Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905., Prebet, Thomas, Sun Zhuoxin, Figueroa Maria E., Ketterling Rhett, Melnick Ari, Greenberg Peter L., Herman James, Juckett Mark, Smith Mitchell R., Malick Lisa, et al. , J Clin Oncol, 2014 Apr 20, Volume 32, Issue 12, p.1242-8, (2014)

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma., Green, Michael R., Vicente-Dueñas Carolina, Romero-Camarero Isabel, Liu Chih Long, Dai Bo, González-Herrero Inés, García-Ramírez Idoia, Alonso-Escudero Esther, Iqbal Javeed, Chan Wing C., et al. , Nat Commun, 2014 Jun 02, Volume 5, p.3904, (2014)

Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling., Taskesen, Erdogan, Havermans Marije, van Lom Kirsten, Sanders Mathijs A., van Norden Yvette, Bindels Eric, Hoogenboezem Remco, Reinders Marcel J. T., Figueroa Maria E., Valk Peter J. M., et al. , Blood, 2014 May 22, Volume 123, Issue 21, p.3327-35, (2014)

Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes., Chambwe, Nyasha, Kormaksson Matthias, Geng Huimin, De Subhajyoti, Michor Franziska, Johnson Nathalie A., Morin Ryan D., Scott David W., Godley Lucy A., Gascoyne Randy D., et al. , Blood, 2014 Mar 13, Volume 123, Issue 11, p.1699-708, (2014)

BCL6 orchestrates Tfh cell differentiation via multiple distinct mechanisms., Hatzi, Katerina, J Nance Philip, Kroenke Mark A., Bothwell Marcella, Haddad Elias K., Melnick Ari, and Crotty Shane , J Exp Med, 2015 Apr 06, Volume 212, Issue 4, p.539-53, (2015)

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID., Dominguez, Pilar M., Teater Matt, Chambwe Nyasha, Kormaksson Matthias, Redmond David, Ishii Jennifer, Vuong Bao, Chaudhuri Jayanta, Melnick Ari, Vasanthakumar Aparna, et al. , Cell Rep, 2015 Sep 29, Volume 12, Issue 12, p.2086-98, (2015)

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis., Viny, Aaron D., Ott Christopher J., Spitzer Barbara, Rivas Martín, Meydan Cem, Papalexi Efthymia, Yelin Dana, Shank Kaitlyn, Reyes Jaime, Chiu April, et al. , J Exp Med, 2015 Oct 19, Volume 212, Issue 11, p.1819-32, (2015)

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., Noh, Kyung-Min, Wang Haibo, Kim Hyunjae R., Wenderski Wendy, Fang Fang, Li Charles H., Dewell Scott, Hughes Stephen H., Melnick Ari M., Patel Dinshaw J., et al. , Mol Cell, 2015 Jul 02, Volume 59, Issue 1, p.89-103, (2015)

Enhanced reduced representation bisulfite sequencing for assessment of DNA methylation at base pair resolution., Garrett-Bakelman, Francine E., Sheridan Caroline K., Kacmarczyk Thadeous J., Ishii Jennifer, Betel Doron, Alonso Alicia, Mason Christopher E., Figueroa Maria E., and Melnick Ari M. , J Vis Exp, 2015 Feb 24, Issue 96, p.e52246, (2015)

The epigenetic basis of diffuse large B-cell lymphoma., Jiang, Yanwen, and Melnick Ari , Semin Hematol, 2015 Apr, Volume 52, Issue 2, p.86-96, (2015)

Epigenomic evolution in diffuse large B-cell lymphomas., Pan, Heng, Jiang Yanwen, Boi Michela, Tabbò Fabrizio, Redmond David, Nie Kui, Ladetto Marco, Chiappella Annalisa, Cerchietti Leandro, Shaknovich Rita, et al. , Nat Commun, 2015 Apr 20, Volume 6, p.6921, (2015)

Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia., Shojaee, Seyedmehdi, Caeser Rebecca, Buchner Maike, Park Eugene, Swaminathan Srividya, Hurtz Christian, Geng Huimin, Chan Lai N., Klemm Lars, Hofmann Wolf-Karsten, et al. , Cancer Cell, 2015 Jul 13, Volume 28, Issue 1, p.114-28, (2015)

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia., Van der Meulen, Joni, Sanghvi Viraj, Mavrakis Konstantinos, Durinck Kaat, Fang Fang, Matthijssens Filip, Rondou Pieter, Rosen Monica, Pieters Tim, Vandenberghe Peter, et al. , Blood, 2015 Jan 01, Volume 125, Issue 1, p.13-21, (2015)

The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development., Ortega-Molina, Ana, Boss Isaac W., Canela Andres, Pan Heng, Jiang Yanwen, Zhao Chunying, Jiang Man, Hu Deqing, Agirre Xabier, Niesvizky Itamar, et al. , Nat Med, 2015 Oct, Volume 21, Issue 10, p.1199-208, (2015)

How to add publications - Instructions, Doe, John, and Author Dummy S. , (2015)

A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species., Zong, Hongliang, Gozman Alexander, Caldas-Lopes Eloisi, Taldone Tony, Sturgill Eric, Brennan Sarah, Ochiana Stefan O., Gomes-DaGama Erica M., Sen Siddhartha, Rodina Anna, et al. , Cell Rep, 2015 Dec 15, Volume 13, Issue 10, p.2159-73, (2015)

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia., Buchner, Maike, Park Eugene, Geng Huimin, Klemm Lars, Flach Johanna, Passegué Emmanuelle, Schjerven Hilde, Melnick Ari, Paietta Elisabeth, Kopanja Dragana, et al. , Nat Commun, 2015 Mar 10, Volume 6, p.6471, (2015)

Integrin-specific hydrogels as adaptable tumor organoids for malignant B and T cells., Tian, Ye F., Ahn Haelee, Schneider Rebecca S., Yang Shao Ning, Roman-Gonzalez Lidia, Melnick Ari M., Cerchietti Leandro, and Singh Ankur , Biomaterials, 2015 Dec, Volume 73, p.110-9, (2015)

Loss of BAP1 function leads to EZH2-dependent transformation., LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2015 Nov, Volume 21, Issue 11, p.1344-9, (2015)

Mechanisms of action of BCL6 during germinal center B cell development., Huang, ChuanXin, and Melnick Ari , Sci China Life Sci, 2015 Dec, Volume 58, Issue 12, p.1226-32, (2015)

Musashi2 sustains the mixed-lineage leukemia-driven stem cell regulatory program., Park, Sun-Mi, Gönen Mithat, Vu Ly, Minuesa Gerard, Tivnan Patrick, Barlowe Trevor S., Taggart James, Lu Yuheng, Deering Raquel P., Hacohen Nir, et al. , J Clin Invest, 2015 Mar 02, Volume 125, Issue 3, p.1286-98, (2015)

Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia., Shih, Alan H., Jiang Yanwen, Meydan Cem, Shank Kaitlyn, Pandey Suveg, Barreyro Laura, Antony-Debre Ileana, Viale Agnes, Socci Nicholas, Sun Yongming, et al. , Cancer Cell, 2015 Apr 13, Volume 27, Issue 4, p.502-15, (2015)

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma., Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al. , J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)

A roadmap for discovery and translation in lymphoma., Weinstock, David M., Dalla-Favera Riccardo, Gascoyne Randy D., Leonard John P., Levy Ronald, Lossos Izidore S., Melnick Ari M., Nowakowski Grzegorz S., Press Oliver W., Savage Kerry J., et al. , Blood, 2015 Mar 26, Volume 125, Issue 13, p.2175-7, (2015)

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia., Geng, Huimin, Hurtz Christian, Lenz Kyle B., Chen Zhengshan, Baumjohann Dirk, Thompson Sarah, Goloviznina Natalya A., Chen Wei-Yi, Huan Jianya, LaTocha Dorian, et al. , Cancer Cell, 2015 Mar 09, Volume 27, Issue 3, p.409-25, (2015)