Found 271 results
2013
Lineage-specific functions of Bcl-6 in immunity and inflammation are mediated by distinct biochemical mechanisms., Huang, ChuanXin, Hatzi Katerina, and Melnick Ari , Nat Immunol, 2013 Apr, Volume 14, Issue 4, p.380-8, (2013)
LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas., Bertolo, Cristina, Roa Sergio, Sagardoy Ainara, Mena-Varas Maria, Robles Eloy F., Martinez-Ferrandis Jose I., Sagaert Xavier, Tousseyn Thomas, Orta Alberto, Lossos Izidore S., et al. , Br J Haematol, 2013 Sep, Volume 162, Issue 5, p.621-30, (2013)
Mechanism-based epigenetic chemosensitization therapy of diffuse large B-cell lymphoma., Clozel, Thomas, Yang ShaoNing, Elstrom Rebecca L., Tam Wayne, Martin Peter, Kormaksson Matthias, Banerjee Samprit, Vasanthakumar Aparna, Culjkovic Biljana, Scott David W., et al. , Cancer Discov, 2013 Sep, Volume 3, Issue 9, p.1002-19, (2013)
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms., Nischal, Sangeeta, Bhattacharyya Sanchari, Christopeit Maximilian, Yu Yiting, Zhou Li, Bhagat Tushar D., Sohal Davendra, Will Britta, Mo Yongkai, Suzuki Masako, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1076-85, (2013)
Molecular pathways: targeting MALT1 paracaspase activity in lymphoma., Fontan, Lorena, and Melnick Ari , Clin Cancer Res, 2013 Dec 15, Volume 19, Issue 24, p.6662-8, (2013)
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling., Park-Min, Kyung-Hyun, Lee Eun Young, Moskowitz Neal K., Lim Elisha, Lee Sun-Kyeong, Lorenzo Joseph A., Huang ChuanXin, Melnick Ari M., P Purdue Edward, Goldring Steven R., et al. , J Bone Miner Res, 2013 Jan, Volume 28, Issue 1, p.135-49, (2013)
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes., Bunting, Karen L., and Melnick Ari M. , Curr Opin Immunol, 2013 Jun, Volume 25, Issue 3, p.339-46, (2013)
Notch activation inhibits AML growth and survival: a potential therapeutic approach., Kannan, Sankaranarayanan, Sutphin Robert M., Hall Mandy G., Golfman Leonard S., Fang Wendy, Nolo Riitta M., Akers Lauren J., Hammitt Richard A., McMurray John S., Kornblau Steven M., et al. , J Exp Med, 2013 Feb 11, Volume 210, Issue 2, p.321-37, (2013)
An optimized algorithm for detecting and annotating regional differential methylation., Li, Sheng, Garrett-Bakelman Francine E., Akalin Altuna, Zumbo Paul, Levine Ross, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., Melnick Ari, et al. , BMC Bioinformatics, 2013, Volume 14 Suppl 5, Issue Suppl 5, p.S10, (2013)
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex., Vu, Ly P., Perna Fabiana, Wang Lan, Voza Francesca, Figueroa Maria E., Tempst Paul, Erdjument-Bromage Hediye, Gao Rui, Chen Sisi, Paietta Elisabeth, et al. , Cell Rep, 2013 Dec 26, Volume 5, Issue 6, p.1625-38, (2013)
RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction., Wilkinson, Adam C., Ballabio Erica, Geng Huimin, North Phillip, Tapia Marta, Kerry Jon, Biswas Debabrata, Roeder Robert G., C Allis David, Melnick Ari, et al. , Cell Rep, 2013 Jan 31, Volume 3, Issue 1, p.116-27, (2013)
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment., Will, Britta, Vogler Thomas O., Bartholdy Boris, Garrett-Bakelman Francine, Mayer Jillian, Barreyro Laura, Pandolfi Ashley, Todorova Tihomira I., Okoye-Okafor Ujunwa C., Stanley Robert F., et al. , Nat Immunol, 2013 May, Volume 14, Issue 5, p.437-45, (2013)
SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia., Ramezani-Rad, Parham, Geng Huimin, Hurtz Christian, Chan Lai N., Chen Zhengshan, Jumaa Hassan, Melnick Ari, Paietta Elisabeth, Carroll William L., Willman Cheryl L., et al. , Blood, 2013 Jan 03, Volume 121, Issue 1, p.148-55, (2013)
A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis., Sun, Xiao-Jian, Wang Zhanxin, Wang Lan, Jiang Yanwen, Kost Nils, T Soong David, Chen Wei-Yi, Tang Zhanyun, Nakadai Tomoyoshi, Elemento Olivier, et al. , Nature, 2013 Aug 01, Volume 500, Issue 7460, p.93-7, (2013)
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly., Qiao, Qi, Yang Chenghua, Zheng Chao, Fontan Lorena, David Liron, Yu Xiong, Bracken Clay, Rosen Monica, Melnick Ari, Egelman Edward H., et al. , Mol Cell, 2013 Sep 26, Volume 51, Issue 6, p.766-79, (2013)
Targeting BCL6 in diffuse large B-cell lymphoma: what does this mean for the future treatment?, Cerchietti, Leandro, and Melnick Ari , Expert Rev Hematol, 2013 Aug, Volume 6, Issue 4, p.343-5, (2013)
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies., Nayar, Utthara, Lu Pin, Goldstein Rebecca L., Vider Jelena, Ballon Gianna, Rodina Anna, Taldone Tony, Erdjument-Bromage Hediye, Chomet Max, Blasberg Ronald, et al. , Blood, 2013 Oct 17, Volume 122, Issue 16, p.2837-47, (2013)
2012
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression., Abdel-Wahab, Omar, Adli Mazhar, LaFave Lindsay M., Gao Jie, Hricik Todd, Shih Alan H., Pandey Suveg, Patel Jay P., Chung Young Rock, Koche Richard, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.180-93, (2012)
Base-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in acute myeloid leukemia., Akalin, Altuna, Garrett-Bakelman Francine E., Kormaksson Matthias, Busuttil Jennifer, Zhang Lu, Khrebtukova Irina, Milne Thomas A., Huang Yongsheng, Biswas Debabrata, Hess Jay L., et al. , PLoS Genet, 2012, Volume 8, Issue 6, p.e1002781, (2012)
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis., Barish, Grant D., Yu Ruth T., Karunasiri Malith S., Becerra Diana, Kim Jason, Tseng Tiffany W., Tai Li-Jung, Leblanc Matthias, Diehl Cody, Cerchietti Leandro, et al. , Cell Metab, 2012 Apr 04, Volume 15, Issue 4, p.554-62, (2012)
CD25 expression status improves prognostic risk classification in AML independent of established biomarkers: ECOG phase 3 trial, E1900., Gönen, Mithat, Sun Zhuoxin, Figueroa Maria E., Patel Jay P., Abdel-Wahab Omar, Racevskis Janis, Ketterling Rhett P., Fernandez Hugo, Rowe Jacob M., Tallman Martin S., et al. , Blood, 2012 Sep 13, Volume 120, Issue 11, p.2297-306, (2012)
C/EBPγ deregulation results in differentiation arrest in acute myeloid leukemia., Alberich-Jorda, Meritxell, Wouters Bas, Balastik Martin, Shapiro-Koss Clara, Zhang Hong, Di Ruscio Annalisa, Radomska Hanna S., Ebralidze Alexander K., Amabile Giovanni, Ye Min, et al. , J Clin Invest, 2012 Dec, Volume 122, Issue 12, p.4490-504, (2012)
Epigenetic therapy leaps ahead with specific targeting of EZH2., Melnick, Ari , Cancer Cell, 2012 Nov 13, Volume 22, Issue 5, p.569-70, (2012)
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma., Jiang, Yanwen, T Soong David, Wang Ling, Melnick Ari M., and Elemento Olivier , PLoS One, 2012, Volume 7, Issue 7, p.e40332, (2012)
H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia., Kawahara, Masahiro, Pandolfi Ashley, Bartholdy Boris, Barreyro Laura, Will Britta, Roth Michael, Okoye-Okafor Ujunwa C., Todorova Tihomira I., Figueroa Maria E., Melnick Ari, et al. , Cancer Cell, 2012 Aug 14, Volume 22, Issue 2, p.194-208, (2012)