Found 271 results
2012
Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma., Cubedo, Elena, Gentles Andrew J., Huang ChuanXin, Natkunam Yasodha, Bhatt Shruti, Lu Xiaoqing, Jiang Xiaoyu, Romero-Camarero Isabel, Freud Aharon, Zhao Shuchun, et al. , Blood, 2012 Jun 07, Volume 119, Issue 23, p.5478-91, (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics., Sasaki, Masato, Knobbe Christiane B., Munger Joshua C., Lind Evan F., Brenner Dirk, Brüstle Anne, Harris Isaac S., Holmes Roxanne, Wakeham Andrew, Haight Jillian, et al. , Nature, 2012 Aug 30, Volume 488, Issue 7413, p.656-9, (2012)
Incidence and clinical implications of ATM aberrations in chronic lymphocytic leukemia., Ouillette, Peter, Li Jinghui, Shaknovich Rita, Li Yifeng, Melnick Ari, Shedden Kerby, and Malek Sami N. , Genes Chromosomes Cancer, 2012 Dec, Volume 51, Issue 12, p.1125-32, (2012)
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia., Geng, Huimin, Brennan Sarah, Milne Thomas A., Chen Wei-Yi, Li Yushan, Hurtz Christian, Kweon Soo-Mi, Zickl Lynette, Shojaee Seyedmehdi, Neuberg Donna, et al. , Cancer Discov, 2012 Nov, Volume 2, Issue 11, p.1004-23, (2012)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles., Akalin, Altuna, Kormaksson Matthias, Li Sheng, Garrett-Bakelman Francine E., Figueroa Maria E., Melnick Ari, and Mason Christopher E. , Genome Biol, 2012 Oct 03, Volume 13, Issue 10, p.R87, (2012)
A molecular roadmap of reprogramming somatic cells into iPS cells., Polo, Jose M., Anderssen Endre, Walsh Ryan M., Schwarz Benjamin A., Nefzger Christian M., Lim Sue Mei, Borkent Marti, Apostolou Effie, Alaei Sara, Cloutier Jennifer, et al. , Cell, 2012 Dec 21, Volume 151, Issue 7, p.1617-32, (2012)
Mutant DNMT3A: a marker of poor prognosis in acute myeloid leukemia., Ribeiro, Ana Flávia Ti, Pratcorona Marta, Erpelinck-Verschueren Claudia, Rockova Veronika, Sanders Mathijs, Abbas Saman, Figueroa Maria E., Zeilemaker Annelieke, Melnick Ari, Löwenberg Bob, et al. , Blood, 2012 Jun 14, Volume 119, Issue 24, p.5824-31, (2012)
Oncogene-mediated alterations in chromatin conformation., Rickman, David S., T Soong David, Moss Benjamin, Mosquera Juan Miguel, Dlabal Jan, Terry Stéphane, MacDonald Theresa Y., Tripodi Joseph, Bunting Karen, Najfeld Vesna, et al. , Proc Natl Acad Sci U S A, 2012 Jun 05, Volume 109, Issue 23, p.9083-8, (2012)
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia., Patel, Jay P., Gönen Mithat, Figueroa Maria E., Fernandez Hugo, Sun Zhuoxin, Racevskis Janis, Van Vlierberghe Pieter, Dolgalev Igor, Thomas Sabrena, Aminova Olga, et al. , N Engl J Med, 2012 Mar 22, Volume 366, Issue 12, p.1079-89, (2012)
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis., Busque, Lambert, Patel Jay P., Figueroa Maria E., Vasanthakumar Aparna, Provost Sylvie, Hamilou Zineb, Mollica Luigina, Li Juan, Viale Agnes, Heguy Adriana, et al. , Nat Genet, 2012 Nov, Volume 44, Issue 11, p.1179-81, (2012)
Targeting lymphomas through MALT1 inhibition., Fontan, Lorena, and Melnick Ari , Oncotarget, 2012 Dec, Volume 3, Issue 12, p.1493-4, (2012)
2011
Aberrant epigenetic and genetic marks are seen in myelodysplastic leukocytes and reveal Dock4 as a candidate pathogenic gene on chromosome 7q., Zhou, Li, Opalinska Joanna, Sohal Davendra, Yu Yiting, Mo Yongkai, Bhagat Tushar, Abdel-Wahab Omar, Fazzari Melissa, Figueroa Maria, Alencar Cristina, et al. , J Biol Chem, 2011 Jul 15, Volume 286, Issue 28, p.25211-23, (2011)
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90., Moulick, Kamalika, Ahn James H., Zong Hongliang, Rodina Anna, Cerchietti Leandro, DaGama Erica M. Gomes, Caldas-Lopes Eloisi, Beebe Kristin, Perna Fabiana, Hatzi Katerina, et al. , Nat Chem Biol, 2011 Sep 25, Volume 7, Issue 11, p.818-26, (2011)
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition., Duy, Cihangir, Hurtz Christian, Shojaee Seyedmehdi, Cerchietti Leandro, Geng Huimin, Swaminathan Srividya, Klemm Lars, Kweon Soo-Mi, Nahar Rahul, Braig Melanie, et al. , Nature, 2011 May 19, Volume 473, Issue 7347, p.384-8, (2011)
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia., Hurtz, Christian, Hatzi Katerina, Cerchietti Leandro, Braig Melanie, Park Eugene, Kim Yong-mi, Herzog Sebastian, Ramezani-Rad Parham, Jumaa Hassan, Müller Martin C., et al. , J Exp Med, 2011 Oct 24, Volume 208, Issue 11, p.2163-74, (2011)
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation., Shaknovich, Rita, Cerchietti Leandro, Tsikitas Lucas, Kormaksson Matthias, De Subhajyoti, Figueroa Maria E., Ballon Gianna, Yang Shao Ning, Weinhold Nils, Reimers Mark, et al. , Blood, 2011 Sep 29, Volume 118, Issue 13, p.3559-69, (2011)
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma., Oricchio, Elisa, Nanjangud Gouri, Wolfe Andrew L., Schatz Jonathan H., Mavrakis Konstantinos J., Jiang Man, Liu Xiaoping, Bruno Joanne, Heguy Adriana, Olshen Adam B., et al. , Cell, 2011 Oct 28, Volume 147, Issue 3, p.554-64, (2011)
Epigenetics and B-cell lymphoma., Shaknovich, Rita, and Melnick Ari , Curr Opin Hematol, 2011 Jul, Volume 18, Issue 4, p.293-9, (2011)
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas., Cerchietti, Leandro, Damm-Welk Christine, Vater Inga, Klapper Wolfram, Harder Lana, Pott Christiane, Yang Shao Ning, Reiter Alfred, Siebert Reiner, Melnick Ari, et al. , PLoS One, 2011 Apr 08, Volume 6, Issue 4, p.e18436, (2011)
The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation., Wang, Lan, Gural Alexander, Sun Xiao-Jian, Zhao Xinyang, Perna Fabiana, Huang Gang, Hatlen Megan A., Vu Ly, Liu Fan, Xu Haiming, et al. , Science, 2011 Aug 05, Volume 333, Issue 6043, p.765-9, (2011)
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC., Nahar, Rahul, Ramezani-Rad Parham, Mossner Maximilian, Duy Cihangir, Cerchietti Leandro, Geng Huimin, Dovat Sinisa, Jumaa Hassan, B Ye Hilda, Melnick Ari, et al. , Blood, 2011 Oct 13, Volume 118, Issue 15, p.4174-8, (2011)
SYK inhibition and response prediction in diffuse large B-cell lymphoma., Cheng, Shuhua, Coffey Greg, X Zhang Hannah, Shaknovich Rita, Song Zibo, Lu Pin, Pandey Anjali, Melnick Ari M., Sinha Uma, and Y Wang Lynn , Blood, 2011 Dec 08, Volume 118, Issue 24, p.6342-52, (2011)
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation., Moran-Crusio, Kelly, Reavie Linsey, Shih Alan, Abdel-Wahab Omar, Ndiaye-Lobry Delphine, Lobry Camille, Figueroa Maria E., Vasanthakumar Aparna, Patel Jay, Zhao Xinyang, et al. , Cancer Cell, 2011 Jul 12, Volume 20, Issue 1, p.11-24, (2011)