Found 271 results
2009
Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells., Laurenzana, Anna, Petruccelli Luca A., Pettersson Filippa, Figueroa Maria Eugenia, Melnick Ari, Baldwin Albert S., Paoletti Francesco, and Miller Wilson H. , Cancer Res, 2009 Jan 01, Volume 69, Issue 1, p.55-64, (2009)
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation., Figueroa, Maria E., Skrabanek Lucy, Li Yushan, Jiemjit Anchalee, Fandy Tamer E., Paietta Elisabeth, Fernandez Hugo, Tallman Martin S., Greally John M., Carraway Hetty, et al. , Blood, 2009 Oct 15, Volume 114, Issue 16, p.3448-58, (2009)
Outcome of deferred initial therapy in mantle-cell lymphoma., Martin, Peter, Chadburn Amy, Christos Paul, Weil Karen, Furman Richard R., Ruan Jia, Elstrom Rebecca, Niesvizky Ruben, Ely Scott, Diliberto Maurizio, et al. , J Clin Oncol, 2009 Mar 10, Volume 27, Issue 8, p.1209-13, (2009)
A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo., Cerchietti, Leandro C., Yang Shao Ning, Shaknovich Rita, Hatzi Katerina, Polo Jose M., Chadburn Amy, Dowdy Steven F., and Melnick Ari , Blood, 2009 Apr 09, Volume 113, Issue 15, p.3397-405, (2009)
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas., Cerchietti, Leandro C., Lopes Eloisi C., Yang Shao Ning, Hatzi Katerina, Bunting Karen L., Tsikitas Lucas A., Mallik Alka, Robles Ana I., Walling Jennifer, Varticovski Lyuba, et al. , Nat Med, 2009 Dec, Volume 15, Issue 12, p.1369-76, (2009)
2008
B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma., Ci, Weimin, Polo Jose M., and Melnick Ari , Curr Opin Hematol, 2008 Jul, Volume 15, Issue 4, p.381-90, (2008)
BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells., Ranuncolo, Stella M., Polo Jose M., and Melnick Ari , Blood Cells Mol Dis, 2008 Jul-Aug, Volume 41, Issue 1, p.95-9, (2008)
BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner., Ranuncolo, Stella Maris, Wang Ling, Polo Jose M., Dell'Oso Tania, Dierov Jamil, Gaymes Terry J., Rassool Feyruz, Carroll Martin, and Melnick Ari , J Biol Chem, 2008 Aug 15, Volume 283, Issue 33, p.22565-72, (2008)
CtBP is an essential corepressor for BCL6 autoregulation., Mendez, Lourdes M., Polo Jose M., J Yu Jessica, Krupski Melissa, B Ding Belinda, Melnick Ari, and B Ye Hilda , Mol Cell Biol, 2008 Apr, Volume 28, Issue 7, p.2175-86, (2008)
Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics., Zelent, Arthur, Petrie Kevin, Boix-Chornet Manuel, Melnick Ari M., Waxman Samuel, and Gore Steven D. , Cancer Res, 2008 Jul 01, Volume 68, Issue 13, p.4967-70, (2008)
HDAC4 promotes growth of colon cancer cells via repression of p21., Wilson, Andrew J., Byun Do-Sun, Nasser Shannon, Murray Lucas B., Ayyanar Kanyalakshmi, Arango Diego, Figueroa Maria, Melnick Ari, Kao Gary D., Augenlicht Leonard H., et al. , Mol Biol Cell, 2008 Oct, Volume 19, Issue 10, p.4062-75, (2008)
An integrative genomic and epigenomic approach for the study of transcriptional regulation., Figueroa, Maria E., Reimers Mark, Thompson Reid F., Ye Kenny, Li Yushan, Selzer Rebecca R., Fridriksson Jakob, Paietta Elisabeth, Wiernik Peter, Green Roland D., et al. , PLoS One, 2008 Mar 26, Volume 3, Issue 3, p.e1882, (2008)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
Meta-analysis of microarray studies reveals a novel hematopoietic progenitor cell signature and demonstrates feasibility of inter-platform data integration., Sohal, Davendra, Yeatts Andrew, Ye Kenny, Pellagatti Andrea, Zhou Li, Pahanish Perry, Mo Yongkai, Bhagat Tushar, Mariadason John, Boultwood Jacqueline, et al. , PLoS One, 2008 Aug 13, Volume 3, Issue 8, p.e2965, (2008)
Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells., Polo, Jose M., Ci Weimin, Licht Jonathan D., and Melnick Ari , Blood, 2008 Aug 01, Volume 112, Issue 3, p.644-51, (2008)
Sequential transcription factor targeting for diffuse large B-cell lymphomas., Cerchietti, Leandro C., Polo Jose M., Da Silva Gustavo F., Farinha Pedro, Shaknovich Rita, Gascoyne Randy D., Dowdy Steven F., and Melnick Ari , Cancer Res, 2008 May 01, Volume 68, Issue 9, p.3361-9, (2008)
Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer., Ghetu, Alexandru F., Corcoran Connie M., Cerchietti Leandro, Bardwell Vivian J., Melnick Ari, and Prive Gilbert G. , Mol Cell, 2008 Feb 15, Volume 29, Issue 3, p.384-91, (2008)
Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas., Parekh, Samir, Privé Gilbert, and Melnick Ari , Leuk Lymphoma, 2008 May, Volume 49, Issue 5, p.874-82, (2008)
Transitioning from fellowship to a physician-scientist career track., Melnick, Ari , Hematology Am Soc Hematol Educ Program, 2008, p.16-22, (2008)