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Molecular pathways: targeting MALT1 paracaspase activity in lymphoma., Fontan, Lorena, and Melnick Ari , Clin Cancer Res, 2013 Dec 15, Volume 19, Issue 24, p.6662-8, (2013)
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth., Fontan, Lorena, Qiao Qi, Hatcher John M., Casalena Gabriella, Us Ilkay, Teater Matt, Durant Matt, Du Guangyan, Xia Min, Bilchuk Natalia, et al. , J Clin Invest, 2018 Oct 01, Volume 128, Issue 10, p.4397-4412, (2018)
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo., Fontan, Lorena, Yang Chenghua, Kabaleeswaran Venkataraman, Volpon Laurent, Osborne Michael J., Beltran Elena, Garcia Monica, Cerchietti Leandro, Shaknovich Rita, Yang Shao Ning, et al. , Cancer Cell, 2012 Dec 11, Volume 22, Issue 6, p.812-24, (2012)
Targeting lymphomas through MALT1 inhibition., Fontan, Lorena, and Melnick Ari , Oncotarget, 2012 Dec, Volume 3, Issue 12, p.1493-4, (2012)
Discovering what makes STAT signaling TYK in T-ALL., Fontan, Lorena, and Melnick Ari , Cancer Discov, 2013 May, Volume 3, Issue 5, p.494-6, (2013)
An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities., Flümann, Ruth, Rehkämper Tim, Nieper Pascal, Pfeiffer Pauline, Holzem Alessandra, Klein Sebastian, Bhatia Sanil, Kochanek Moritz, Kisis Ilmars, Pelzer Benedikt W., et al. , Blood Cancer Discov, 2021 Jan, Volume 2, Issue 1, p.70-91, (2021)
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia., Fiskus, Warren, Saba Nakhle, Shen Min, Ghias Mondana, Liu Jinyun, Gupta Soumyasri Das, Chauhan Lata, Rao Rekha, Gunewardena Sumedha, Schorno Kevin, et al. , Cancer Res, 2014 May 01, Volume 74, Issue 9, p.2520-32, (2014)
SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents., Fiskus, Warren, Coothankandaswamy Veena, Chen Jianguang, Ma Hongwei, Ha Kyungsoo, Saenz Dyana T., Krieger Stephanie S., Mill Christopher P., Sun Baohua, Huang Peng, et al. , Cancer Res, 2016 09 15, Volume 76, Issue 18, p.5467-78, (2016)
An integrative genomic and epigenomic approach for the study of transcriptional regulation., Figueroa, Maria E., Reimers Mark, Thompson Reid F., Ye Kenny, Li Yushan, Selzer Rebecca R., Fridriksson Jakob, Paietta Elisabeth, Wiernik Peter, Green Roland D., et al. , PLoS One, 2008 Mar 26, Volume 3, Issue 3, p.e1882, (2008)
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation., Figueroa, Maria E., Abdel-Wahab Omar, Lu Chao, Ward Patrick S., Patel Jay, Shih Alan, Li Yushan, Bhagwat Neha, Vasanthakumar Aparna, Fernandez Hugo F., et al. , Cancer Cell, 2010 Dec 14, Volume 18, Issue 6, p.553-67, (2010)
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features., Figueroa, Maria E., Wouters Bas J., Skrabanek Lucy, Glass Jacob, Li Yushan, Erpelinck-Verschueren Claudia A. J., Langerak Anton W., Löwenberg Bob, Fazzari Melissa, Greally John M., et al. , Blood, 2009 Mar 19, Volume 113, Issue 12, p.2795-804, (2009)
MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation., Figueroa, Maria E., Skrabanek Lucy, Li Yushan, Jiemjit Anchalee, Fandy Tamer E., Paietta Elisabeth, Fernandez Hugo, Tallman Martin S., Greally John M., Carraway Hetty, et al. , Blood, 2009 Oct 15, Volume 114, Issue 16, p.3448-58, (2009)
Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias., Figueroa, Maria E., Melnick Ari, and Greally John M. , Methods Mol Biol, 2009, Volume 538, p.395-407, (2009)
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia., Figueroa, Maria E., Lugthart Sanne, Li Yushan, Erpelinck-Verschueren Claudia, Deng Xutao, Christos Paul J., Schifano Elizabeth, Booth James, van Putten Wim, Skrabanek Lucy, et al. , Cancer Cell, 2010 Jan 19, Volume 17, Issue 1, p.13-27, (2010)
Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia., Figueroa, Maria E., Chen Shann-Ching, Andersson Anna K., Phillips Letha A., Li Yushan, Sotzen Jason, Kundu Mondira, Downing James R., Melnick Ari, and Mullighan Charles G. , J Clin Invest, 2013 Jul, Volume 123, Issue 7, p.3099-111, (2013)
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress., Fernando, Tharu M., Marullo Rossella, Gresely Benet Pera, Phillip Jude M., Yang Shao Ning, Lundell-Smith Geoffrey, Torregroza Ingrid, Ahn Haelee, Evans Todd, Gyorffy Balazs, et al. , Cancer Discov, 2019 May, Volume 9, Issue 5, p.662-679, (2019)
The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy., Fabre, Marie-Sophie, Stanton Nicole M., Slatter Tania L., Lee Samuel, Senanayake Dinindu, Gordon Rosemary M. A., M Castro Leticia, Rowe Matthew R., Taha Ahmad, Royds Janice A., et al. , PLoS One, 2020, Volume 15, Issue 4, p.e0231470, (2020)