Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain., Nandi, Sayan, Chandramohan Dhruva, Fioriti Luana, Melnick Ari M., Hébert Jean M., Mason Christopher E., Rajasethupathy Priyamvada, and Kandel Eric R. , Proc Natl Acad Sci U S A, 2016 Nov 08, Volume 113, Issue 45, p.12697-12702, (2016)

Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphoma., Dupont, Thibault, Yang Shao Ning, Patel Jayeshkumar, Hatzi Katerina, Malik Alka, Tam Wayne, Martin Peter, Leonard John, Melnick Ari, and Cerchietti Leandro , Oncotarget, 2016 Jan 19, Volume 7, Issue 3, p.3520-32, (2016)

SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents., Fiskus, Warren, Coothankandaswamy Veena, Chen Jianguang, Ma Hongwei, Ha Kyungsoo, Saenz Dyana T., Krieger Stephanie S., Mill Christopher P., Sun Baohua, Huang Peng, et al. , Cancer Res, 2016 Sep 15, Volume 76, Issue 18, p.5467-78, (2016)

BCL6 Antagonizes NOTCH2 to Maintain Survival of Human Follicular Lymphoma Cells., Valls, Ester, Lobry Camille, Geng Huimin, Wang Ling, Cardenas Mariano, Rivas Martín, Cerchietti Leandro, Oh Philmo, Yang Shao Ning, Oswald Erin, et al. , Cancer Discov, 2017 May, Volume 7, Issue 5, p.506-521, (2017)

CD99 is a therapeutic target on disease stem cells in myeloid malignancies., Chung, Stephen S., Eng William S., Hu Wenhuo, Khalaj Mona, Garrett-Bakelman Francine E., Tavakkoli Montreh, Levine Ross L., Carroll Martin, Klimek Virginia M., Melnick Ari M., et al. , Sci Transl Med, 2017 Jan 25, Volume 9, Issue 374, (2017)

Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury., Li, Yong, Huang Xuan, Huang Shengping, He Hui, Lei Tianhua, Saaoud Fatma, Yu Xiao-Qiang, Melnick Ari, Kumar Anil, Papasian Christopher J., et al. , Signal Transduct Target Ther, 2017, Volume 2, p.17066, (2017)

Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in - and -Mutant Acute Myeloid Leukemia., Shih, Alan H., Meydan Cem, Shank Kaitlyn, Garrett-Bakelman Francine E., Ward Patrick S., Intlekofer Andrew M., Nazir Abbas, Stein Eytan M., Knapp Kristina, Glass Jacob, et al. , Cancer Discov, 2017 May, Volume 7, Issue 5, p.494-505, (2017)

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas., Jiang, Yanwen, Ortega-Molina Ana, Geng Huimin, Ying Hsia-Yuan, Hatzi Katerina, Parsa Sara, McNally Dylan, Wang Ling, Doane Ashley S., Agirre Xabier, et al. , Cancer Discov, 2017 Jan, Volume 7, Issue 1, p.38-53, (2017)

DNA Methylation-Based Biomarkers., Cerchietti, Leandro, and Melnick Ari , J Clin Oncol, 2017 Mar, Volume 35, Issue 7, p.793-795, (2017)

Effective Combination Therapies for B-cell Lymphoma Predicted by a Virtual Disease Model., Du, Wei, Goldstein Rebecca, Jiang Yanwen, Aly Omar, Cerchietti Leandro, Melnick Ari, and Elemento Olivier , Cancer Res, 2017 Apr 15, Volume 77, Issue 8, p.1818-1830, (2017)

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers., Glass, Jacob L., Hassane Duane, Wouters Bas J., Kunimoto Hiroyoshi, Avellino Roberto, Garrett-Bakelman Francine E., Guryanova Olga A., Bowman Robert, Redlich Shira, Intlekofer Andrew M., et al. , Cancer Discov, 2017 Aug, Volume 7, Issue 8, p.868-883, (2017)

The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target., Cardenas, Mariano G., Oswald Erin, Yu Wenbo, Xue Fengtian, MacKerell Alexander D., and Melnick Ari M. , Clin Cancer Res, 2017 Feb 15, Volume 23, Issue 4, p.885-893, (2017)

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop., Béguelin, Wendy, Rivas Martín A., Fernández María T. Calvo, Teater Matt, Purwada Alberto, Redmond David, Shen Hao, Challman Matt F., Elemento Olivier, Singh Ankur, et al. , Nat Commun, 2017 Oct 12, Volume 8, Issue 1, p.877, (2017)

Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015., Gascoyne, Randy D., Nadel Bertrand, Pasqualucci Laura, Fitzgibbon Jude, Payton Jacqueline E., Melnick Ari, Weigert Oliver, Tarte Karin, Gribben John G., Friedberg Jonathan W., et al. , Hematol Oncol, 2017 Dec, Volume 35, Issue 4, p.397-407, (2017)

Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells., Vu, Ly P., Prieto Camila, Amin Elianna M., Chhangawala Sagar, Krivtsov Andrei, M Calvo-Vidal Nieves, Chou Timothy, Chow Arthur, Minuesa Gerard, Park Sun Mi, et al. , Nat Genet, 2017 Jun, Volume 49, Issue 6, p.866-875, (2017)

Genetic and epigenetic inactivation of controls mTORC1 and response to EZH2 inhibition in follicular lymphoma., Oricchio, Elisa, Katanayeva Natalya, Donaldson Maria Christine, Sungalee Stephanie, Pasion Joyce P., Béguelin Wendy, Battistello Elena, Sanghvi Viraj R., Jiang Man, Jiang Yanwen, et al. , Sci Transl Med, 2017 Jun 28, Volume 9, Issue 396, (2017)

is a key regulator of myeloid/erythroid differentiation and DNA methylation in hematopoietic stem/progenitor cells., Kunimoto, Hiroyoshi, McKenney Anna Sophia, Meydan Cem, Shank Kaitlyn, Nazir Abbas, Rapaport Franck, Durham Benjamin, Garrett-Bakelman Francine E., Pronier Elodie, Shih Alan H., et al. , Blood, 2017 Mar 30, Volume 129, Issue 13, p.1779-1790, (2017)

MALT1 Inhibition Is Efficacious in Both Naïve and Ibrutinib-Resistant Chronic Lymphocytic Leukemia., Saba, Nakhle S., Wong Deanna H., Tanios Georges, Iyer Jessica R., Lobelle-Rich Patricia, Dadashian Eman L., Liu Delong, Fontan Lorena, Flemington Erik K., Nichols Cydney M., et al. , Cancer Res, 2017 Dec 15, Volume 77, Issue 24, p.7038-7048, (2017)

The N-methyladenosine (mA)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells., Vu, Ly P., Pickering Brian F., Cheng Yuanming, Zaccara Sara, Nguyen Diu, Minuesa Gerard, Chou Timothy, Chow Arthur, Saletore Yogesh, MacKay Matthew, et al. , Nat Med, 2017 Nov, Volume 23, Issue 11, p.1369-1376, (2017)

Untangling the Web of Lymphoma Somatic Mutations., Teater, Matt, and Melnick Ari , Cell, 2017 Oct 05, Volume 171, Issue 2, p.270-272, (2017)

AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis., Teater, Matt, Dominguez Pilar M., Redmond David, Chen Zhengming, Ennishi Daisuke, Scott David W., Cimmino Luisa, Ghione Paola, Chaudhuri Jayanta, Gascoyne Randy D., et al. , Nat Commun, 2018 Jan 15, Volume 9, Issue 1, p.222, (2018)

Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity., Kunimoto, Hiroyoshi, Meydan Cem, Nazir Abbas, Whitfield Justin, Shank Kaitlyn, Rapaport Franck, Maher Rebecca, Pronier Elodie, Meyer Sara C., Garrett-Bakelman Francine E., et al. , Cancer Cell, 2018 Jan 08, Volume 33, Issue 1, p.44-59.e8, (2018)

Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs., Noh, Kyung-Min, Wang Haibo, Kim Hyunjae R., Wenderski Wendy, Fang Fang, Li Charles H., Dewell Scott, Hughes Stephen H., Melnick Ari M., Patel Dinshaw J., et al. , Mol Cell, 2018 Feb 01, Volume 69, Issue 3, p.533, (2018)

Enhancer of zeste homolog 2 (EZH2) inhibitors., Gulati, Nitya, Béguelin Wendy, and Giulino-Roth Lisa , Leuk Lymphoma, 2018 Jul, Volume 59, Issue 7, p.1574-1585, (2018)

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis., Pronier, Elodie, Bowman Robert L., Ahn Jihae, Glass Jacob, Kandoth Cyriac, Merlinsky Tiffany R., Whitfield Justin T., Durham Benjamin H., Gruet Antoine, Somasundara Amritha Varshini H., et al. , Blood, 2018 Sep 20, Volume 132, Issue 12, p.1265-1278, (2018)