E., and Melnick Ari M. , Cell Res, 2013 Aug, Volume 23, Issue 8, p.975-7, (2013)

Discovering what makes STAT signaling TYK in T-ALL., Fontan, Lorena, and Melnick Ari , Cancer Discov, 2013 May, Volume 3, Issue 5, p.494-6, (2013)

DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation., Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al. , Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)

DNMT1-interacting RNAs block gene-specific DNA methylation., Di Ruscio, Annalisa, Ebralidze Alexander K., Benoukraf Touati, Amabile Giovanni, Goff Loyal A., Terragni Jolyon, Figueroa Maria Eugenia, Pontes Lorena Lobo De Fi, Alberich-Jorda Meritxell, Zhang Pu, et al. , Nature, 2013 Nov 21, Volume 503, Issue 7476, p.371-6, (2013)

Downregulation of FOXP1 is required during germinal center B-cell function., Sagardoy, Ainara, Martinez-Ferrandis Jose I., Roa Sergio, Bunting Karen L., Aznar María Angela, Elemento Olivier, Shaknovich Rita, Fontan Lorena, Fresquet Vicente, Perez-Roger Ignacio, et al. , Blood, 2013 May 23, Volume 121, Issue 21, p.4311-20, (2013)

Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression., Lin, Pei-Chun, Chiu Ya-Lin, Banerjee Samprit, Park Kyung, Mosquera Juan Miguel, Giannopoulou Eugenia, Alves Pedro, Tewari Ashutosh K., Gerstein Mark B., Beltran Himisha, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1232-44, (2013)

Epigenetics in focus: pathogenesis of myelodysplastic syndromes and the role of hypomethylating agents., Santini, Valeria, Melnick Ari, Maciejewski Jaroslaw P., Duprez Estelle, Nervi Clara, Cocco Lucio, Ford Kevin G., and Mufti Ghulam , Crit Rev Oncol Hematol, 2013 Nov, Volume 88, Issue 2, p.231-45, (2013)

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation., Béguelin, Wendy, Popovic Relja, Teater Matt, Jiang Yanwen, Bunting Karen L., Rosen Monica, Shen Hao, Yang Shao Ning, Wang Ling, Ezponda Teresa, et al. , Cancer Cell, 2013 May 13, Volume 23, Issue 5, p.677-92, (2013)

A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters., Hatzi, Katerina, Jiang Yanwen, Huang ChuanXin, Garrett-Bakelman Francine, Gearhart Micah D., Giannopoulou Eugenia G., Zumbo Paul, Kirouac Kevin, Bhaskara Srividya, Polo Jose M., et al. , Cell Rep, 2013 Aug 15, Volume 4, Issue 3, p.578-88, (2013)

Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes., Ruan, Jia, Luo Min, Wang Chunjie, Fan Lei, Yang Shao Ning, Cardenas Mariano, Geng Huimin, Leonard John P., Melnick Ari, Cerchietti Leandro, et al. , Blood, 2013 Jun 27, Volume 121, Issue 26, p.5192-202, (2013)

Induction of sarcomas by mutant IDH2., Lu, Chao, Venneti Sriram, Akalin Altuna, Fang Fang, Ward Patrick S., Dematteo Raymond G., Intlekofer Andrew M., Chen Chong, Ye Jiangbin, Hameed Meera, et al. , Genes Dev, 2013 Sep 15, Volume 27, Issue 18, p.1986-98, (2013)

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia., Figueroa, Maria E., Chen Shann-Ching, Andersson Anna K., Phillips Letha A., Li Yushan, Sotzen Jason, Kundu Mondira, Downing James R., Melnick Ari, and Mullighan Charles G. , J Clin Invest, 2013 Jul, Volume 123, Issue 7, p.3099-111, (2013)