2016
A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia.,
Luskin, Marlise R., Gimotty Phyllis A., Smith Catherine, Loren Alison W., Figueroa Maria E., Harrison Jenna, Sun Zhuoxin, Tallman Martin S., Paietta Elisabeth M., Litzow Mark R., et al.
, JCI Insight, 2016 Jun 16, Volume 1, Issue 9, (2016)
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas.,
Culjkovic-Kraljacic, Biljana, Fernando Tharu M., Marullo Rossella, Calvo-Vidal Nieves, Verma Akanksha, Yang ShaoNing, Tabbò Fabrizio, Gaudiano Marcello, Zahreddine Hiba, Goldstein Rebecca L., et al.
, Blood, 2016 Feb 18, Volume 127, Issue 7, p.858-68, (2016)
Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.,
Chen, Zhengshan, Shojaee Seyedmehdi, Buchner Maike, Geng Huimin, Lee Jae Woong, Klemm Lars, Titz Björn, Graeber Thomas G., Park Eugene, Tan Ying Xim, et al.
, Nature, 2016 Jun 02, Volume 534, Issue 7605, p.138, (2016)
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.,
Li, Sheng, Garrett-Bakelman Francine E., Chung Stephen S., Sanders Mathijs A., Hricik Todd, Rapaport Franck, Patel Jay, Dillon Richard, Vijay Priyanka, Brown Anna L., et al.
, Nat Med, 2016 Jul, Volume 22, Issue 7, p.792-9, (2016)
DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.,
Meyer, Sara E., Qin Tingting, Muench David E., Masuda Kohei, Venkatasubramanian Meenakshi, Orr Emily, Suarez Lauren, Gore Steven D., Delwel Ruud, Paietta Elisabeth, et al.
, Cancer Discov, 2016 May, Volume 6, Issue 5, p.501-15, (2016)
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.,
Guryanova, Olga A., Shank Kaitlyn, Spitzer Barbara, Luciani Luisa, Koche Richard P., Garrett-Bakelman Francine E., Ganzel Chezi, Durham Benjamin H., Mohanty Abhinita, Hoermann Gregor, et al.
, Nat Med, 2016 Dec, Volume 22, Issue 12, p.1488-1495, (2016)
The epichaperome is an integrated chaperome network that facilitates tumour survival.,
Rodina, Anna, Wang Tai, Yan Pengrong, Gomes Erica DaGama, Dunphy Mark P. S., Pillarsetty Nagavarakishore, Koren John, Gerecitano John F., Taldone Tony, Zong Hongliang, et al.
, Nature, 2016 Oct 20, Volume 538, Issue 7625, p.397-401, (2016)
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.,
Béguelin, Wendy, Teater Matt, Gearhart Micah D., Fernández María Teresa Cal, Goldstein Rebecca L., Cardenas Mariano G., Hatzi Katerina, Rosen Monica, Shen Hao, Corcoran Connie M., et al.
, Cancer Cell, 2016 Aug 08, Volume 30, Issue 2, p.197-213, (2016)
General Biomarker Recommendations for Lymphoma.,
Rimsza, Lisa, Fedoriw Yuri, Staudt Louis M., Melnick Ari, Gascoyne Randy, Crump Michael, Baizer Lawrence, Fu Kai, Hsi Eric, Chan John W. C., et al.
, J Natl Cancer Inst, 2016 Dec, Volume 108, Issue 12, (2016)
A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.,
Han, Dali, Lu Xingyu, Shih Alan H., Nie Ji, You Qiancheng, Xu Meng Michelle, Melnick Ari M., Levine Ross L., and He Chuan
, Mol Cell, 2016 Aug 18, Volume 63, Issue 4, p.711-719, (2016)
Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.,
Robles, Eloy F., Mena-Varas Maria, Barrio Laura, Merino-Cortes Sara V., Balogh Péter, Du Ming-Qing, Akasaka Takashi, Parker Anton, Roa Sergio, Panizo Carlos, et al.
, Nat Commun, 2016 Jun 14, Volume 7, p.11889, (2016)
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas.,
Bayliss, Jill, Mukherjee Piali, Lu Chao, Jain Siddhant U., Chung Chan, Martinez Daniel, Sabari Benjamin, Margol Ashley S., Panwalkar Pooja, Parolia Abhijit, et al.
, Sci Transl Med, 2016 Nov 23, Volume 8, Issue 366, p.366ra161, (2016)
The many layers of epigenetic dysfunction in B-cell lymphomas.,
Jiang, Yanwen, Dominguez Pilar M., and Melnick Ari M.
, Curr Opin Hematol, 2016 Jul, Volume 23, Issue 4, p.377-84, (2016)
miR-181a negatively regulates NF-κB signaling and affects activated B-cell-like diffuse large B-cell lymphoma pathogenesis.,
Kozloski, Goldi A., Jiang Xiaoyu, Bhatt Shruti, Ruiz Jose, Vega Francisco, Shaknovich Rita, Melnick Ari, and Lossos Izidore S.
, Blood, 2016 Jun 09, Volume 127, Issue 23, p.2856-66, (2016)
Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region.,
Bunting, Karen L., T Soong David, Singh Rajat, Jiang Yanwen, Béguelin Wendy, Poloway David W., Swed Brandon L., Hatzi Katerina, Reisacher William, Teater Matt, et al.
, Immunity, 2016 Sep 20, Volume 45, Issue 3, p.497-512, (2016)
Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.,
Garrett-Bakelman, Francine E., and Melnick Ari M.
, Epigenomics, 2016 Jul, Volume 8, Issue 7, p.945-57, (2016)
Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma.,
Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al.
, Blood, 2016 Jul 07, Volume 128, Issue 1, p.82-92, (2016)
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells.,
Shojaee, Seyedmehdi, Chan Lai N., Buchner Maike, Cazzaniga Valeria, Cosgun Kadriye Nehir, Geng Huimin, Qiu Yi Hua, von Minden Marcus Dühren, Ernst Thomas, Hochhaus Andreas, et al.
, Nat Med, 2016 Apr, Volume 22, Issue 4, p.379-87, (2016)
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.,
Cardenas, Mariano G., Yu Wenbo, Béguelin Wendy, Teater Matthew R., Geng Huimin, Goldstein Rebecca L., Oswald Erin, Hatzi Katerina, Yang Shao-Ning, Cohen Joanna, et al.
, J Clin Invest, 2016 Sep 01, Volume 126, Issue 9, p.3351-62, (2016)
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".,
LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al.
, Nat Med, 2016 Jun 07, Volume 22, Issue 6, p.578-9, (2016)
