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A clinical measure of DNA methylation predicts outcome in de novo acute myeloid leukemia., Luskin, Marlise R., Gimotty Phyllis A., Smith Catherine, Loren Alison W., Figueroa Maria E., Harrison Jenna, Sun Zhuoxin, Tallman Martin S., Paietta Elisabeth M., Litzow Mark R., et al. , JCI Insight, 2016 Jun 16, Volume 1, Issue 9, (2016)
Induction of sarcomas by mutant IDH2., Lu, Chao, Venneti Sriram, Akalin Altuna, Fang Fang, Ward Patrick S., Dematteo Raymond G., Intlekofer Andrew M., Chen Chong, Ye Jiangbin, Hameed Meera, et al. , Genes Dev, 2013 Sep 15, Volume 27, Issue 18, p.1986-98, (2013)
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival., Lu, Xiaoqing, Fernando Tharu M., Lossos Chen, Yusufova Nevin, Liu Fan, Fontan Lorena, Durant Matthew, Geng Huimin, Melnick Jacob, Luo Yuan, et al. , Blood, 2018 Nov 08, Volume 132, Issue 19, p.2026-2039, (2018)
BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements., Lu, Zhengfei, Tsai Albert G., Akasaka Takashi, Ohno Hitoshi, Jiang Yanwen, Melnick Ari M., Greisman Harvey A., and Lieber Michael R. , Blood, 2013 May 30, Volume 121, Issue 22, p.4551-4, (2013)
MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition., Lu, Xiangdong, Chu Chi-Shuen, Fang Terry, Rayon-Estrada Violeta, Fang Fang, Patke Alina, Qian Ye, Clarke Stephen H., Melnick Ari M., Zhang Yi, et al. , Cell Rep, 2019 Jul 09, Volume 28, Issue 2, p.472-485.e5, (2019)
IDH mutation impairs histone demethylation and results in a block to cell differentiation., Lu, Chao, Ward Patrick S., Kapoor Gurpreet S., Rohle Dan, Turcan Sevin, Abdel-Wahab Omar, Edwards Christopher R., Khanin Raya, Figueroa Maria E., Melnick Ari, et al. , Nature, 2012 Feb 15, Volume 483, Issue 7390, p.474-8, (2012)
Kaiso contributes to DNA methylation-dependent silencing of tumor suppressor genes in colon cancer cell lines., Lopes, Eloisi C., Valls Ester, Figueroa Maria E., Mazur Alexander, Meng Fan-Guo, Chiosis Gabriela, Laird Peter W., Schreiber-Agus Nicole, Greally John M., Prokhortchouk Egor, et al. , Cancer Res, 2008 Sep 15, Volume 68, Issue 18, p.7258-63, (2008)
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression., Lin, Pei-Chun, Chiu Ya-Lin, Banerjee Samprit, Park Kyung, Mosquera Juan Miguel, Giannopoulou Eugenia, Alves Pedro, Tewari Ashutosh K., Gerstein Mark B., Beltran Himisha, et al. , Cancer Res, 2013 Feb 01, Volume 73, Issue 3, p.1232-44, (2013)
Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia., Licht, J D., Shaknovich R, English M A., Melnick A, Li J Y., Reddy J C., Dong S, Chen S J., Zelent A, and Waxman S , Oncogene, 1996 Jan 18, Volume 12, Issue 2, p.323-36, (1996)
An "EZ" Epigenetic Road to Leukemia Stem Cell Metabolic Reprogramming?, Li, Meng, and Melnick Ari M. , Cancer Discov, 2019 Sep, Volume 9, Issue 9, p.1158-1160, (2019)
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia., Li, Sheng, Garrett-Bakelman Francine E., Chung Stephen S., Sanders Mathijs A., Hricik Todd, Rapaport Franck, Patel Jay, Dillon Richard, Vijay Priyanka, Brown Anna L., et al. , Nat Med, 2016 07, Volume 22, Issue 7, p.792-9, (2016)
Dynamic evolution of clonal epialleles revealed by methclone., Li, Sheng, Garrett-Bakelman Francine, Perl Alexander E., Luger Selina M., Zhang Chao, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., M Ross Elizabeth, et al. , Genome Biol, 2014 Sep 27, Volume 15, Issue 9, p.472, (2014)
Somatic Mutations Drive Specific, but Reversible, Epigenetic Heterogeneity States in AML., Li, Sheng, Chen Xiaowen, Wang Jiahui, Meydan Cem, Glass Jacob L., Shih Alan H., Delwel Ruud, Levine Ross L., Mason Christopher E., and Melnick Ari M. , Cancer Discov, 2020 Dec, Volume 10, Issue 12, p.1934-1949, (2020)
Central role of myeloid MCPIP1 in protecting against LPS-induced inflammation and lung injury., Li, Yong, Huang Xuan, Huang Shengping, He Hui, Lei Tianhua, Saaoud Fatma, Yu Xiao-Qiang, Melnick Ari, Kumar Anil, Papasian Christopher J., et al. , Signal Transduct Target Ther, 2017, Volume 2, p.17066, (2017)
An optimized algorithm for detecting and annotating regional differential methylation., Li, Sheng, Garrett-Bakelman Francine E., Akalin Altuna, Zumbo Paul, Levine Ross, To Bik L., Lewis Ian D., Brown Anna L., D'Andrea Richard J., Melnick Ari, et al. , BMC Bioinformatics, 2013, Volume 14 Suppl 5, Issue Suppl 5, p.S10, (2013)
Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis., Li, Meng, Chiang Ying-Ling, Lyssiotis Costas A., Teater Matthew R., Hong Jun Young, Shen Hao, Wang Ling, Hu Jing, Jing Hui, Chen Zhengming, et al. , Cancer Cell, 2019 Jun 10, Volume 35, Issue 6, p.916-931.e9, (2019)
Genetic and epigenetic heterogeneity in acute myeloid leukemia., Li, Sheng, Mason Christopher E., and Melnick Ari , Curr Opin Genet Dev, 2016 02, Volume 36, p.100-6, (2016)
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma., Leshchenko, Violetta V., Kuo Pei-Yu, Shaknovich Rita, Yang David T., Gellen Tobias, Petrich Adam, Yu Yiting, Remache Yvonne, Weniger Marc A., Rafiq Sarwish, et al. , Blood, 2010 Aug 19, Volume 116, Issue 7, p.1025-34, (2010)
Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells., Laurenzana, Anna, Petruccelli Luca A., Pettersson Filippa, Figueroa Maria Eugenia, Melnick Ari, Baldwin Albert S., Paoletti Francesco, and Miller Wilson H. , Cancer Res, 2009 Jan 01, Volume 69, Issue 1, p.55-64, (2009)
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation., Lai, Anne Y., Mav Deepak, Shah Ruchir, Grimm Sara A., Phadke Dhiral, Hatzi Katerina, Melnick Ari, Geigerman Cissy, Sobol Steve E., Jaye David L., et al. , Genome Res, 2013 Dec, Volume 23, Issue 12, p.2030-41, (2013)
Loss of BAP1 function leads to EZH2-dependent transformation., LaFave, Lindsay M., B├ęguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2015 Nov, Volume 21, Issue 11, p.1344-9, (2015)
Reply to "Uveal melanoma cells are resistant to EZH2 inhibition regardless of BAP1 status"., LaFave, Lindsay M., B├ęguelin Wendy, Koche Richard, Teater Matt, Spitzer Barbara, Chramiec Alan, Papalexi Efthymia, Keller Matthew D., Hricik Todd, Konstantinoff Katerina, et al. , Nat Med, 2016 06 07, Volume 22, Issue 6, p.578-9, (2016)