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Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma.,
Saba, Nakhle S., Liu Delong, Herman Sarah E. M., Underbayev Chingiz, Tian Xin, Behrend David, Weniger Marc A., Skarzynski Martin, Gyamfi Jennifer, Fontan Lorena, et al.
, Blood, 2016 Jul 07, Volume 128, Issue 1, p.82-92, (2016)
PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.,
Pascual, Marien, Mena-Varas Maria, Robles Eloy Francisco, Garcia-Barchino Maria-Jose, Panizo Carlos, Hervas-Stubbs Sandra, Alignani Diego, Sagardoy Ainara, Martinez-Ferrandis Jose Ignacio, Bunting Karen L., et al.
, Blood, 2019 May 30, Volume 133, Issue 22, p.2401-2412, (2019)
Peptide-based covalent inhibitors of MALT1 paracaspase.,
Hatcher, John M., Du Guangyan, Fontan Lorena, Us Ilkay, Qiao Qi, Chennamadhavuni Spandan, Shao Jay, Wu Hao, Melnick Ari, Gray Nathanael S., et al.
, Bioorg Med Chem Lett, 2019 Jun 01, Volume 29, Issue 11, p.1336-1339, (2019)
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.,
Cerchietti, Leandro C., Yang Shao Ning, Shaknovich Rita, Hatzi Katerina, Polo Jose M., Chadburn Amy, Dowdy Steven F., and Melnick Ari
, Blood, 2009 Apr 09, Volume 113, Issue 15, p.3397-405, (2009)
Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma.,
Goldstein, Rebecca L., Yang Shao Ning, Taldone Tony, Chang Betty, Gerecitano John, Elenitoba-Johnson Kojo, Shaknovich Rita, Tam Wayne, Leonard John P., Chiosis Gabriela, et al.
, J Clin Invest, 2015 Nov 03, Volume 125, Issue 12, p.4559-71, (2015)
Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.,
Nahar, Rahul, Ramezani-Rad Parham, Mossner Maximilian, Duy Cihangir, Cerchietti Leandro, Geng Huimin, Dovat Sinisa, Jumaa Hassan, B Ye Hilda, Melnick Ari, et al.
, Blood, 2011 Oct 13, Volume 118, Issue 15, p.4174-8, (2011)
PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex.,
Vu, Ly P., Perna Fabiana, Wang Lan, Voza Francesca, Figueroa Maria E., Tempst Paul, Erdjument-Bromage Hediye, Gao Rui, Chen Sisi, Paietta Elisabeth, et al.
, Cell Rep, 2013 Dec 26, Volume 5, Issue 6, p.1625-38, (2013)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival.,
Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al.
, Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.,
Patel, Jay P., Gönen Mithat, Figueroa Maria E., Fernandez Hugo, Sun Zhuoxin, Racevskis Janis, Van Vlierberghe Pieter, Dolgalev Igor, Thomas Sabrena, Aminova Olga, et al.
, N Engl J Med, 2012 Mar 22, Volume 366, Issue 12, p.1079-89, (2012)
Prolonged administration of azacitidine with or without entinostat for myelodysplastic syndrome and acute myeloid leukemia with myelodysplasia-related changes: results of the US Leukemia Intergroup trial E1905.,
Prebet, Thomas, Sun Zhuoxin, Figueroa Maria E., Ketterling Rhett, Melnick Ari, Greenberg Peter L., Herman James, Juckett Mark, Smith Mitchell R., Malick Lisa, et al.
, J Clin Oncol, 2014 Apr 20, Volume 32, Issue 12, p.1242-8, (2014)
Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.,
Schafer, Eric, Irizarry Rafael, Negi Sandeep, McIntyre Emily, Small Donald, Figueroa Maria E., Melnick Ari, and Brown Patrick
, Blood, 2010 Jun 10, Volume 115, Issue 23, p.4798-809, (2010)
The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.,
Ball, H J., Melnick A, Shaknovich R, Kohanski R A., and Licht J D.
, Nucleic Acids Res, 1999 Oct 15, Volume 27, Issue 20, p.4106-13, (1999)
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells.,
Shojaee, Seyedmehdi, Chan Lai N., Buchner Maike, Cazzaniga Valeria, Cosgun Kadriye Nehir, Geng Huimin, Qiu Yi Hua, von Minden Marcus Dühren, Ernst Thomas, Hochhaus Andreas, et al.
, Nat Med, 2016 Apr, Volume 22, Issue 4, p.379-87, (2016)
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas.,
Cerchietti, Leandro C., Lopes Eloisi C., Yang Shao Ning, Hatzi Katerina, Bunting Karen L., Tsikitas Lucas A., Mallik Alka, Robles Ana I., Walling Jennifer, Varticovski Lyuba, et al.
, Nat Med, 2009 Dec, Volume 15, Issue 12, p.1369-76, (2009)
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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.,
Duy, Cihangir, Teater Matt, Garrett-Bakelman Francine E., Lee Tak C., Meydan Cem, Glass Jacob L., Li Meng, Hellmuth Johannes C., Mohammad Helai P., Smitheman Kimberly N., et al.
, Cancer Discov, 2019 Jul, Volume 9, Issue 7, p.872-889, (2019)
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma.,
Cardenas, Mariano G., Yu Wenbo, Béguelin Wendy, Teater Matthew R., Geng Huimin, Goldstein Rebecca L., Oswald Erin, Hatzi Katerina, Yang Shao-Ning, Cohen Joanna, et al.
, J Clin Invest, 2016 Sep 01, Volume 126, Issue 9, p.3351-62, (2016)
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.,
Busque, Lambert, Patel Jay P., Figueroa Maria E., Vasanthakumar Aparna, Provost Sylvie, Hamilou Zineb, Mollica Luigina, Li Juan, Viale Agnes, Heguy Adriana, et al.
, Nat Genet, 2012 Nov, Volume 44, Issue 11, p.1179-81, (2012)
Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.,
Licht, J D., Shaknovich R, English M A., Melnick A, Li J Y., Reddy J C., Dong S, Chen S J., Zelent A, and Waxman S
, Oncogene, 1996 Jan 18, Volume 12, Issue 2, p.323-36, (1996)
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status".,
LaFave, Lindsay M., Béguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al.
, Nat Med, 2016 Jun 07, Volume 22, Issue 6, p.578-9, (2016)
Response to second-line therapy defines the potential for cure in patients with recurrent diffuse large B-cell lymphoma: implications for the development of novel therapeutic strategies.,
Elstrom, Rebecca L., Martin Peter, Ostrow Katya, Barrientos Jacqueline, Chadburn Amy, Furman Richard, Ruan Jia, Shore Tsiporah, Schuster Michael, Cerchietti Leandro, et al.
, Clin Lymphoma Myeloma Leuk, 2010 Jun, Volume 10, Issue 3, p.192-6, (2010)
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells.,
Polo, Jose M., Ci Weimin, Licht Jonathan D., and Melnick Ari
, Blood, 2008 Aug 01, Volume 112, Issue 3, p.644-51, (2008)
A roadmap for discovery and translation in lymphoma.,
Weinstock, David M., Dalla-Favera Riccardo, Gascoyne Randy D., Leonard John P., Levy Ronald, Lossos Izidore S., Melnick Ari M., Nowakowski Grzegorz S., Press Oliver W., Savage Kerry J., et al.
, Blood, 2015 Mar 26, Volume 125, Issue 13, p.2175-7, (2015)
Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.,
Nandi, Sayan, Chandramohan Dhruva, Fioriti Luana, Melnick Ari M., Hébert Jean M., Mason Christopher E., Rajasethupathy Priyamvada, and Kandel Eric R.
, Proc Natl Acad Sci U S A, 2016 Nov 08, Volume 113, Issue 45, p.12697-12702, (2016)